Does Ozone Administration Have a Protective Effect Against Cisplatininduced Histological Changes in Rat Testis?

Objective:We investigated the protective and therapeutic effects of ozone therapy (OT) on cisplatin (CP)-induced testicular damage.Materials and Methods:Thirty healthy adult male Wistar rats were divided into five groups consisting of 6 animals each: 1) control, 2) CP, 3) OT, 4) OT + CP and 5) CP + OT groups. Histopathological findings, Johnsen scores, thiobarbituric acid-reactive substances (TBARS), glutathione (GSH), superoxide dismutase (SOD), catalase, and GSH peroxidase (GPx) levels were evaluated.Results:CP caused a significant decrease in testicular weight and Johnsen score compared to the control group. In addition, TBARS level was significantly higher, whereas GSH, SOD, catalase and GPx levels were significantly lower in the CP group when compared to the control group. Pre- and post-CP OT significantly increased GSH, SOD, catalase and GPx levels and decreased TBARS level. Also, testicular weight and Johnsen score were increased with OT.Conclusion:The present study showed that OT is protective against CP-induced testicular damage. OT may be beneficial to patients who underwent CP chemotherapy

Delayed and Incidental Diagnosis of Transverse Testicular Ectopia

Transverse testicular ectopia is a rare malformation in which both testes are placed in the same inguinal region. Most of the patients are diagnosed incidentally during inguinal exploration. We here report three cases of transverse testicular ectopia and discuss the causes of delayed and incidental diagnosis of this infrequent malformation. Although the mean age at presentation was reported as 4 years, the mean age of our patients was 7.7 months. We detected the contralateral testis in the inguinal canal in all of our patients preoperatively. The most important diagnostic criteria are to be aware of this rare malformation and getting suspicious in patients with one side inguinal hernia and an empty hemiscrotum on the other side. It is essential to perform an ultrasound scan in patients with such a clinical presentation

A Rare Case of Septic Shock in an Adolescent: Rectal Perforation Resulting from a Fall from a Hammock

Anorectal injuries are rarely seen in children. These injuries may sometimes lead to peritoneal contamination and result in severe clinical manifestations. Herein, we present a 14-year-old male patient who presented with symptoms of septic shock and was diagnosed with rectal perforation occurring after a fall from a hammock. The patient underwent sigmoid colostomy. In order to decrease the morbidity and mortality from anorectal traumas, an early and accurate diagnosis as well as detection and treatment of additional organ injuries are required. Therefore, atypical presentations should be born in mind. (The Me­di­cal Bul­le­tin of Ha­se­ki 2014; 52: 133-6

Two cases of infantile myofibromatosis: Multiple visceral involvement and a solitary soft tissue mass

Infantile myofibromatosis is a rare myofibroblastic tumor in which soft tissue, bone and rarily visceral involvement can be seen. It is usually a solitary tumor, however, multicentric involvement may also be present. The cases with solitary or multiple lesions but no visceral involvement have good prognosis and spontaneous regression can often be seen. Nevertheless, multicentric visceral tumors are associated with high mortality. In this report, imaging findings of a case of infantile myofibromatosis with liver and both adrenal glands involvement; and another case with involvement of posterior thoracal and servical region muscles are presented

The all-seeing needle instead of the veress needle in pediatric urologic laparoscopy

WOS: 000326970200011PubMed ID: 23560687Purpose: To investigate the feasibility of the all-seeing needle for safe entry and creation of pneumoperitoneum in pediatric urologic laparoscopy. Patients and Methods: A total of 14 children underwent various transperitoneal urologic laparoscopic procedures. The all-seeing needle, which is 4.85F in diameter, was used for safe entry into the abdominal cavity at the site of the umblicus in all cases. The microoptic was integrated with the light system and connected via a zoom ocular enabling direct visualization of the layers between the skin and the peritoneal cavity. Once the intraperitoneal access was obtained, CO2 pneumoperitoneum was created from one port of the three-way connector attached to the proximal part of the needle. Then the laparoscopic trocars were placed under vision of the microoptical system. Results: Mean age of the children was 4.52.9 years. In all children, the all-seeing needle was safely introduced into the abdominal cavity under direct vision. Then, CO2 pneumoperitoneum was succesfully performed. The mean time for optical puncture was calculated as 1.1 +/- 0.8 minutes. No complication was encountered during the introduction of the needle, creation of the pneumoperitoneum, and placement of the trocars. Conclusions: The all-seeing needle appears to be beneficial in safe entry and for creating pneumoperitoneum in laparoscopic pediatric urology cases. It eliminates the disadvantages of the Veress needle, which is blunt insertion, and may possibly prevent complications