Theoretical Justification of the Dermatoglyphics Use As Basic Identification Method

The article analyzes the main literature sources providing a holistic view of the state and issues of studying the issue related to the possibility of using the dermatoglyphic research method for identification purpose; it is about external recognition, behavioral, psychological identification. The main directions of application of the dermatoglyphic method, providing the study of this issue, are highlighted. Problematic issues related to the areas of application of the dermatoglyphic method have been studied and further prospects for its study have been outlined

Features of sonographic parameters of liver in practically healthy men of different somatotypes, in the Podilski region of Ukraine

The analysis of liver sonographic parameters of healthy men of the Podilski region of Ukraine who are of different somatotypes has revealed significant differences only in the thickness of the right lobe of the liver on inhalation, as well as in the width of the caudate lobe of the liver and the densitometry of the left lobe of the liver parenchyma on exhalation and during inhalation. No significant differences or trends between healthy men of different somatotypes were seen in the rest of the sonographic parameters of liver (oblique vertical size of the right lobe of the liver on exhalation and on inhalation, the thickness of the right lobe of the liver on exhalation, the cranio-caudal size of the left lobe of the liver on exhalation and inhalation, the thickness of the left lobe of the liver on exhalation and in inhalation, as well as the length of the caudate particle of the liver and densitometry of right lobe of liver parenchyma on exhalation and inhalation)

Cytokines and their regulators in rat lung following scorpion envenomation

Nowadays, more than two billion inhabitants of underdeveloped tropical and subtropical countries are at risk of being stung by scorpions. Scorpion stings annually cause 2000–3000 deaths as they can lead to the respiratory and/or cardiovascular complications. Pathogenesis of lung damage under scorpion envenomation is often comprehensive. Respiratory failure can have a cardiogenic origin, associated with venom neurotoxin action. However, some venom components can stimulate pro-inflammatory signaling cascades followed by cytokines synthesis, recruit and activate immune cells, participating in the inflammatory response in lung injury. Scorpions of the Leiurus genus (''deathstalker'') are one of the most dangerous Arthropoda. To date, 22 species of this genus have been described, but the venom composition and the mechanisms of tissues damage under envenomation have been studied to some extent only for L. quinquestriatus, L. hebraeus, and L. abdullahbayrami. Scorpions of L. macroctenus species are expected to be very hazardous, but the possibility of their venom cause inflammation in the lung tissue has not been investigated to date. Therefore, in this study, we focused on evaluating the levels of cytokines and their regulators – transcription factors (HIF-1α and NF-κB) and growth factors (FGF-2, VEGF, and EGF) – in rat lung homogenates after L. macroctenus envenomation. The results revealed a decrease in the levels of most pro-inflammatory cytokines (IL-6, IL-8, IL-1β and TNF-α) with simultaneous rise in the content of both anti-inflammatory cytokines (IL-4 and IL-10) and interferon-γ. Furthermore, the levels of all researched transcription factors and growth factors were shown to be increased too. The detected changes peak occurred at 24 h, whereas a tendency towards all indicators values normalization was observed in 72 h after venom injection. Thus, our results did not reveal signs of a classic inflammatory process in the lungs of rats injected with L. macroctenus venom. However, the obtained data indicate venom influence both on cytokine profile and on their regulators content in the rat lungs, which is a feature of certain alterations in the innate immune response, caused by studied venom components. But, the mechanisms of the changes we found require additional researches