Cognitive privacy middleware for deep learning mashup in environmental IoT

Data mashup is a Web technology that combines information from multiple sources into a single Web application. Mashup applications support new services, such as environmental monitoring. The different organizations utilize data mashup services to merge data sets from the different Internet of Multimedia Things (IoMT) context-based services in order to leverage the performance of their data analytics. However, mashup, different data sets from multiple sources, is a privacy hazard as it might reveal citizens specific behaviors in different regions. In this paper, we present our efforts to build a cognitive-based middleware for private data mashup (CMPM) to serve a centralized environmental monitoring service. The proposed middleware is equipped with concealment mechanisms to preserve the privacy of the merged data sets from multiple IoMT networks involved in the mashup application. In addition, we presented an IoT-enabled data mashup service, where the multimedia data are collected from the various IoMT platforms, and then fed into an environmental deep learning service in order to detect interesting patterns in hazardous areas. The viable features within each region were extracted using a multiresolution wavelet transform, and then fed into a discriminative classifier to extract various patterns. We also provide a scenario for IoMT-enabled data mashup service and experimentation results

A Framework of New Hybrid Features for Intelligent Detection of Zero Hour Phishing Websites

Existing machine learning based approaches for detecting zero hour phishing websites have moderate accuracy and false alarm rates and rely heavily on limited types of features. Phishers are constantly learning their features and use sophisticated tools to adopt the features in phishing websites to evade detections. Therefore, there is a need for continuous discovery of new, robust and more diverse types of prediction features to improve resilience against detection evasions. This paper proposes a framework for predicting zero hour phishing websites by introducing new hybrid features with high prediction performances. Prediction performance of the features was investigated using eight machine learning algorithms in which Random Forest algorithm performed the best with accuracy and false negative rates of 98.45% and 0.73% respectively. It was found that domain registration information and webpage reputation types of features were strong predictors when compared to other feature types. On individual features, webpage reputation features were highly ranked in terms of feature importance weights. The prediction runtime per webpage measured at 7.63s suggest that our approach has a potential for real time applications. Our framework is able to detect phishing websites hosted in either compromised or dedicated phishing domains

Captive reptile mortality rates in the home and implications for the wildlife trade

The trade in wildlife and keeping of exotic pets is subject to varying levels of national and international regulation and is a topic often attracting controversy. Reptiles are popular exotic pets and comprise a substantial component of the live animal trade. High mortality of traded animals raises welfare concerns, and also has implications for conservation if collection from the wild is required to meet demand. Mortality of reptiles can occur at any stage of the trade chain from collector to consumer. However, there is limited information on mortality rates of reptiles across trade chains, particularly amongst final consumers in the home. We investigated mortality rates of reptiles amongst consumers using a specialised technique for asking sensitive questions, additive Randomised Response Technique (aRRT), as well as direct questioning (DQ). Overall, 3.6% of snakes, chelonians and lizards died within one year of acquisition. Boas and pythons had the lowest reported mortality rates of 1.9% and chameleons had the highest at 28.2%. More than 97% of snakes, 87% of lizards and 69% of chelonians acquired by respondents over five years were reported to be captive bred and results suggest that mortality rates may be lowest for captive bred individuals. Estimates of mortality from aRRT and DQ did not differ significantly which is in line with our findings that respondents did not find questions about reptile mortality to be sensitive. This research suggests that captive reptile mortality in the home is rather low, and identifies those taxa where further effort could be made to reduce mortality rate

A potent nonporphyrin class of photodynamic therapeutic agent: cellular localisation, cytotoxic potential and influence of hypoxia

We have developed a totally new class of nonporphyrin photodynamic therapeutic agents with a specific focus on two lead candidates azadipyrromethene (ADPM)01 and ADPM06. Confocal laser scanning microscopy imaging showed that these compounds are exclusively localised to the cytosolic compartment, with specific accumulation in the endoplasmic reticulum and to a lesser extent in the mitochondria. Light-induced toxicity assays, carried out over a broad range of human tumour cell lines, displayed EC50 values in the micro-molar range for ADPM01 and nano-molar range for ADPM06, with no discernable activity bias for a specific cell type. Strikingly, the more active agent, ADPM06, even retained significant activity under hypoxic conditions. Both photosensitisers showed low to nondeterminable dark toxicity. Flow cytometric analysis revealed that ADPM01 and ADPM06 were highly effective at inducing apoptosis as a mode of cell death. The photophysical and biological characteristics of these PDT agents suggest that they have potential for the development of new anticancer therapeutics

Multi-center feasibility study evaluating recruitment, variability in risk factors and biomarkers for a diet and cancer cohort in India

<p>Abstract</p> <p>Background</p> <p>India's population exhibits diverse dietary habits and chronic disease patterns. Nutritional epidemiologic studies in India are primarily of cross-sectional or case-control design and subject to biases, including differential recall of past diet. The aim of this feasibility study was to evaluate whether a diet-focused cohort study of cancer could be established in India, providing insight into potentially unique diet and lifestyle exposures.</p> <p>Methods</p> <p>Field staff contacted 7,064 households within three regions of India (New Delhi, Mumbai, and Trivandrum) and found 4,671 eligible adults aged 35-69 years. Participants completed interviewer-administered questionnaires (demographic, diet history, physical activity, medical/reproductive history, tobacco/alcohol use, and occupational history), and staff collected biological samples (blood, urine, and toenail clippings), anthropometric measurements (weight, standing and sitting height; waist, hip, and thigh circumference; triceps, sub-scapula and supra-patella skin fold), and blood pressure measurements.</p> <p>Results</p> <p>Eighty-eight percent of eligible subjects completed all questionnaires and 67% provided biological samples. Unique protein sources by region were fish in Trivandrum, dairy in New Delhi, and pulses (legumes) in Mumbai. Consumption of meat, alcohol, fast food, and soft drinks was scarce in all three regions. A large percentage of the participants were centrally obese and had elevated blood glucose levels. New Delhi participants were also the least physically active and had elevated lipids levels, suggesting a high prevalence of metabolic syndrome.</p> <p>Conclusions</p> <p>A high percentage of participants complied with study procedures including biological sample collection. Epidemiologic expertise and sufficient infrastructure exists at these three sites in India to successfully carry out a modest sized population-based study; however, we identified some potential problems in conducting a cohort study, such as limited number of facilities to handle biological samples.</p