Progress on genetic polymorphism associated with diabetic retinopathy

Diabetic retinopathy(DR)is one of the most serious complications of diabetes, as the second general blindness disease in the world currently. The development of procedures for prevention and treatment of DR is one of the most important problems that should be solved currently. A lot of researches show that the development of DR is determined by genetics. The current research advance in DR relevant gene is reviewed in this article

Research and progress of front-end readout prototype system for GRANDProto300

GRANDProto300 is the planned 300-antenna pathfinder array of the Giant Radio Array for Neutrino Detection (GRAND), of which the first 100 detection units have been already produced. Its main goal is to demonstrate the viability of the detection of the radio emission from air showers initiated by inclined ultra-high-energy cosmic rays with energies of $10^{16.5}$ to $10^{18.5}$ eV, covering the purported transition region from their Galactic to extragalactic origin. The front-end readout system of each detection unit of GRANDProto300 processes signals from the radio antenna and the particle detector, generates the first-level trigger, and communicates with a central processing station. Based on earlier designs, we have built the first prototype of this system using two development boards and one self-designed front-end board. We present our new design that is improved and more economical than the earlier one, as well as test results and prospects for future work.Comment: Presented at the 38th International Cosmic Ray Conference (ICRC 2023

DAQE: Enhancing the Quality of Compressed Images by Finding the Secret of Defocus

Image defocus is inherent in the physics of image formation caused by the optical aberration of lenses, providing plentiful information on image quality. Unfortunately, the existing quality enhancement approaches for compressed images neglect the inherent characteristic of defocus, resulting in inferior performance. This paper finds that in compressed images, the significantly defocused regions are with better compression quality and two regions with different defocus values possess diverse texture patterns. These findings motivate our defocus-aware quality enhancement (DAQE) approach. Specifically, we propose a novel dynamic region-based deep learning architecture of the DAQE approach, which considers the region-wise defocus difference of compressed images in two aspects. (1) The DAQE approach employs fewer computational resources to enhance the quality of significantly defocused regions, while more resources on enhancing the quality of other regions; (2) The DAQE approach learns to separately enhance diverse texture patterns for the regions with different defocus values, such that texture-wise one-on-one enhancement can be achieved. Extensive experiments validate the superiority of our DAQE approach in terms of quality enhancement and resource-saving, compared with other state-of-the-art approaches

Optical Monitoring of the Seyfert Galaxy NGC 4151 and Possible Periodicities in the Historical Light Curve

We report B, V, and R band CCD photometry of the Seyfert galaxy NGC 4151 obtained with the 1.0-m telescope at Weihai Observatory of Shandong University and the 1.56-m telescope at Shanghai Astronomical Observatory from 2005 December to 2013 February. Combining all available data from literature, we have constructed a historical light curve from 1910 to 2013 to study the periodicity of the source using three different methods (the Jurkevich method, the Lomb-Scargle periodogram method and the Discrete Correlation Function method). We find possible periods of P_1=4\pm0.1, P_2=7.5\pm0.3 and P_3=15.9\pm0.3 yr.Comment: 8 pages, 5 figures, Accepted by Research in Astronomy and Astrophysic

Application of different colorants in the surgery of idiopathic macular hole

Internal limiting membrane(ILM)peeling is commonly used in the operation of idiopathic macular hole(IMH)surgery. The success of ILM peeling has been greatly improved with the assistance of vital dyes. Currently, several kinds of vital dyes such as indocyanine green(ICG), brilliant blue G(BBG)are applied in the ILM staining. However, all of the vital dyes have potential toxicity and side effects on the retina. In recent years, many kinds of dyes and staining improved emerge in endlessly. This paper reports the progress in the application of different colorants in the operation of IMH