43 research outputs found
Prescription of potentially inappropriate medications among older people with intellectual disability: a register study
A comparison of direct analog and digital up-conversion architecture in the frequency range from 1.9 GHz to 2.7 GHz
In this paper the common AUC architecture was compared with the DUC with respect to MER, EVM, output power and power consumption. After a detailed discussion of the theory, the measurement setups were described and afterwards the measurement results discussed. The DUC offers some advantages compared to the AUC. Excellent signal quality can be reached using the digital quadrature modulation. A MER above 46 dB and an EVM below 0.52 % was measured. Fewer parts are needed in comparison with the AUC and the power consumption is nearly equal. In the next years the sampling frequency of DACs will further increase and will make additional frequency ranges accessible to DUC architectures. Therefore DUC is an interesting alternative for new transmitter designs
Consequences of applying the new EWGSOP2 guideline instead of the former EWGSOP guideline for sarcopenia case finding in older patients
Abstract
Introduction
we examined the consequences of applying the new EWGSOP2 algorithm for sarcopenia screening instead of the former EWGSOP algorithm (EWGSOP1) in geriatric inpatients.
Methods
the dataset of our formerly published Sarcopenia in Geriatric Elderly (SAGE) study includes 144 geriatric inpatients (86 women, 58 men, mean age 80.7±5.6 years) with measurements of gait speed, handgrip strength and appendicular muscle mass by dual x-ray absorptiometry (DXA). We analysed the agreement between EWGSOP and EWGSOP2 algorithms in identifying patients as sarcopenic/non-sarcopenic. Differences in the distribution sarcopenic vs. non-sarcopenic were assessed by Chi²-test.
Results
sarcopenia prevalence according to EWGSOP1 (41 (27.7%)) was significantly higher than with EWGSOP2 (26(18.1%), p<0.05). The sex-specific sarcopenia prevalence was 22.1% (EWGSOP1) and 17.4% (EWGSOP2), respectively, for women (difference not significant) and 37.9% vs. 19.4% for men (p<0.05%). The overall agreement in classifying subjects as sarcopenic/non-sarcopenic was 81.25% (81.4% for women, 81.0% for men). However, among the 41 sarcopenia cases identified by EWGSOP1, only 20 (48.8%) were diagnosed with sarcopenia by EWGSOP2 (9/19 w (47.4%), 11/22 m (50.0%)). Ten of 19 women (52.6%) and 11 of 22 men (50.0%) diagnosed with sarcopenia by EWGSOP1 were missed by EWGSOP2, while 6 of 15 women (40.0%) and 0 of 11 men (0.0%) were newly diagnosed.
Discussion
there is a substantial mismatch in sarcopenia case finding according to EWGSOP1 and EWGSOP2. The overall prevalence and the number of men diagnosed with sarcopenia are significantly lower in EWGSOP2. While the absolute number of women identified as sarcopenic remains relatively constant, the overlap of individual cases between the two definitions is low.
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