1,908 research outputs found
SURGE: Continuous Detection of Bursty Regions Over a Stream of Spatial Objects
With the proliferation of mobile devices and location-based services,
continuous generation of massive volume of streaming spatial objects (i.e.,
geo-tagged data) opens up new opportunities to address real-world problems by
analyzing them. In this paper, we present a novel continuous bursty region
detection problem that aims to continuously detect a bursty region of a given
size in a specified geographical area from a stream of spatial objects.
Specifically, a bursty region shows maximum spike in the number of spatial
objects in a given time window. The problem is useful in addressing several
real-world challenges such as surge pricing problem in online transportation
and disease outbreak detection. To solve the problem, we propose an exact
solution and two approximate solutions, and the approximation ratio is
in terms of the burst score, where is a parameter
to control the burst score. We further extend these solutions to support
detection of top- bursty regions. Extensive experiments with real-world data
are conducted to demonstrate the efficiency and effectiveness of our solutions
How do China’s lockdown and post-COVID-19 stimuli impact carbon emissions and economic output? Retrospective estimates and prospective trajectories
This paper develops a multi-sector and multi-factor structural gravity model that allows an analytical and quantitative decomposition of the emission and output changes into composition and technique effects. We find that the negative production shock of China's containment policy propagates globally via supply chains, with the carbon-intensive sectors experiencing the greatest carbon emission shocks. We further reveal that China's current stimulus package in 2021-2025 is consistent with China's emission intensity-reduction goals for 2025, but further efforts are required to meet China's carbon emissions-peaking target in 2030 and Cancun 2°C goal. Short-term changes in carbon emissions resulting from lockdowns and initial fiscal stimuli in "economic rescue" period have minor long-term effects, whereas the transitional direction of future fiscal stimulus exerts more predominant impact on long-term carbon emissions. The efficiency improvement effects are more important than the sectoral structure effects of the fiscal stimulus in achieving greener economic growth. [Abstract copyright: © 2022 The Author(s).
Self-assembled mPEG–PCL-g–PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro
Mechanical behaviours and mass transport properties of bone-mimicking scaffolds consisted of gyroid structures manufactured using selective laser melting
Bone scaffolds created in porous structures manufactured using selective laser melting (SLM) are widely used in tissue engineering, since the elastic moduli of the scaffolds are easily adjusted according to the moduli of the tissues, and the large surfaces the scaffolds provide are beneficial to cell growth. SLM-built gyroid structures composed of 316L stainless steel have demonstrated superior properties such as good corrosion resistance, strong biocompatibility, self-supported performance, and excellent mechanical properties. In this study, gyroid structures of different volume fraction were modelled and manufactured using SLM; the mechanical properties of the structures were then investigated under quasi-static compression loads. The elastic moduli and yield stresses of the structures were calculated from stress-strain diagrams, which were developed by conducting quasi-static compression tests. In order to estimate the discrepancies between the designed and as-produced gyroid structures, optical microscopy and micro-CT scanner were used to observe the structures’ micromorphology. Since good fluidness is conducive to the transport of nutrients, computational fluid dynamics (CFD) values were used to investigate the pressure and flow velocity of the channel of the three kinds of gyroid structures. The results show that the sizes of the as-produced structures were larger than their computer aided design (CAD) sizes, but the manufacturing errors are within a relatively stable range. The elastic moduli and yield stresses of the structures improved as their volume fractions increased. Gyroid structure can match the mechanical properties of human bone by changing the porosity of scaffold. The process of compression failure showed that 316L gyroid structures manufactured using SLM demonstrated high degrees of toughness. The results obtained from CFD simulation showed that gyroid structures have good fluidity, which has an accelerated effect on the fluid in the middle of the channel, and it is suitable for transport nutrients. Therefore, we could predict the scaffold's permeability by conducting CFD simulation to ensure an appropriate permeability before the scaffold being manufactured. SLM-built gyroid structures that composed of 316L stainless steel were suitable to be designed as bone scaffolds in terms of mechanical properties and mass-transport properties, and had significant promise
Preparation of poly(ethylene glycol)/polylactide hybrid fibrous scaffolds for bone tissue engineering
Polylactide (PLA) electrospun fibers have been reported as a scaffold for bone tissue engineering application, however, the great hydrophobicity limits its broad application. In this study, the hybrid amphiphilic poly(ethylene glycol) (PEG)/hydrophobic PLA fibrous scaffolds exhibited improved morphology with regular and continuous fibers compared to corresponding blank PLA fiber mats. The prepared PEG/PLA fibrous scaffolds favored mesenchymal stem cell (MSC) attachment and proliferation by providing an interconnected porous extracellular environment. Meanwhile, MSCs can penetrate into the fibrous scaffold through the interstitial pores and integrate well with the surrounding fibers, which is very important for favorable application in tissue engineering. More importantly, the electrospun hybrid PEG/PLA fibrous scaffolds can enhance MSCs to differentiate into bone-associated cells by comprehensively evaluating the representative markers of the osteogenic procedure with messenger ribonucleic acid quantitation and protein analysis. MSCs on the PEG/PLA fibrous scaffolds presented better differentiation potential with higher messenger ribonucleic acid expression of the earliest osteogenic marker Cbfa-1 and mid-stage osteogenic marker Col I. The significantly higher alkaline phosphatase activity of the PEG/PLA fibrous scaffolds indicated that these can enhance the differentiation of MSCs into osteoblast-like cells. Furthermore, the higher messenger ribonucleic acid level of the late osteogenic differentiation markers OCN (osteocalcin) and OPN (osteopontin), accompanied by the positive Alizarin red S staining, showed better maturation of osteogenic induction on the PEG/PLA fibrous scaffolds at the mineralization stage of differentiation. After transplantation into the thigh muscle pouches of rats, and evaluating the inflammatory cells surrounding the scaffolds and the physiological characteristics of the surrounding tissues, the PEG/PLA scaffolds presented good biocompatibility. Based on the good cellular response and excellent osteogenic potential in vitro, as well as the biocompatibility with the surrounding tissues in vivo, the electrospun PEG/PLA fibrous scaffolds could be one of the most promising candidates in bone tissue engineering
Mechanical and Failure Criteria of Air-Entrained Concrete under Triaxial Compression Load after Rapid Freeze-Thaw Cycles
The experiment study on the air-entrained concrete of 100 mm cubes under triaxial compression with different intermediate stress ratio α2=σ2D : σ3D was carried out using a hydraulic-servo testing system. The influence of rapid freeze-thaw cycles and intermediate stress ratio on the triaxial compressive strength σ3D was analyzed according to the experimental results, respectively. The experimental results of air-entrained concrete obtained from the study in this paper and the triaxial compression experimental results of plain concrete got through the same triaxial-testing-system were compared and analyzed. The conclusion was that the triaxial compressive strength is greater than the biaxial and uniaxial compressive strength after the same rapid freeze-thaw cycles, and the increased percentage of triaxial compressive strength over biaxial compressive strength or uniaxial compressive strength is dependent on the middle stress. The experimental data is useful for precise analysis of concrete member or concrete structure under the action complex stress state
UDTIRI: An Open-Source Road Pothole Detection Benchmark Suite
It is seen that there is enormous potential to leverage powerful deep
learning methods in the emerging field of urban digital twins. It is
particularly in the area of intelligent road inspection where there is
currently limited research and data available. To facilitate progress in this
field, we have developed a well-labeled road pothole dataset named Urban
Digital Twins Intelligent Road Inspection (UDTIRI) dataset. We hope this
dataset will enable the use of powerful deep learning methods in urban road
inspection, providing algorithms with a more comprehensive understanding of the
scene and maximizing their potential. Our dataset comprises 1000 images of
potholes, captured in various scenarios with different lighting and humidity
conditions. Our intention is to employ this dataset for object detection,
semantic segmentation, and instance segmentation tasks. Our team has devoted
significant effort to conducting a detailed statistical analysis, and
benchmarking a selection of representative algorithms from recent years. We
also provide a multi-task platform for researchers to fully exploit the
performance of various algorithms with the support of UDTIRI dataset.Comment: Database webpage: https://www.udtiri.com/, Kaggle webpage:
https://www.kaggle.com/datasets/jiahangli617/udtir
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