4,920 research outputs found

    Modified Gravity Away from a Λ\LambdaCDM Background

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    Within the effective field theory approach to cosmic acceleration, the background expansion can be specified separately from the gravitational modifications. We explore the impact of modified gravity in a background different from a cosmological constant plus cold dark matter (Λ\LambdaCDM) on the stability and cosmological observables, including covariance between gravity and expansion parameters. In No Slip Gravity the more general background allows more gravitational freedom, including both positive and negative Planck mass running. We examine the effects on cosmic structure growth, as well as showing that a viable positive integrated Sachs-Wolfe effect crosscorrelation easily arises from this modified gravity theory. Using current data we constrain parameters with a Monte Carlo analysis, finding a maximum running αM0.03|\alpha_M|\lesssim 0.03. We provide the modified {\tt hi\_class} code publicly on GitHub, now enabling computation and inclusion of the redshift space distortion observable fσ8f\sigma_8 as well as the No Slip Gravity modifications.Comment: 14 pages, 13 figures. Matches published version in JCAP, LCDM discussion adde

    Microcavity supported lipid membranes: versatile platforms for building asymmetric lipid bilayers and for protein recognition

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    Microcavity supported lipid bilayers (MSLB) are contact-free membranes suspended across aqueousfilled pores that maintain the lipid bilayer in a highly fluidic state and free from frictional interactions with substrate. Such platforms offer the prospect of liposome-like fluidity with the compositional versatility and addressability of supported lipid bilayers and thus offer significant opportunity for modelling membrane asymmetry, protein-membrane interactions and aggregation at the membrane interface. Herein, we evaluate their performance by studying the effect of transmembrane lipid asymmetry on lipid diffusivity, membrane viscosity and cholera toxin- ganglioside recognition across six symmetric and asymmetric membranes including binary compositions containing both fluid and gel phase, and ternary phase separated membrane compositions. Fluorescence lifetime correlation spectroscopy (FLCS) was used to determine the lateral mobility of lipid and protein, and electrochemical impedance spectroscopy (EIS) enabled detection of protein-membrane assembly over the nanomolar range. Transmembrane leaflet asymmetry was observed to have profound impact on membrane electrochemical resistance where the resistance of a ternary symmetric phase separated bilayer was found to be at least 2.6 times higher than the asymmetric bilayer with analogous composition at the distal leaflet but where the lower leaflet comprised only 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC). Similarly, the diffusion coefficient for MSLBs was observed to be 2.5 fold faster for asymmetric MSLBs where the lower leaflet is DOPC alone. Our results demonstrate that interplay of lipid packing across both membrane leaflets and concentration of GM1 both affect the extent of cholera toxin aggregation and consequent diffusion of the cholera-GM1 aggregates. Given that true biomembranes are both fluidic and asymmetric, MSLBs offer the opportunity for building greater biomimicry into biophysical models and the approach described demonstrates the value of MSLBs in studying aggregation and membrane associated multivalent interactions prevalent in many carbohydrates mediated processes

    Improved decision for a resource-efficient fusion scheme in cooperative spectrum sensing

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    Paper presented at at 2015 International Workshop on Telecommunications (IWT), 14th to 17th of June, Santa Rita do Sapucai, Brazil. Abstract Recently, a novel decision fusion scheme for cooperative spectrum sensing was proposed, aiming at saving resources in the reporting channel transmissions. Secondary users are allowed to report their local decisions through the symbols of binary modulations, at the same time and with the same carrier frequencies. As a consequence, the transmitted symbols add incoherently at the fusion center, forming a larger set of symbols in which a subset is associated to the presence of the primary signal, and another subset is associated to the absence of such a signal. A Bayesian decision criterion with uniform prior was applied for discriminating these subsets. In this paper we propose a modified decision rule in which the target probabilities of detection and false alarm are taken into account to produce a large performance improvement over the original decision criterion. This improvement comes with practically no cost in complexity and does not demand the knowledge of any additional information when compared to the original rule

    Stable isotopic analysis of atmospheric methane by infrared spectroscopy by use of diode laser difference-frequency generation

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    An infrared absorption spectrometer has been constructed to measure the stable isotopic composition of atmospheric methane samples. The spectrometer employs periodically poled lithium niobate to generate 15 μW of tunable difference-frequency radiation from two near-infrared diode lasers that probe the ν3 rotational-vibrational band of methane at 3.4 μm. To enhance the signal, methane is extracted from 25 l of air by use of a cryogenic chromatographic column and is expanded into the multipass cell for analysis. A measurement precision of 12‰ is demonstrated for both δ13C and δD
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