Diagnostics of development of a franchise network in the economic system of the region Диагностика развития франчайзинговой сети в экономической системе региона

The article provides main results of the study of theoretical and practical aspects of development of small business in the economic system of the region by means of formation of franchise networks. It develops a theory and methods of selection of the strategy of development of subjects of the small business in the region on the basis of the set goals of entrepreneurial activity, which allows assessment of expediency of creation of franchise networks in the region. The obtained scientific results allow development of activity of representatives of the small business by means of franchise, based on observance of interests of development of economy of each Ukrainian region.В работе изложены основные результаты исследования теоретических и практических аспектов развития малого бизнеса в экономической системе региона путем формирования франчайзинговых сетей. Развита теория и методы выбора стратегии развития субъектов малого бизнеса в регионе на основе поставленных целей предпринимательской деятельности, что позволяет оценить целесообразность создания франчайзинговых сетей в регионе. В совокупности полученные научные результаты позволяют развивать деятельность представителей малого бизнеса средствами франчайзинга, исходя из соблюдения интересов развития экономики каждого региона Украины

High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica

Nephropathia epidemica (NE) is a mild form of hemorrhagic fever with renal syndrome. Several reports have demonstrated a severe alteration in lipoprotein metabolism. However, little is known about changes in circulating lipids in NE. The objectives of this study were to evaluate changes in serum total cholesterol, high density cholesterol (HDCL), and triglycerides. In addition to evaluation of serum cytokine activation associations, changes in lipid profile and cytokine activation were determined for gender, thrombocyte counts, and VEGF. Elevated levels of triglycerides and decreased HDCL were observed in NE, while total cholesterol did not differ from controls. High triglycerides were associated with both the lowest thrombocyte counts and high serum VEGF, as well as a high severity score. Additionally, there were higher levels of triglycerides in male than female NE patients. Low triglycerides were associated with upregulation of IFN-γ and IL-12, suggesting activation of Th1 helper cells. Furthermore, levels of IFN-γ and IL-12 were increased in patients with lower severity scores, suggesting that a Th1 type immune response is playing protective role in NE. These combined data advance the understanding of NE pathogenesis and indicate a role for high triglycerides in disease severity

Slow Spin Relaxation in Two-Dimensional Electron Systems with Antidots

We report a Monte Carlo investigation of the effect of a lattice of antidots on spin relaxation in twodimensional electron systems. The spin relaxation time is calculated as a function of geometrical parameters describing the antidot lattice, namely, the antidot radius and the distance between their centers. It is shown that spin polarization relaxation can be efficiently suppressed by the chaotic spatial motion due to the antidot lattice. This phenomenon offers a new approach to spin coherence manipulation in spintronics devices.Comment: submitted to Phys. Rev.

Compact Source of Electron Beam for Facility of Electron-Beam Welding with the Location of the Electron Gun and the Source of High Voltage in a Single Monoblock. Concept and Bench Tests of the Monoblok Prototype

Представлен прототип компактного источника электронного пучка для установок электронно-лучевой сварки с расположением электронной пушки и источника высоковольтного напряжения в едином моноблоке. Размещение электронной пушки, источника высоковольтного напряжения, электроники управления пучком и питания накала катода источника электронного пучка для электронно-лучевой сварки в едином корпусе-моноблоке снижает вес и стоимость (за счёт уменьшения количества используемых материалов), объём и занимаемые производственные площади. Это существенно расширяет возможности применения представляемого типа источников электронного пучка в разнообразных областях деятельности человека, в том числе в космических технологиях в открытом пространстве космоса. Цель работы – показать целесообразность концепции компоновки источника электронного пучка в едином корпусе-моноблоке на примере стендовых испытаний прототипа источника-моноблока. Спроектирован и изготовлен прототип источника-моноблока. Проведены его предварительные стендовые испытания с лазерным подогревом катода. Обсуждаются возможные применения. Получен электронный ток источника до 70 мА с энергией 90 кэВ. Данный результат демонстрирует возможность практической реализации нового способа компоновки источника электронного пучкаA prototype of an electron beam compact source for electron-beam welding is presented. The electron gun and a high-voltage source are united in a single monoblock. The placement of the electron gun, the high-voltage source, the beam control electronics and the power supply of the cathode heating of the electron beam source for electron beam welding in a single monoblock housing reduces weight and cost by reducing the amount of materials used, volume and occupied production areas. This significantly expands the possibilities of using the presented type of electron beam sources in various fields of human activity, including space technologies in the open space of space. The purpose of the work is to show the expediency of the concept of arranging the electron beam source in the single monoblock housing as the example of bench tests of the source prototype. The prototype of the monoblock was designed and manufactured. Its preliminary bench tests with laser cathode heating were carried out. Its possible applications are discussed. An electron source current up to 70 mA with an energy of 90 keV was obtained. The result obtained demonstrates the possibility of practical implementation of a new method of arranging an electron beam sourc

Author Correction: Federated learning enables big data for rare cancer boundary detection.

10.1038/s41467-023-36188-7NATURE COMMUNICATIONS14