Nasolabial cyst: imaging findings

Nasolabial cysts are rare nonodontogenic lesions of the maxillofacial area. Other odontogenic and non-odontogenic masses should be taken into consideration in definitive diagnosis. In this case report, ultrasonography, computed tomography and magnetic resonance imaging findings of a nasolabial cyst in a 32-year-old male patient were presented with the literature. [Cukurova Med J 2016; 41(1.000): 183-186

Effect of mazEF, higBA and relBE toxin-antitoxin systems on antibiotic resistance in Pseudomonas aeruginosa and Staphylococcus isolates

SANDALLI, Cemal/0000-0002-1298-3687WOS: 000455275200003PubMed: 30627331Background A toxin-antitoxin (TA) system is a set of two or more closely linked genes that are encoded as a poison and a corresponding antidote on a protein. in typical bacterial physiology, an antitoxin binds to a toxin and neutralizes it, which prevents the bacterium from killing itself. We aimed to determine whether P.aeruginosa and Staphylococcus isolates have TA genes and to investigate whether there is a relationship between the expression levels of TA genes and resistance to antibiotics. Methods This study included 92 P. aeruginosa and 148 Staphylococcus isolates. RelBE, higBA genes were investigated in P.aeruginosa by multiplex polyrnerase chain reaction (PCR). the mazEF gene and the all TA genes expression were detected by real time PCR. Results RelBE and higBA genes were detected in 100% of P. aeruginosa. It was found that the level of relBE TA gene expression is increased in isolates sensitive to aztreonam compared to resistant isolates (p0.05) whereas there was a significant difference between MSSA and coagulase-negative Stap,Vomccar (CNS) isolates, MRSA and CNS isolates (p<0.05). the levels of mazEF gene expression were found to be higher in isolates sensitive to gentamicin, ciprofloxacin, levofloxacin, clindamycin, phosphomycine, nitrofurantoin, fusidic acid, cefoxitin compared to resistant isolates (p<0.05). Conclusion Studies on the prevalence and functionality of TA systems emphasize that it may be possible to have new sensitive regions in bacteria by activating TA systems. the results of this study lead to the idea that resistance to antibiotics can be reduced by increasing TA gene expression levels. But there is need for further studies to support and develop this issue.Gaziosmanpasa UniversityGaziosmanpasa University [BAP-2015/25]This work was supported by Gaziosmanpasa University Research Fund Grants (BAP-2015/25)