465 research outputs found

    Chayene, de Sobradinho para o mundo: identidade cultural na pós-modernidade

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    RESUMO   Esta pesquisa analisa a forma como o sujeito pós-moderno e sua identidade cultural são representados pela personagem Chayene, antagonista da telenovela “Cheias de Charme”, exibida pela Rede Globo. A telenovela brasileira, caracterizada pela estreita relação que mantem com a realidade sociocultural do país, introduziu em seu expediente a transitoriedade da construção identitária dos sujeitos. Por essa razão, se apresenta como bom laboratório para analisar questões relacionadas à diferenciação, hibridização e multiculturalismo.   Palavras-chave: Telenovela; Identidade Cultural; Piauí; Chayene   RESUMEN   Esta investigación examina cómo el sujeto posmoderno y su identidad cultural está representada por el personaje Chayene, antagonista de la telenovela  "Cheia de Charme", transmitida por la Red Globo. La telenovela brasileña, que se caracteriza por mantener una estrecha colaboración con la realidad socio-cultural del país, presentó en su trama la fugacidad de la construcción de la identidad del sujeto. Por este motivo, aparece como buen laboratorio para analizar los temas relacionados con la diferenciación, la hibridación y la multiculturalidad.   Palavras-clave: Telenovela; Identidad Cultural; Piauí; Chayene   ABSTRACT   This research examines how the postmodern subject and its cultural identity are represented by Chayene, which is an antagonist character of a brazilian soap opera named “Cheias de Charme”, broadcasted by Globo Television Network.  The brazilian soap opera has a profound relationship  with socio-cultural context of the country and shows how transient is the construction of the subject´s identity. For this reason, it seems to be a good laboratory to analyze issues related to differentiation, hybridization and multiculturalism.   Keywords: Soap opera; Cultural Identity; Piauí; Chayene

    SUSTENTABILIDADE E VALOR DE MERCADO: ESTUDO DE EVENTOS RELATIVOS À PARTICIPAÇÃO NO ÍNDICE DE SUSTENTABILIDADE EMPRESARIAL

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    Tendo como base o estudo do Indice de Responsabilidade Empresarial (ISE) da Bolsa de São Paulo, o objetivo geral desta dissertação consistiu-se em avaliar se eventos relativos à participação no Índice de Sustentabilidade Empresarial influenciam no valor de mercado. Em termos metodológicos, foi realizada uma pesquisa causal, recorrendo-se a um estudo comparativo, com abordagem quantitativa. Os dados foram coletados em demonstrações financeiras, pelo software Economática®, do site da BM&FBovespa. A análise dos dados foi realizada pela técnica de estudo de eventos, de forma a identificar se a divulgação da entrada ou da saída do ISE influencia de forma significativa os preços das ações. Pode ser constatado que os desempenhos empresariais das organizações que adotam práticas de responsabilidade social apresentam índices positivos, influenciando diretamente nos rendimentos líquidos apurados. Como resultados o fato das empresas terem sua atuação nas áreas sociais e ambientais, reconhecida e divulgada, influenciaria positivamente o seu desempenho financeiro

    Relationship among malocclusion, number of occlusal pairs and mastication

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    This study evaluated the relationship among malocclusion, number of occlusal pairs, masticatory performance, masticatory time and masticatory ability in completely dentate subjects. Eighty healthy subjects (mean age = 19.40 ± 4.14 years) were grouped according to malocclusion diagnosis (n = 16): Class I, Class Class II-2, Class III and Normocclusion (control). Number of occlusal pairs was determined clinically. Masticatory performance was evaluated by the sieving method, and the time used for the comminute test food was registered as the masticatory time. Masticatory ability was measured by a dichotomic self-perception questionnaire. Statistical analysis was done by one-way ANOVA, ANOVA on ranks, Chi-Square and Spearman tests. Class II-1 and III malocclusion groups presented a smaller number of occlusal pairs than Normocclusion (p < 0.0001), Class I (p < 0.001) and II-2 (p < 0.0001) malocclusion groups. Class I, and III malocclusion groups showed lower masticatory performance values compared to Normocclusion (p < 0.05) and Class II-2 (p < 0.05) malocclusion groups. There were no differences in masticatory time (p = 0.156) and ability (&#967;2 = 3.58/p= 0.465) among groups. Occlusal pairs were associated with malocclusion (rho = 0.444/p < 0.0001) and masticatory performance (rho = 0.393/p < 0.0001), but malocclusion was not correlated with masticatory performance (rho = 0.116/p= 0.306). In conclusion, masticatory performance and ability were not related to malocclusion, and subjects with Class I, II-1 and III malocclusions presented lower masticatory performance because of their smaller number of occlusal pairs

    Solid waste management: a case study in a hospital institution in Belo Horizonte – MG

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    With the technological advances and the increase of the competitiveness emerges the need, both legal and social, of the companies to discard their waste correctly, attending not only to the requirements for its operation, but also the demands of the market. In this aspect, the main objective of this research was to analyze the solid waste management according to the perception of managers who work in a hospital organization, located in the metropolitan region of Minas Gerais. The methodological approach was guided by a qualitative and descriptive case study in a hospital located in the state of Minas Gerais. Data were collected through semi-structured interviews, based on a script with fifteen questions, applied to ten managers of the company. The results pointed to the relevance of the organizations being aware of the residues they generate, regardless of their degree of hazard, and it is important to practice efficient methods with the objective of smoothing the negative impacts generated by the waste released to the environment. Thus, effective segregation as well as methods of care that seek to reduce the volume of waste to be deposited in the soil and reported to the community is an important code to be followed. It was also observed that the recycling of the materials allows an increase of revenue, as well as a reduction of costs, because when a material is recycled one does not have the costs with the disposal of such materials

    Influence of carbonation on the chloride ion diffusion coefficient in fly ash concrete

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    The incorporation of fly ash (FA) in cementitious matrices has been frequently used in order to make the matrix more resistant to the action of chlorides. On the other hand, it is known that Ca(OH)2 existing in the matrix is consumed by the pozzolanic reactions, which makes easier the carbonation front advance. Given that the chloride ingress and carbonation are the two main causes of degradation in reinforced concrete, we speculate about the behaviour of FA concrete when the structure is submitted simultaneously to chlorides and carbonation. This work studied the influence of carbonation on the chloride migration coefficient in FA concrete. For this, specimens with 0% and 40% replacement of cement CEM I 42.5R by FA were casted with water/binder 0.55 and 0.50 respectively. After 90 days of curing period, half of samples were subjected to accelerated carbonation (20ºC ,55%RH and 4%CO2) for 1, 2 and 3 months. The other half was protected with plastic film during the same period. Non-steady-state migration tests, according to LNEC E463 (Portuguese specification), were performed with specimens subjected to both experimental conditions. The results show that, for these conditions, the carbonation has a direct influence on chloride diffusion coefficient, increasing it. For FA concrete samples this effect is more evident. In these cases, the carbonated samples studied showed a diffusion coefficient up to two times higher than noncarbonated ones. The increase in large capillary pores, caused by carbonation, can be responsible for the increase of chloride penetration into concrete subjected to combined actio

    Fitotoxicidade na cultura de soja causada por deriva simulada de dicamba

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    The objective of this work was to evaluate injury symptoms on soybean not tolerant to dicamba (3,6-dichloro-2-methoxybenzoic acid), as well as crop yield, after the application of sub-rates of the herbicide to simulate physical drift in tropical conditions. Dicamba rates of 0, 5.8, 14.4, 28.8, 57.6, and 576 g acid equivalent per hectare were applied at the vegetative (V3) and reproductive (R1) stages of soybean, using a backpack sprayer pressurized with CO2, equipped with air-induction flat fan spray nozzles; the pressure and rate of application were 250 kPa and 200 L ha-1, respectively. Visible injury, the soil-plant analysis development (SPAD) index (leaf chlorophyll content) at 14 days after herbicide application, and soybean crop yield were evaluated. These variables were influenced by the crop stage in which the dicamba rates were applied. Rates below 28.8 g ha-1 caused less injury to soybean when applied at the R1 stage; however, there were no differences in yield between stages. A 1% dicamba drift in tropical conditions reduces soybean yield by 12%.O objetivo deste trabalho foi avaliar os sintomas de injúria em soja não tolerante ao dicamba (ácido 3,6-dicloro-2-metoxibenzóico), bem como a produtividade da cultura, após a aplicação de subdoses do herbicida para simulação da deriva física em condições tropicais. Doses de dicamba de 0, 5,8, 14,4, 28,8, 57,6 e 576 g de equivalente ácido por hectare foram aplicadas nos estádios vegetativo (V3) e reprodutivo (R1) da soja, com uso de pulverizador costal acionado por CO2, dotado de pontas de jato plano com indução de ar; a pressão e a taxa de aplicação foram de 250 kPa e 200 L ha-1, respectivamente. Foram avaliados injúria visual, índice “soil-plant analysis development” (SPAD) (teor de clorofila das folhas) aos 14 dias após a aplicação do herbicida e produtividade da cultura de soja. Essas variáveis foram influenciadas pelo estádio da cultura em que as doses de dicamba foram aplicadas. Doses inferiores a 28,8 g ha-1 causaram menor injúria na soja quando aplicadas no estádio R1; contudo, não houve diferenças de produtividade entre os estádios. A deriva de dicamba de 1%, em condições tropicais, reduz a produtividade da soja em 12%

    Bowman-Birk protease inhibitor from Vigna unguiculata seeds enhances the action of bradykinin-related peptides

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    The hydrolysis of bradykinin (Bk) by different classes of proteases in plasma and tissues leads to a decrease in its half-life. Here, Bk actions on smooth muscle and in vivo cardiovascular assays in association with a protease inhibitor, Black eyed-pea trypsin and chymotrypsin inhibitor (BTCI) and also under the effect of trypsin and chymotrypsin were evaluated. Two synthetic Bk-related peptides, Bk1 and Bk2, were used to investigate the importance of additional C-terminal amino acid residues on serine protease activity. BTCI forms complexes with Bk and analogues at pH 5.0, 7.4 and 9.0, presenting binding constants ranging from 103 to 104 M−1. Formation of BTCI-Bk complexes is probably driven by hydrophobic forces, coupled with slight conformational changes in BTCI. In vitro assays using guinea pig (Cavia porcellus) ileum showed that Bk retains the ability to induce smooth muscle contraction in the presence of BTCI. Moreover, no alteration in the inhibitory activity of BTCI in complex with Bk and analogous was observed. When the BTCI and BTCI-Bk complexes were tested in vivo, a decrease of vascular resistance and consequent hypotension and potentiating renal and aortic vasodilatation induced by Bk and Bk2 infusions was observed. These results indicate that BTCI-Bk complexes may be a reliable strategy to act as a carrier and protective approach for Bk-related peptides against plasma serine proteases cleavage, leading to an increase in their half-life. These findings also indicate that BTCI could remain stable in some tissues to inhibit chymotrypsin or trypsin-like enzymes that cleave and inactivate bradykinin in situ

    Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?

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    Background: Exosomes isolated from plasma of patients with sepsis may induce vascular apoptosis and myocardial dysfunction by mechanisms related to inflammation and oxidative stress. Despite previous studies demonstrating that these vesicles contain genetic material related to cellular communication, their molecular cargo during sepsis is relatively unknown. In this study, we evaluated the presence of microRNAs (miRNAs) and messenger RNAs (mRNAs) related to inflammatory response and redox metabolism in exosomes of patients with septic shock. Methods: Blood samples were collected from 24 patients with septic shock at ICU admission and after 7 days of treatment. Twelve healthy volunteers were used as control subjects. Exosomes were isolated by ultracentrifugation, and their miRNA and mRNA content was evaluated by qRT-PCR array. Results: As compared with healthy volunteers, exosomes from patients with sepsis had significant changes in 65 exosomal miRNAs. Twenty-eight miRNAs were differentially expressed, both at enrollment and after 7 days, with similar kinetics (18 miRNAs upregulated and 10 downregulated). At enrollment, 35 differentially expressed miRNAs clustered patients with sepsis according to survival. The pathways enriched by the miRNAs of patients with sepsis compared with control subjects were related mostly to inflammatory response. The comparison of miRNAs from patients with sepsis according to hospital survival demonstrated pathways related mostly to cell cycle regulation. At enrollment, sepsis was associated with significant increases in the expression of mRNAs related to redox metabolism (myeloperoxidase, 64-foldPRDX3, 2.6-foldSOD2, 2.2-fold) and redox-responsive genes (FOXM1, 21-foldSELS, 16-foldGLRX2, 3.4-fold). The expression of myeloperoxidase mRNA remained elevated after 7 days (65-fold). Conclusions: Exosomes from patients with septic shock convey miRNAs and mRNAs related to pathogenic pathways, including inflammatory response, oxidative stress, and cell cycle regulation. Exosomes may represent a novel mechanism for intercellular communication during sepsis.Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)Research and Education Institute, Hospital Sirio-LibanesHosp Sirio Libanes, Res & Educ Inst, Rua Prof Daher Cutait 69, BR-01539001 Sao Paulo, SP, BrazilUniv Sao Paulo, Sao Paulo State Canc Inst, Sao Paulo, BrazilHosp Serv Publ Estadual Sao Paulo, Sao Paulo, BrazilUniv Fed Minas Gerais, Inst Ciencias Biol, Morphol Dept, Belo Horizonte, MG, BrazilUniv Sao Paulo, Sch Med, Heart Inst, Lab Immunol, Sao Paulo, BrazilUniv Estadual Paraiba, Ctr Ciencias & Tecnol, Campina Grande, BrazilLudwig Inst Canc Res, Sao Paulo, BrazilAC Camargo Canc Ctr, Int Res Ctr, Sao Paulo, BrazilUniv Sao Paulo, Sch Med, Div Clin Immunol & Allergy, Sao Paulo, BrazilUniv Fed Sao Paulo, Sao Paulo, BrazilUniv Sao Paulo, Emergency Med, Sao Paulo, BrazilUniv Fed Sao Paulo, Sao Paulo, BrazilFAPESP: 10/52554-1Web of Scienc

    Caracterização da violência sofrida por mulheres da zona rural de um Estado Brasileiro

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    Violence is present in many realities and social groups. Therefore, this study seeks to characterize violence against women living in rural Minas Gerais.  A descriptive epidemiological study was conducted, with secondary data recorded by the Notification Disease Information System (SINAN) from 2008 to 2017. In 2015, it was the year with the highest number of reports of violence against women between 25 and 39 years old (47.8%), black (56.92%) and less educated (40.43%). The victims were assaulted mainly on the face (31.5%), where the aggressor was male (70.41%), and violence was committed at the victim's own residence (81%), without the use of a firearm. In addition, 45% of women reported that violence was recurrent and that in 39% of cases the aggressor used alcohol before the aggression. Most cases of violence against rural residents were psychological and / or moral.A violência está presente em muitas realidades e grupos sociais. Por isso, este estudo busca caracterizar a violência contra as mulheres moradoras de zona rural de Minas Gerais. Foi realizado um estudo epidemiológico descritivo, com dados secundários registrados pelo Sistema de Informação de Agravos de Notificação (SINAN) de 2008 a 2017. Em 2015 foi o ano com o maior número de notificações de violência contra mulheres entre 25 e 39 anos (47,8%), negras (56,92%) e menos escolarizadas (40,43%). As vítimas foram agredidas principalmente na face (31,5%), o agressor era do sexo masculino (70,41%), e a violência foi praticada na residência da própria vítima (81%), sem o uso de arma de fogo. Além disso, 45% das mulheres relataram que a violência era recorrente e que em 39% dos casos o agressor fazia uso de álcool antes da agressão. A maioria dos casos de violência contra moradoras rurais foi psicológica e/ou moral
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