Blow up solutions to a viscoelastic fluid system and a coupled Navier-Stokes/Phase-Field system in R^2

We find explicit solutions to both the Oldroyd-B model with infinite Weissenberg number and the coupled Navier-Stokes/Phase-Field system. The solutions blow up in finite time.Comment: 5 page

Theory Research on Evolution and Protection of River Ecosystem under the Influence of Human Activities

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchive

Effects of Climate Warming on Net Primary Productivity in China During 1961–2010

The response of ecosystems to different magnitudes of climate warming and corresponding precipitation changes during the last few decades may provide an important reference for predicting the magnitude and trajectory of net primary productivity (NPP) in the future. In this study, a process-based ecosystem model, Carbon Exchange between Vegetation, Soil and Atmosphere (CEVSA), was used to investigate the response of NPP to warming at both national and subregional scales during 1961–2010. The results suggest that a 1.3°C increase in temperature stimulated the positive changing trend in NPP at national scale during the past 50 years. Regardless of the magnitude of temperature increase, warming enhanced the increase in NPP; however, the positive trend of NPP decreased when warming exceeded 2°C. The largest increase in NPP was found in regions where temperature increased by 1–2°C, and this rate of increase also contributed the most to the total increase in NPP in China\u27s terrestrial ecosystems. Decreasing precipitation depressed the positive trend in NPP that was stimulated by warming. In northern China, warming depressed the increasing trend of NPP and warming that was accompanied by decreasing precipitation led to negative changing trends in NPP in large parts of northern China, especially when warming exceeded 2°C. However, warming stimulated the increase in NPP until warming was greater than 2°C, and decreased precipitation helped to increase the NPP in southern China

A Static Voltage Security Region for Centralized Wind Power Integration-Part II: Applications

In Part I of this work, a static voltage security region was introduced to guarantee the safety of wind farm reactive power outputs under both base conditions and N-1 contingency. In this paper, a mathematical representation of the approximate N-1 security region has further studied to provide better coordination among wind farms and help prevent cascading tripping following a single wind farm trip. Besides, the influence of active power on the security region is studied. The proposed methods are demonstrated for N-1 contingency cases in a nine-bus system. The simulations verify that the N-1 security region is a small subset of the security region under base conditions. They also illustrate the fact that if the system is simply operated below the reactive power limits, without coordination among the wind farms, the static voltage is likely to exceed its limit. A two-step optimal adjustment strategy is introduced to shift insecure operating points into the security region under N-1 contingency. Through extensive numerical studies, the effectiveness of the proposed technique is confirmed

RhoA/ROCK-dependent moesin phosphorylation regulates AGE-induced endothelial cellular response

<p>Abstract</p> <p>Background</p> <p>The role of advanced glycation end products (AGEs) in the development of diabetes, especially diabetic complications, has been emphasized in many reports. Accumulation of AGEs in the vasculature triggers a series of morphological and functional changes in endothelial cells (ECs) and induces an increase of endothelial permeability. This study was to investigate the involvement of RhoA/ROCK-dependent moesin phosphorylation in endothelial abnormalities induced by AGEs.</p> <p>Methods</p> <p>Using human dermal microvascular endothelial cells (HMVECs), the effects of human serum albumin modified-AGEs (AGE-HSA) on the endothelium were assessed by measuring monolayer permeability and staining of F-actin in HMVECs. Activations of RhoA and ROCK were determined by a luminescence-based assay and immunoblotting. Transfection of recombinant adenovirus that was dominant negative for RhoA (RhoA N19) was done to down-regulate RhoA expression, while adenovirus with constitutively activated RhoA (RhoA L63) was transfected to cause overexpression of RhoA in HMVECs. H-1152 was employed to specifically block activation of ROCK. Co-immunoprecipitation was used to further confirm the interaction of ROCK and its downstream target moesin. To identify AGE/ROCK-induced phosphorylation site in moesin, two mutants pcDNA3/HA-moesinT^558Aand pcDNA3/HA-moesinT^558Dwere applied in endothelial cells.</p> <p>Results</p> <p>The results showed that AGE-HSA increased the permeability of HMVEC monolayer and triggered the formation of F-actin-positive stress fibers. AGE-HSA enhanced RhoA activity as well as phosphorylation of ROCK in a time- and dose-dependent manner. Down-regulation of RhoA expression with RhoA N19 transfection abolished these AGE-induced changes, while transfection of RhoA L63 reproduced the AGE-evoked changes. H-1152 attenuated the AGE-induced alteration in monolayer permeability and cytoskeleton. The results also confirmed the AGE-induced direct interaction of ROCK and moesin. Thr558 was further identified as the phosphorylating site of moesin in AGE-evoked endothelial responses.</p> <p>Conclusion</p> <p>These results confirm the involvement of RhoA/ROCK pathway and subsequent moesin Thr558 phosphorylation in AGE-mediated endothelial dysfunction.</p