Research Advance on the Relationship between Wee1 and Tumor Genesis and Progression

In the process of biological genetic information transmission, complete and correct genetic information can make cell mitosis proceed normally.In the development of most tumor cells, G2/M cell cycle checkpoint becomes the key checkpoint in the process of mitosis due to the lack of G1/S cell cycle checkpoint, which mainly depends on the abnormal DNA information blocked by Wee1 protein kinase in G2 phase to enter M phase and prolong the time of G2 phase to complete DNA sequencing So that the normal genetic information can be passed on. Wee1 protein kinase expression is significantly increased in most tumor cells,making it a potential target for tumor therapy

Negative exponential behavior of image mutual information for pseudo-thermal light ghost imaging: Observation, modeling, and verification

When use the image mutual information to assess the quality of reconstructed image in pseudo-thermal light ghost imaging, a negative exponential behavior with respect to the measurement number is observed. Based on information theory and a few simple and verifiable assumptions, semi-quantitative model of image mutual information under varying measurement numbers is established. It is the Gaussian characteristics of the bucket detector output probability distribution that leads to this negative exponential behavior. Designed experiments verify the model.Comment: 13 pages, 6 figure

Binary sampling ghost imaging: add random noise to fight quantization caused image quality decline

When the sampling data of ghost imaging is recorded with less bits, i.e., experiencing quantization, decline of image quality is observed. The less bits used, the worse image one gets. Dithering, which adds suitable random noise to the raw data before quantization, is proved to be capable of compensating image quality decline effectively, even for the extreme binary sampling case. A brief explanation and parameter optimization of dithering are given.Comment: 8 pages, 7 figure

Abound Hepatic Mitosis: Unusual Morphology in the Intrahepatic Cholelithiasis Patient

To explore the clinicopathological features of abound mitosis of the hepatocytes in intrahepatic cholelithiasis. The clinicopathological data of one case diagnosed as intrahepatic cholelithiasis was collected from Yantai Yuhuangding Hospital and the clinicopathological characters were discussed. A 68-year-old man suffered from the pain in the right upper quadrant and radiology showed multiple stones in the gallbladder and left liver. The images suggested intrahepatic cholelithiasis. The patient received gallbladder and partial hepatectomy. A large number of mitosis was observed and twelve nuclear fissions were found under high magnification, even in some area pathological nuclear fission could be observed in morphology. On the basis of detection in laboratory, the diagnosis of intrahepatic cholelithiasis was made. The patient did not receive any therapy after surgery. The patient was in a good condition after 18 months follow-up. Increased number of hepatic mitosis might be due to the stimulation from stones, hepatic biliary or secondary inflammatory. High index of proliferation should be prevented from the potential misdiagnosis of hepatic tumor