Photonic molecules and spectral engineering

This chapter reviews the fundamental optical properties and applications of pho-tonic molecules (PMs) - photonic structures formed by electromagnetic coupling of two or more optical microcavities (photonic atoms). Controllable interaction between light and matter in photonic atoms can be further modified and en-hanced by the manipulation of their mutual coupling. Mechanical and optical tunability of PMs not only adds new functionalities to microcavity-based optical components but also paves the way for their use as testbeds for the exploration of novel physical regimes in atomic physics and quantum optics. Theoretical studies carried on for over a decade yielded novel PM designs that make possible lowering thresholds of semiconductor microlasers, producing directional light emission, achieving optically-induced transparency, and enhancing sensitivity of microcavity-based bio-, stress- and rotation-sensors. Recent advances in material science and nano-fabrication techniques make possible the realization of optimally-tuned PMs for cavity quantum electrodynamic experiments, classical and quantum information processing, and sensing.Comment: A review book chapter: 29 pages, 19 figure

ACETAZOLAMIDE IN PEDIATRIC NEUROLOGY: HISTORY AND PERSPECTIVE OF CILNICAL USE

Resume the up tob date pharmacological and clinical findings have revealed new opportunities for the use of known for a long time pharmaceutical agents in various fields of practical medicine. For more than 50 years acetozolamide, systemic carbonic anhydrase inhibitor, has been used in neurology to correct liquorodynamic disorders. High clinical efficacy and good tolerb ability in longbterm use has made acetazolamide an essential agent in pediatric neurology, along with this the true therapeutic application of acetazolamide is much wider than it was traditionally thought. This review analyzes the experience of administration of the drug in different branches of pediatric neurology, including those where acetazolamide has been traditionally used along with novel applications to administration of the drug in children.Key words: acetozolamide, carboanhydrase, children, sleep apnea syndrome, glaucoma, hydrocephaly, episodic ataxia type II, migraine, intracranial idiopathic benign hemiplegic hypertension

POSSIBILITIES OF COMBINATIONAL MAGNESIAL AND NEUROPROTECTOR THERAPY IN PATIENTS WITH EARLY CEREBROVASCULAR PATHOLOGY

The serum level of magnesium was evaluated in 232 teenagers and adolescents with early cerebrovascular diseases aged 16–21 years. In cases of magnesium deficiency, monotherapy with complex magnesium medication is an effective treatment both for concurrent magnesium deficiency and for early forms of cerebrovascular pathology with different patterns of vascular response (hyper_ and hypoconstrictive variants). Maximum normotensive effect of the therapy and maximal efficacy in treating vertigo and headaches is reached in combinational therapy with vinpocetin and complex magnesium medication. a combination of complex magnesium medication with bylobil potentiates antiasthenic effect, mostly through diminishing excessive neuron muscular irritability and paresthesiae.Key words: teenagers, magnesium, b6 vitamin, cavinton, bylobil, potentiative therapy, early forms of cerebrovascular diseases

Electroluminescence from amorphous crystalline silicon heterostructures

Electroluminescence from Amorphous Crystalline Silicon Heterostructure

Rational strategy for studying microbiome of the ocular surface of people using hard contact lenses by method of 16s rrna gene metabarcoding

© 2020, Media Sphera Publishing Group. All rights reserved. The study is based on the hypothesis that high taxonomic diversity of bacteria detectable on the eye surface by molecular genetic methods is attributed to the high level of its contamination by skin microflora. Such contamination would make it problematic to identify the fractions of real ocular surface microbiome, which remains behind the one-percent cut-off threshold adopted in the metagenomic analysis. Hard contact lenses for long-wearing act as a physical filter preventing DNA contamination from random microorganisms, and at the same time providing adhesion to the living cells of bacteria and fungi. To confirm this assumption, a detailed analysis of references was carried out, supplemented by original laboratory research. Material and methods. The analysis included 16 hard contact lenses obtained from 11 patients with impaired refraction (myopia). Additionally, conjunctival mucosa scrapings were collected from 42 patients. Samples were cross-analyzed by 16S rRNA gene se-quencing using 454 GS Junior (Ion Torrent) and Illumina MiSeq platforms. Results. Results obtained by the Illumina platform (analysis of the V3-V4 variable region of the 16S rRNA gene) showed better con-vergence with the data of culture tests reported in the literature. The major microorganism groups found were: Acinetobacter (39%), Gluconacetobacter (10.8%), Propionibacterium (9.3%), Corynebacterium (9.3%), Staphylococcus (7.2%), Streptococcus (7%), Pseudomonas (4.1%), Micrococcus (3.3%), Yersinia (3%), Chondromyces (2.4%), Serratia (2.3%), and Bacillus (2.1%). Analysis of the samples obtained directly from the mucosa revealed dominance of typical skin-associated microorganisms. Conclusion. The present study proposes a contamination-reduction algorithm for microbiological testing of the ocular surface using hard contact lenses for prolonged wearing as a carrier for microbial DNA

POSSIBILITIES OF COMBINATIONAL MAGNESIAL AND NEUROPROTECTOR THERAPY IN PATIENTS WITH EARLY CEREBROVASCULAR PATHOLOGY

The serum level of magnesium was evaluated in 232 teenagers and adolescents with early cerebrovascular diseases aged 16–21 years. In cases of magnesium deficiency, monotherapy with complex magnesium medication is an effective treatment both for concurrent magnesium deficiency and for early forms of cerebrovascular pathology with different patterns of vascular response (hyper_ and hypoconstrictive variants). Maximum normotensive effect of the therapy and maximal efficacy in treating vertigo and headaches is reached in combinational therapy with vinpocetin and complex magnesium medication. a combination of complex magnesium medication with bylobil potentiates antiasthenic effect, mostly through diminishing excessive neuron muscular irritability and paresthesiae.Key words: teenagers, magnesium, b6 vitamin, cavinton, bylobil, potentiative therapy, early forms of cerebrovascular diseases