2,379 research outputs found
Suspension and Measurement of Graphene and Bi2Se3 Atomic Membranes
Coupling high quality, suspended atomic membranes to specialized electrodes
enables investigation of many novel phenomena, such as spin or Cooper pair
transport in these two dimensional systems. However, many electrode materials
are not stable in acids that are used to dissolve underlying substrates. Here
we present a versatile and powerful multi-level lithographical technique to
suspend atomic membranes, which can be applied to the vast majority of
substrate, membrane and electrode materials. Using this technique, we
fabricated suspended graphene devices with Al electrodes and mobility of 5500
cm^2/Vs. We also demonstrate, for the first time, fabrication and measurement
of a free-standing thin Bi2Se3 membrane, which has low contact resistance to
electrodes and a mobility of >~500 cm^2/Vs
Dirac Equation at Finite Temperature
In this paper, we propose finite temperature Dirac equation, which can
describe the quantum systems in an arbitrary temperature for a relativistic
particle of spin-1/2. When the temperature T=0, it become Dirac equation. With
the equation, we can study the relativistic quantum systems in an arbitrary
temperature.Comment: arXiv admin note: text overlap with arXiv:1005.2751,
arXiv:hep-ph/0004125, arXiv:hep-ph/0005272 by other author
A mutation in Arabidopsis SAL1 alters its in vitro activity against IP3 and delays developmental leaf senescence in association with lower ROS levels
Key message: Our manuscript is the first to find a link between activity of SAL1/OLD101 against IP 3 and plant leaf senescence regulation and ROS levels assigning a potential biological role for IP 3. Abstract: Leaf senescence is a genetically programmed process that limits the longevity of a leaf. We identified and analyzed the recessive Arabidopsis stay-green mutation onset of leaf death 101 (old101). Developmental leaf longevity is extended in old101 plants, which coincided with higher peroxidase activity and decreased H 2O 2 levels in young 10-day-old, but not 25-day-old plants. The old101 phenotype is caused by a point mutation in SAL1, which encodes a bifunctional enzyme with inositol polyphosphate-1-phosphatase and 3′ (2′), 5′-bisphosphate nucleotidase activity. SAL1 activity is highly specific for its substrates 3-polyadenosine 5-phosphate (PAP) and inositol 1, 4, 5-trisphosphate (IP 3), where it removes the 1-phosphate group from the IP 3 second messenger. The in vitro activity of recombinant old101 protein against its substrate IP 3 was 2.5-fold lower than that of wild type SAL1 protein. However, the in vitro activity of recombinant old101 mutant protein against PAP remained the same as that of the wild type SAL1 protein. The results open the possibility that the activity of SAL1 against IP 3 may affect the redox balance of young seedlings and that this delays the onset of leaf senescence
OrgMining 2.0: A Novel Framework for Organizational Model Mining from Event Logs
Providing appropriate structures around human resources can streamline
operations and thus facilitate the competitiveness of an organization. To
achieve this goal, modern organizations need to acquire an accurate and timely
understanding of human resource grouping while faced with an ever-changing
environment. The use of process mining offers a promising way to help address
the need through utilizing event log data stored in information systems. By
extracting knowledge about the actual behavior of resources participating in
business processes from event logs, organizational models can be constructed,
which facilitate the analysis of the de facto grouping of human resources
relevant to process execution. Nevertheless, open research gaps remain to be
addressed when applying the state-of-the-art process mining to analyze resource
grouping. For one, the discovery of organizational models has only limited
connections with the context of process execution. For another, a rigorous
solution that evaluates organizational models against event log data is yet to
be proposed. In this paper, we aim to tackle these research challenges by
developing a novel framework built upon a richer definition of organizational
models coupling resource grouping with process execution knowledge. By
introducing notions of conformance checking for organizational models, the
framework allows effective evaluation of organizational models, and therefore
provides a foundation for analyzing and improving resource grouping based on
event logs. We demonstrate the feasibility of this framework by proposing an
approach underpinned by the framework for organizational model discovery, and
also conduct experiments on real-life event logs to discover and evaluate
organizational models.Comment: Manuscript initially submitted for review on 13/5/2020 with 38 pages,
10 figures, 11 table
Clinical significance of serum lipids in idiopathic pulmonary alveolar proteinosis
<p>Abstract</p> <p>Background</p> <p>It is well known that pulmonary alveolar proteinosis(PAP) is characterised by accumulation of surfactant lipids and proteins within airspaces. However, few previous data describe the serum lipid levels associated with PAP.</p> <p>Materials and methods</p> <p>We retrospectively reviewed 25 patients with idiopathic PAP(iPAP). The serum lipid levels of patients with idiopathic PAP were compared with those of the healthy volunteers. In patients and healthy subjects, the LDL-C/HDL-C ratios were 2.94 ± 1.21 and 1.60 ± 0.70, respectively (<it>p </it>< 0.001), HDL-C were 1.11 ± 0.27 and 1.71 ± 0.71 respectively (<it>p </it>< 0.001). The values of LDL-C correlated significantly with those of PaO2 and P<sub>A-a</sub>O2 (r = -0.685, <it>p </it>= 0.003, and r = 0.688, <it>p </it>= 0.003, respectively). The values of LDL-C/HDL-C ratios also correlated with PaO2 levels and PA-aO2 levels (r = -0.698, p = 0.003, and r = 0.653, p = 0.006, respectively). 11 and 13 patients experienced respectively a decline in TC and LDL-C levels following whole lung lavage(WLL), the median decline was 0.71 mmol/L(<it>p </it>< 0.009) and 0.47 mmol/L(<it>p </it>< 0.003), respectively.</p> <p>Conclusions</p> <p>the serum lipid levels, especially the levels of LDL-C and LDL-C/HDL-C, may reflect the severity of the disease in PAP patients, and predict the therapeutic effect of WLL.</p
Flexural strength of special reinforced lightweight concrete beam for Industrialised Building System (IBS)
Special reinforced lightweight aggregate concrete (SRLWAC) beam is designed as beam component in Industrialised Building System (IBS). It is used to overcome the difficulties during the component installation due to the heavy lifting task. This paper presents the flexural strength and performance of SRLWAC beam under vertical static load. SRLWAC beam was set-up on two columns corbel and tested under monotonic vertical load. Five Linear Variable Displacement Transducers (LVDTs) were instrumented in the model to record displacement. The ultimate flexural capacity of the beam was obtained at the end of experiment where failure occurred. Performance of the beam was evaluated in load-displacement relationship of beam and mode of failure. SRLWAC beam was then modelled and simulated by nonlinear finite element software- Autodesk Simulation Mechanical. Result from finite element analysis was verified by experimental result. Maximum mid-span displacement, Von-Mises stress, concrete maximum principal stress, and yielding strength of reinforcement were discussed in this paper. The beam was behaved elastically up to 90 kN and deformed plastically until ultimate capacity of 250.1 kN in experimental test. The maximum mid span displacement for experimental and simulation were 15.21 mm and 15.36 mm respectively. The major failure of IBS SRLWAC beam was the splitting of the concrete and yielding of main reinforcements at overlay end. Ductility ratio of IBS SRLWAC beam was 14.2, which was higher than pre-stressed concrete beam
Goldstone Fermion Dark Matter
We propose that the fermionic superpartner of a weak-scale Goldstone boson
can be a natural WIMP candidate. The p-wave annihilation of this `Goldstone
fermion' into pairs of Goldstone bosons automatically generates the correct
relic abundance, whereas the XENON100 direct detection bounds are evaded due to
suppressed couplings to the Standard Model. Further, it is able to avoid
indirect detection constraints because the relevant s-wave annihilations are
small. The interactions of the Goldstone supermultiplet can induce non-standard
Higgs decays and novel collider phenomenology.Comment: 25 pages, 6 figures. References added, minor typos corrected.
Submitted to JHE
Effects of Triterpenoid Glycosides from Fresh Ginseng Berry on SW480 Human Colorectal Cancer Cell Line
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