Causal Impact of the Hospital Readmissions Reduction Program on Hospital Readmissions and Mortality

Estimating causal effects of the Hospital Readmissions Reduction Program (HRRP), part of the Affordable Care Act, has been very controversial. Associational studies have demonstrated decreases in hospital readmissions, consistent with the intent of the program, although analyses with different data sources and methods have differed in estimating effects on patient mortality. To address these issues, we define the estimands of interest in the context of potential outcomes, we formalize a Bayesian structural time-series model for causal inference, and discuss the necessary assumptions for estimation of effects using observed data. The method is used to estimate the effect of the passage of HRRP on both the 30-day readmissions and 30-day mortality. We show that for acute myocardial infarction and congestive heart failure, HRRP caused reduction in readmissions while it had no statistically significant effect on mortality. However, for pneumonia, HRRP had no statistically significant effect on readmissions but caused an increase in mortality.Comment: 10 pages, 1 figure, 2 table

Polynomial solutions of nonlinear integral equations

We analyze the polynomial solutions of a nonlinear integral equation, generalizing the work of C. Bender and E. Ben-Naim. We show that, in some cases, an orthogonal solution exists and we give its general form in terms of kernel polynomials.Comment: 10 page

Bayesian Model Averaging for Clustered Data: Imputing Missing Daily Air Pollution Concentration

The presence of missing observations is a challenge in statistical analysis especially when data are clustered. In this paper, we develop a Bayesian model averaging (BMA) approach for imputing missing observations in clustered data. Our approach extends BMA by allowing the weights of competing regression models for missing data imputation to vary between clusters while borrowing information across clusters in estimating model parameters. Through simulation and cross-validation studies, we demonstrate that our approach outperforms the standard BMA imputation approach where model weights are assumed to be the same for all clusters. We then apply our proposed method to a national dataset of daily ambient coarse particulate matter (PM10-2.5) concentration between 2003 and 2005. We impute missing daily monitor-level PM10-2.5 measurements and estimate the posterior probability of PM10-2.5 nonattainment status for 95 US counties based on the Environmental Protection Agency\u27s proposed 24-hour standard

Speech-Evoked Brainstem Response

The auditory brainstem response (ABR) is a clinical tool to assess the neural functionality of the auditory brainstem. The use of verbal stimuli in ABR protocols has provided important information of how the speech stimuli are processed by the brainstem structure. The perception of speech sounds seems to begin in the brainstem, which has an important role in the reading process and the phonological acquisition speech ABR assessment allows the identification of fine-grained auditory processing deficits, which do not appear in click evoked ABR responses. The syllable /da/ is commonly used by speech ABR assessment due to it being considered a universal syllable and allows it to be applied in different countries with good clinical assertiveness. The speech ABR is a objective, fast procedure that can be applied to very young subjects. It be utilized in different languages and can provide differential diagnoses of diseases with similar symptoms, as an effective biomarker of auditory processing disorders present in various diseases, such as dyslexia, specific language impairment, hearing loss, auditory processing disorders, otitis media, and scholastic difficulties. Speech ABR protocols can assist in the detection, treatment, and monitoring of various types of hearing impairments

Moose models with vanishing SS parameter

In the linear moose framework, which naturally emerges in deconstruction models, we show that there is a unique solution for the vanishing of the $S$ parameter at the lowest order in the weak interactions. We consider an effective gauge theory based on $K$ SU(2) gauge groups, $K+1$ chiral fields and electroweak groups $SU(2)_L$ and $U(1)_Y$ at the ends of the chain of the moose. $S$ vanishes when a link in the moose chain is cut. As a consequence one has to introduce a dynamical non local field connecting the two ends of the moose. Then the model acquires an additional custodial symmetry which protects this result. We examine also the possibility of a strong suppression of $S$ through an exponential behavior of the link couplings as suggested by Randall Sundrum metric.Comment: LaTex file, 27 pages, 8 figure

Consequences of a covariant Description of Heavy Ion Reactions at intermediate Energies

Heavy ion collisions at intermediate energies are studied by using a new RQMD code, which is a covariant generalization of the QMD approach. We show that this new implementation is able to produce the same results in the nonrelativistic limit (i.e. 50MeV/nucl.) as the non-covariant QMD. Such a comparison is not available in the literature. At higher energies (i.e. 1.5 GeV/nucl. and 2 GeV/nucl.) RQMD and QMD give different results in respect to the time evolution of the phase space, for example for the directed transverse flow. These differences show that consequences of a covariant description of heavy ion reactions within the framework of RQMD are existing even at intermediate energies.Comment: LaTex-file, 28 pages, 8 figures (available upon request), accepted for publication in Physical Review

Vortex and half-vortex dynamics in a spinor quantum fluid of interacting polaritons

Spinorial or multi-component Bose-Einstein condensates may sustain fractional quanta of circulation, vorticant topological excitations with half integer windings of phase and polarization. Matter-light quantum fluids, such as microcavity polaritons, represent a unique test bed for realising strongly interacting and out-of-equilibrium condensates. The direct access to the phase of their wavefunction enables us to pursue the quest of whether half vortices ---rather than full integer vortices--- are the fundamental topological excitations of a spinor polariton fluid. Here, we are able to directly generate by resonant pulsed excitations, a polariton fluid carrying either the half or full vortex states as initial condition, and to follow their coherent evolution using ultrafast holography. Surprisingly we observe a rich phenomenology that shows a stable evolution of a phase singularity in a single component as well as in the full vortex state, spiraling, splitting and branching of the initial cores under different regimes and the proliferation of many vortex anti-vortex pairs in self generated circular ripples. This allows us to devise the interplay of nonlinearity and sample disorder in shaping the fluid and driving the phase singularities dynamicsComment: New version complete with revised modelization, discussion and added material. 8 pages, 7 figures. Supplementary videos: https://drive.google.com/folderview?id=0B0QCllnLqdyBfmc2ai0yVF9fa2g2VnZodGUwemVkLThBb3BoOVRKRDJMS2dUdjlZdkRTQk

Top-BESS model and its phenomenology

We introduce the top-BESS model which is the effective description of the strong electroweak symmetry breaking with a single new SU(2)_L+R triplet vector resonance. The model is a modification of the BESS model in the fermion sector. The triplet couples to the third generation of quarks only. This approach reflects a possible extraordinary role of the top quark in the mechanism of electroweak symmetry breaking. The low-energy limits on the model parameters found provide hope for finding sizable signals in the LHC Drell-Yan processes as well as in the s-channel production processes at the ILC. However, there are regions of the model parameter space where the interplay of the direct and indirect fermion couplings can hide the resonance peak in a scattering process even though the resonance exists and couples directly to top and bottom quarks.Comment: published in Physical Review D, minor changes in text, 21 pages, 37 figure