Considering documents in lifelog information retrieval

Lifelogging is a research topic that is receiving increasing attention and although lifelog research has progressed in recent years, the concept of what represents a document in lifelog retrieval has not yet been sufficiently explored. Hence, the generation of multimodal lifelog documents is a fundamental concept that must be addressed. In this paper, I introduce my general perspective on generating documents in lifelogging and reflect on learnings from collecting multimodal lifelog data from a number of participants in a study on lifelog data organization. In addition, the main motivation be- hind document generation is proposed and the challenges faced while collecting data and generating documents are discussed in detail. Finally, a process for organizing the documents in lifelog data retrieval is proposed, which I intend to follow in my PhD research

Quorum sensing modulates colony morphology through alkyl quinolones in Pseudomonas aeruginosa

This is the publisher’s final pdf. The published article is copyrighted by BioMed Central and can be found at: http://www.biomedcentral.com/.Background: Acyl-homoserine lactone (acyl-HSL) and alkyl quinolone (AQ) based quorum-sensing (QS) systems are important for Pseudomonas aeruginosa virulence and biofilm formation. The effect of QS on biofilm formation is influenced by various genetic and environmental factors. Here, we used a colony biofilm assay to study the effect of the central acyl-HSL QS regulator, LasR, on biofilm formation and structure in the representative clinical P. aeruginosa isolate ZK2870. \ud \ud Results: A lasR mutant exhibited wrinkled colony morphology at 37 C in contrast to the smooth colony morphology of the wild-type. Mutational analysis indicated that wrinkling of the lasR mutant is dependent on pel, encoding a biofilm matrix exopolysaccharide. Suppressor mutagenesis and complementation analysis implicated the AQ signaling pathway as the link between las QS and colony morphology. In this pathway, genes pqsA-D are involved in the synthesis of 4-hydroxyalkyl quinolines ("Series A congeners"), which are converted to 3,4-dihydroxyalkyl quinolines ("Series B congeners", including the well-characterized Pseudomonas Quinolone Signal, PQS) by the product of the LasR-dependent pqsH gene. Measurement of AQ in the wild-type, the lasR pqsA::Tn suppressor mutant as well as the defined lasR, pqsH, and lasR pqsH mutants showed a correlation between 4-hydroxyalkyl quinoline levels and the degree of colony wrinkling. Most importantly, the lasR pqsH double mutant displayed wrinkly morphology without producing any 3,4-dihydroxyalkyl quinolines. Constitutive expression of pqsA-D genes in a lasR pqsR:Tnmutant showed that colony wrinkling does not require the AQ receptor PqsR

Exploring Relationship between Software Product Quality Metrics

This research paper aims to explore the relationship between internal and external software quality metrics in order to estimate software quality more accurately. Internal metrics measure the software itself whereas external metrics measure the behavior of the computer based system. Users can select and apply these metrics according to their individual application domain

Episiotomy site endometriosis: a rare case report

Endometriosis is defined as the presence of endometrial tissue apart from its usual location. Scar endometriosis is an infrequent type of extra pelvic endometriosis. Viable decidual endometrial cells are likely to be transplanted in the episiotomy wounds during normal delivery and subsequent growth may occur. We present here a case of 22 year old female with perineal endometriosis at the episiotomy site. The clinical, operative and pathological findings are reported