Recovery of wheat heritage for traditional food: genetic variation for high molecular weight glutenin subunits in neglected/underutilized wheat

Club wheat (Triticum aestivum L. ssp. compactum (Host) Mackey), macha wheat (T. aestivum L. ssp. macha (Dekapr. & A.M. Menabde) Mackey) and Indian dwarf wheat (T. aestivum L. ssp. sphaerococcum (Percival) Mackey) are three neglected or underutilized subspecies of hexaploid wheat. These materials were and are used to elaborate modern and traditional products, and they could be useful in the revival of traditional foods. Gluten proteins are the main grain components defining end-use quality. The high molecular weight glutenin subunit compositions of 55 accessions of club wheat, 29 accessions of macha wheat, and 26 accessions of Indian dwarf wheat were analyzed using SDS-PAGE. Three alleles for the Glu-A1 locus, 15 for Glu-B1 (four not previously described), and four for Glu-D1 were detected. Their polymorphisms could be a source of genes for quality improvement in common wheat, which would permit both their recovery as new crops and development of modern cultivars with similar quality characteristics but better agronomic traits

Excited electronic states from a variational approach based on symmetry-projected Hartree--Fock configurations

Recent work from our research group has demonstrated that symmetry-projected Hartree--Fock (HF) methods provide a compact representation of molecular ground state wavefunctions based on a superposition of non-orthogonal Slater determinants. The symmetry-projected ansatz can account for static correlations in a computationally efficient way. Here we present a variational extension of this methodology applicable to excited states of the same symmetry as the ground state. Benchmark calculations on the C$_2$ dimer with a modest basis set, which allows comparison with full configuration interaction results, indicate that this extension provides a high quality description of the low-lying spectrum for the entire dissociation profile. We apply the same methodology to obtain the full low-lying vertical excitation spectrum of formaldehyde, in good agreement with available theoretical and experimental data, as well as to a challenging model $C_{2v}$ insertion pathway for BeH$_2$. The variational excited state methodology developed in this work has two remarkable traits: it is fully black-box and will be applicable to fairly large systems thanks to its mean-field computational cost

Objeto virtual de aprendizaje para la concientización frente a los fenómenos naturales o antrópicos que se suscitan en el departamento de Nariño

La prevención y atención de desastres es una temática de interés general. En el caso particular del departamento de Nariño son diversas las amenazas a las cuales se encuentra expuesto cada uno de los municipios que lo conforman; por ello, es de gran importancia la implementación de nuevos elementos que contribuyan al conocimiento de los fenómenos que causan estas amenazas, para así contribuir en la gestión del riesgo en toda la comunidad, principalmente en la que se encuentra más vulnerable

On the Nature of the Strong Emission-Line Galaxies in Cluster Cl 0024+1654: Are Some the Progenitors of Low Mass Spheroidals?

We present new size, line ratio, and velocity width measurements for six strong emission-line galaxies in the galaxy cluster, Cl 0024+1654, at redshift z~0.4. The velocity widths from Keck spectra are all narrow (30<sigma<120 km/s), with three profiles showing double peaks. Four galaxies have low masses (M<10^{10} Mo). Whereas three galaxies were previously reported to be possible AGNs, none exhibit AGN-like emission line ratios or velocity widths. Two or three appear as very blue spirals with the remainder more akin to luminous H-II galaxies undergoing a strong burst of star formation. We propose that after the burst subsides, these galaxies will transform into quiescent dwarfs, and are thus progenitors of some cluster spheroidals (We adopt the nomenclature suggested by Kormendy & Bender (1994), i.e., low-density, dwarf ellipsoidal galaxies like NGC 205 are called `spheroidals' instead of `dwarf ellipticals') seen today.Comment: 14 pages + 2 figures + 1 table, LaTeX, Acc. for publ. in ApJL also available at http://www.ucolick.org/~deep/papers/papers.htm

Cáncer gástrico

ResumenEl cáncer gástrico (CG) mantiene alta prevalencia en Chile, con una tasa de mortalidad de 20/100.000 habitantes. Se reconocen dos variantes histológicas, el tipo difuso y el tipo intestinal. El primero crece en forma de células sueltas y el segundo forma glándulas semejantes a las intestinales. Para el intestinal, la histogénesis se inicia con una gastritis atrófica, seguida de metaplasia, displasia y cáncer a diferencia del difuso cuya histogénesis es diferente, en mucosa fúndica. Ambos pueden presentarse combinados, en ambos se reconoce asociación con el Helicobacter Pylori y otros factores ambientales, pero el de tipo intestinal es el más caracteristico de áreas de alta incidencia y el difuso tiene una vertiente más asociada a factores hereditarios. Además, entre ambos existen diferencias de comportamiento clinico. La clasificación de origen japonés en cáncer incipiente y avanzado mantiene utilidad por su trascendencia pronóstica y terapéutica. Para la etapificación clinica (c) y patológica (p)se ha universalizado el sistema TNM. Los sintomas son inespecificos y sugieren una enfermedad avanzada. Esto justifica politicas de prevención, el reconocimiento de factores de riesgo y la endoscopía con biopsia aun ante síntomas sutiles. La etapificación clínica y el tratamiento se definen en comité multidisciplinario. La tomografía de tórax, abdomen y pelvis es el examen inicial y se complementa según necesidad y disponibilidad. Para el tratamiento no existe un procedimiento estándar Para tumores T1a se considera la resección endoscópica y para los avanzados, la resección quirúrgica tipo D2- RO. Esta puede hacerse por vía abierta o laparoscópica. Para tumores avanzados o con compromiso ganglionar se indica neoadyuvancia o adyuvancia. En algunos pacientes el tratamiento solo tiene objetivos paliativos.SummaryGastric Cancer (GC) is highly prevalent in Chile, with a mortality rate of 20/100.000 inhabitants. Two histological entities are recognized: diffuse type (isolated tumoral cells) and intestinal type (intestinal-like glandular structures). For the latter the sequence of atrophy, metaplasia, displasia and progression to cancer is recognized whereas the diffuse type grows mainly in fundic mucosa. Both may present combined, and both have carcinogenetic association with Helicobacter Pylori. The intestinal type is characteristic for high risk areas whereas the diffuse type has been associated more frequently with genetic-hereditary predisposition. The Japanese classification of early and advanced GC mantains therapeutic and prognostic value. For clinical (c) and patological (p) staging the TNM system is of generalized use. Symptoms are non specific, and suggest an advanced disease. Therefore strategies for prevention in high risk areas must be designed. Clinical awareness, the recognition of risk factors, and early endoscopy with biopsy may be helpful for an early diagnosis. Individual staging and treatment are mutidisciplinary. Computed tomography of the chest, abdomen and pelvis is complemented by other studies according to individual indication. Treatment should be individually tailored. For Tla tumors endoscopic treatment is available with excellent results but with follow-up commitment. For advanced localized tumors D2-R0 resection is indicated. Neo adyuvant or adyuvant treatment should be considered in these patients. Some patients with diseminated disease only allow palliative treatment

Casimir torque

We develop a formalism for the calculation of the flow of angular momentum carried by the fluctuating electromagnetic field within a cavity bounded by two flat anisotropic materials. By generalizing a procedure employed recently for the calculation of the Casimir force between arbitrary materials, we obtain an expression for the torque between anisotropic plates in terms of their reflection amplitude matrices. We evaluate the torque in 1D for ideal and realistic model materials.Comment: 8 pages, 4 figs, Submitted to Proc. of QFEXT'05, to appear in J. Phys.

Shilajit: A Natural Phytocomplex with Potential Procognitive Activity

Shilajit is a natural substance found mainly in the Himalayas, formed for centuries by the gradual decomposition of certain plants by the action of microorganisms. It is a potent and very safe dietary supplement, restoring the energetic balance and potentially able to prevent several diseases. Recent investigations point to an interesting medical application toward the control of cognitive disorders associated with aging, and cognitive stimulation. Thus, fulvic acid, the main active principle, blocks tau self-aggregation, opening an avenue toward the study of Alzheimer's therapy. In essence, this is a nutraceutical product of demonstrated benefits for human health. Considering the expected impact of shilajit usage in the medical field, especially in the neurological sciences, more investigations at the basic biological level as well as clinical trials are necessary, in order to understand how organic molecules of shilajit and particularly fulvic acid, one of the active principles, and oligoelements act at both the molecular and cellular levels and in the whole organism

Social media brand engagement in the context of collaborative consumption: the case of AIRBNB

This study focuses on social media brand engagement in the context of shared and collaborative consumption businesses, a novel trend in the hospitality industry. By drawing on the concept of brands being defined collectively through an assemblage of heterogonous human and nonhuman actors, and focusing on the brand Airbnb—a peer-to-peer online platform for renting, swapping, and lending accommodations—the current study examines how consumers’ perceptions of Airbnb brand equity mediate the relationship between functional and hedonic brand image and social media behavioral engagement in terms of consumption, contribution, and creation of brand-related content (COBRAs). Results discriminate between direct and indirect effects. Findings reveal that hedonic brand image directly influences behavioral engagement on social media, whereas brand equity fully mediates the relationship between functional brand image and COBRAs. Implications for theory and practice related to shared or collaborative consumption platforms in the hospitality industry are discussed and suggestions for future studies are presented. This research paper provides conceptual and theoretical clarity on issues such as how consumers’ brand perceptions influence their behavioral engagement on social media.info:eu-repo/semantics/acceptedVersio

A matheuristic approach combining genetic algorithm and mixed integer linear programming model for production and distribution planning in the supply chain

[EN] A number of research studies has addressed supply chain planning from various perspectives (strategical, tactical, operational) and demonstrated the advantages of integrating both production and distribution planning (PDP). The globalisation of supply chains and the fourth industrial revolution (Industry 4.0) mean that companies must be more agile and resilient to adapt to volatile demand, and to improve their relation with customers and suppliers. Hence the growing interest in coordinating production-distribution processes in supply chains. To deal with the new market¿s requirements and to adapt business processes to industry¿s regulations and changing conditions, more efforts should be made towards new methods that optimise PDP processes. This paper proposes a matheuristic approach for solving the PDP problem. Given the complexity of this problem, combining a genetic algorithm and a mixed integer linear programming model is proposed. The matheuristic algorithm was tested using the Coin-OR Branch & Cut open-source solver. The computational outcomes revealed that the presented matheuristic algorithm may be used to solve real sized problems.This work was supported by the Conselleria de Educación, Investigación, Cultura y Deporte - Generalitat Valenciana for hiring predoctoral research staff with Grant (ACIF/2018/170) and European Social Fund with Grant Operational Program of FSE 2014-2020, the Valencian Community. The research leading to these results received funding from the European Union H2020 Programme with grant agreement No. 958205 "Industrial Data Services for Quality Control in Smart Manufacturing" (i4Q) and the Regional Department of Innovation, Universities, Science and Digital Society of the Generalitat Valenciana entitled "Industrial Production and Logistics Optimization in Industry 4.0" (i4OPT) (Ref. PROMETEO/ 2021/065)Guzmán-Ortiz, BE.; Poler, R.; Andres, B. (2023). A matheuristic approach combining genetic algorithm and mixed integer linear programming model for production and distribution planning in the supply chain. Advances in Production Engineering & Management. 18(1):19-31. https://doi.org/10.14743/apem2023.1.454193118