2,379 research outputs found

    Suspension and Measurement of Graphene and Bi2Se3 Atomic Membranes

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    Coupling high quality, suspended atomic membranes to specialized electrodes enables investigation of many novel phenomena, such as spin or Cooper pair transport in these two dimensional systems. However, many electrode materials are not stable in acids that are used to dissolve underlying substrates. Here we present a versatile and powerful multi-level lithographical technique to suspend atomic membranes, which can be applied to the vast majority of substrate, membrane and electrode materials. Using this technique, we fabricated suspended graphene devices with Al electrodes and mobility of 5500 cm^2/Vs. We also demonstrate, for the first time, fabrication and measurement of a free-standing thin Bi2Se3 membrane, which has low contact resistance to electrodes and a mobility of >~500 cm^2/Vs

    Dirac Equation at Finite Temperature

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    In this paper, we propose finite temperature Dirac equation, which can describe the quantum systems in an arbitrary temperature for a relativistic particle of spin-1/2. When the temperature T=0, it become Dirac equation. With the equation, we can study the relativistic quantum systems in an arbitrary temperature.Comment: arXiv admin note: text overlap with arXiv:1005.2751, arXiv:hep-ph/0004125, arXiv:hep-ph/0005272 by other author

    A mutation in Arabidopsis SAL1 alters its in vitro activity against IP3 and delays developmental leaf senescence in association with lower ROS levels

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    Key message: Our manuscript is the first to find a link between activity of SAL1/OLD101 against IP 3 and plant leaf senescence regulation and ROS levels assigning a potential biological role for IP 3. Abstract: Leaf senescence is a genetically programmed process that limits the longevity of a leaf. We identified and analyzed the recessive Arabidopsis stay-green mutation onset of leaf death 101 (old101). Developmental leaf longevity is extended in old101 plants, which coincided with higher peroxidase activity and decreased H 2O 2 levels in young 10-day-old, but not 25-day-old plants. The old101 phenotype is caused by a point mutation in SAL1, which encodes a bifunctional enzyme with inositol polyphosphate-1-phosphatase and 3′ (2′), 5′-bisphosphate nucleotidase activity. SAL1 activity is highly specific for its substrates 3-polyadenosine 5-phosphate (PAP) and inositol 1, 4, 5-trisphosphate (IP 3), where it removes the 1-phosphate group from the IP 3 second messenger. The in vitro activity of recombinant old101 protein against its substrate IP 3 was 2.5-fold lower than that of wild type SAL1 protein. However, the in vitro activity of recombinant old101 mutant protein against PAP remained the same as that of the wild type SAL1 protein. The results open the possibility that the activity of SAL1 against IP 3 may affect the redox balance of young seedlings and that this delays the onset of leaf senescence

    OrgMining 2.0: A Novel Framework for Organizational Model Mining from Event Logs

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    Providing appropriate structures around human resources can streamline operations and thus facilitate the competitiveness of an organization. To achieve this goal, modern organizations need to acquire an accurate and timely understanding of human resource grouping while faced with an ever-changing environment. The use of process mining offers a promising way to help address the need through utilizing event log data stored in information systems. By extracting knowledge about the actual behavior of resources participating in business processes from event logs, organizational models can be constructed, which facilitate the analysis of the de facto grouping of human resources relevant to process execution. Nevertheless, open research gaps remain to be addressed when applying the state-of-the-art process mining to analyze resource grouping. For one, the discovery of organizational models has only limited connections with the context of process execution. For another, a rigorous solution that evaluates organizational models against event log data is yet to be proposed. In this paper, we aim to tackle these research challenges by developing a novel framework built upon a richer definition of organizational models coupling resource grouping with process execution knowledge. By introducing notions of conformance checking for organizational models, the framework allows effective evaluation of organizational models, and therefore provides a foundation for analyzing and improving resource grouping based on event logs. We demonstrate the feasibility of this framework by proposing an approach underpinned by the framework for organizational model discovery, and also conduct experiments on real-life event logs to discover and evaluate organizational models.Comment: Manuscript initially submitted for review on 13/5/2020 with 38 pages, 10 figures, 11 table

    Clinical significance of serum lipids in idiopathic pulmonary alveolar proteinosis

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    <p>Abstract</p> <p>Background</p> <p>It is well known that pulmonary alveolar proteinosis(PAP) is characterised by accumulation of surfactant lipids and proteins within airspaces. However, few previous data describe the serum lipid levels associated with PAP.</p> <p>Materials and methods</p> <p>We retrospectively reviewed 25 patients with idiopathic PAP(iPAP). The serum lipid levels of patients with idiopathic PAP were compared with those of the healthy volunteers. In patients and healthy subjects, the LDL-C/HDL-C ratios were 2.94 ± 1.21 and 1.60 ± 0.70, respectively (<it>p </it>< 0.001), HDL-C were 1.11 ± 0.27 and 1.71 ± 0.71 respectively (<it>p </it>< 0.001). The values of LDL-C correlated significantly with those of PaO2 and P<sub>A-a</sub>O2 (r = -0.685, <it>p </it>= 0.003, and r = 0.688, <it>p </it>= 0.003, respectively). The values of LDL-C/HDL-C ratios also correlated with PaO2 levels and PA-aO2 levels (r = -0.698, p = 0.003, and r = 0.653, p = 0.006, respectively). 11 and 13 patients experienced respectively a decline in TC and LDL-C levels following whole lung lavage(WLL), the median decline was 0.71 mmol/L(<it>p </it>< 0.009) and 0.47 mmol/L(<it>p </it>< 0.003), respectively.</p> <p>Conclusions</p> <p>the serum lipid levels, especially the levels of LDL-C and LDL-C/HDL-C, may reflect the severity of the disease in PAP patients, and predict the therapeutic effect of WLL.</p

    Flexural strength of special reinforced lightweight concrete beam for Industrialised Building System (IBS)

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    Special reinforced lightweight aggregate concrete (SRLWAC) beam is designed as beam component in Industrialised Building System (IBS). It is used to overcome the difficulties during the component installation due to the heavy lifting task. This paper presents the flexural strength and performance of SRLWAC beam under vertical static load. SRLWAC beam was set-up on two columns corbel and tested under monotonic vertical load. Five Linear Variable Displacement Transducers (LVDTs) were instrumented in the model to record displacement. The ultimate flexural capacity of the beam was obtained at the end of experiment where failure occurred. Performance of the beam was evaluated in load-displacement relationship of beam and mode of failure. SRLWAC beam was then modelled and simulated by nonlinear finite element software- Autodesk Simulation Mechanical. Result from finite element analysis was verified by experimental result. Maximum mid-span displacement, Von-Mises stress, concrete maximum principal stress, and yielding strength of reinforcement were discussed in this paper. The beam was behaved elastically up to 90 kN and deformed plastically until ultimate capacity of 250.1 kN in experimental test. The maximum mid span displacement for experimental and simulation were 15.21 mm and 15.36 mm respectively. The major failure of IBS SRLWAC beam was the splitting of the concrete and yielding of main reinforcements at overlay end. Ductility ratio of IBS SRLWAC beam was 14.2, which was higher than pre-stressed concrete beam

    Goldstone Fermion Dark Matter

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    We propose that the fermionic superpartner of a weak-scale Goldstone boson can be a natural WIMP candidate. The p-wave annihilation of this `Goldstone fermion' into pairs of Goldstone bosons automatically generates the correct relic abundance, whereas the XENON100 direct detection bounds are evaded due to suppressed couplings to the Standard Model. Further, it is able to avoid indirect detection constraints because the relevant s-wave annihilations are small. The interactions of the Goldstone supermultiplet can induce non-standard Higgs decays and novel collider phenomenology.Comment: 25 pages, 6 figures. References added, minor typos corrected. Submitted to JHE
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