The first dozen years of the history of ITEP Theoretical Physics Laboratory

The theoretical investigations at ITEP in the years 1945-1958 are reviewed. There are exposed the most important theoretical results, obtained in the following branches of physics: 1) the theory of nuclear reactors on thermal neutrons; 2) the hydrogen bomb project ("Tube" in USSR and "Classical Super" in USA); 3) radiation theory; ~4) low temperature physics; 5) quantum electrodynamics and quantum field theories; 6) parity violation in weak interactions, the theory of $\beta$-decay and other weak processes; 7) strong interaction and nuclear physics. To the review are added the English translations of few papers, originally published in Russian, but unknown (or almost unknown) to Western readers.Comment: 55 pages, 5 fig

Acoustoelectric pumping through a ballistic point contact in the presence of magnetic fields

The acoustoelectric current, J, induced in a ballistic point contact (PC) by a surface acoustic wave is calculated in the presence of a perpendicular magnetic field, B. It is found that the dependence of the current on the Fermi energy in the terminals is strongly correlated with that of the PC conductance: J is small at the conductance plateaus, and is large at the steps. Like the conductance, the acoustoelectric current has the same functional behavior as in the absence of the field, but with renormalized energy scales, which depend on the strength of the magnetic field, | B|.Comment: 7 page

Is weak temperature dependence of electron dephasing possible?

The first-principle theory of electron dephasing by disorder-induced two state fluctuators is developed. There exist two mechanisms of dephasing. First, dephasing occurs due to direct transitions between the defect levels caused by inelastic electron-defect scattering. The second mechanism is due to violation of the time reversal symmetry caused by time-dependent fluctuations of the scattering potential. These fluctuations originate from an interaction between the dynamic defects and conduction electrons forming a thermal bath. The first contribution to the dephasing rate saturates as temperature decreases. The second contribution does not saturate, although its temperature dependence is rather weak, $\propto T^{1/3}$. The quantitative estimates based on the experimental data show that these mechanisms considered can explain the weak temperature dependence of the dephasing rate in some temperature interval. However, below some temperature dependent on the model of dynamic defects the dephasing rate tends rapidly to zero. The relation to earlier studies of the dephasing caused by the dynamical defects is discussed.Comment: 14 pages, 6 figures, submitted to PR

HypoRiPPAtlas as an Atlas of hypothetical natural products for mass spectrometry database search

Recent analyses of public microbial genomes have found over a million biosynthetic gene clusters, the natural products of the majority of which remain unknown. Additionally, GNPS harbors billions of mass spectra of natural products without known structures and biosynthetic genes. We bridge the gap between large-scale genome mining and mass spectral datasets for natural product discovery by developing HypoRiPPAtlas, an Atlas of hypothetical natural product structures, which is ready-to-use for in silico database search of tandem mass spectra. HypoRiPPAtlas is constructed by mining genomes using seq2ripp, a machine-learning tool for the prediction of ribosomally synthesized and post-translationally modified peptides (RiPPs). In HypoRiPPAtlas, we identify RiPPs in microbes and plants. HypoRiPPAtlas could be extended to other natural product classes in the future by implementing corresponding biosynthetic logic. This study paves the way for large-scale explorations of biosynthetic pathways and chemical structures of microbial and plant RiPP classes