Probing GeV-scale MSSM neutralino dark matter in collider and direct detection experiments

Given the recent constraints from the dark matter (DM) direct detections, we examine a light GeV-scale (2-30 GeV) neutralino DM in the alignment limit of the Minimal Supersymmetric Standard Model (MSSM). In this limit without decoupling, the heavy CP-even scalar $H$ plays the role of the Standard Model (SM) Higgs boson while the other scalar $h$ can be rather light so that the DM can annihilate through the $h$ resonance or into a pair of $h$ to achieve the observed relic density. With the current collider and cosmological constraints, we find that such a light neutralino DM above 6 GeV can be excluded by the XENON-1T (2017) limits while the survivied parameter space below 6 GeV can be fully covered by the future germanium-based light dark matter detections (such as CDEX), by the Higgs coupling precison measurements or by the production process $e^+e^- \to hA$ at an electron-positron collider (Higgs factory).Comment: 15 pages, 5 figures. Discussions and references added, version accepted by PL

Simplified TeV leptophilic dark matter in light of DAMPE data

Using a simplified framework, we attempt to explain the recent DAMPE cosmic $e^+ + e^-$ flux excess by leptophilic Dirac fermion dark matter (LDM). The scalar ($\Phi_0$) and vector ($\Phi_1$) mediator fields connecting LDM and Standard Model particles are discussed. Under constraints of DM relic density, gamma-rays, cosmic-rays and Cosmic Microwave Background (CMB), we find that the couplings $P \otimes S$, $P \otimes P$, $V \otimes A$ and $V \otimes V$ can produce the right bump in $e^+ + e^-$ flux for a DM mass around 1.5 TeV with a natural thermal annihilation cross-section $\sim 3 \times 10^{-26} cm^3/s$ today. Among them, $V \otimes V$ coupling is tightly constrained by PandaX-II data (although LDM-nucleus scattering appears at one-loop level) and the surviving samples appear in the resonant region, $m_{\Phi_1} \simeq 2m_{\chi}$. We also study the related collider signatures, such as dilepton production $pp \to \Phi_1 \to \ell^+\ell^-$, and muon $g-2$ anomaly. Finally, we present a possible $U(1)_X$ realization for such leptophilic dark matter.Comment: discussions added, version accepted by JHE

3-Meth­oxy-4-[3-(2-methyl-4-nitro-1H-imidazol-1-yl)prop­oxy]benzaldehyde

In the title mol­ecule, C15H17N3O5, the dihedral angle between the benzene and imidazole rings is 3.69 (2)°. The crystal structure is stabilized by weak inter­molecular C—H⋯O hydrogen bonds and π–π stacking inter­actions with a centroid–centroid distance of 3.614 (1) Å

ACMP: Allen-Cahn Message Passing for Graph Neural Networks with Particle Phase Transition

Neural message passing is a basic feature extraction unit for graph-structured data considering neighboring node features in network propagation from one layer to the next. We model such process by an interacting particle system with attractive and repulsive forces and the Allen-Cahn force arising in the modeling of phase transition. The dynamics of the system is a reaction-diffusion process which can separate particles without blowing up. This induces an Allen-Cahn message passing (ACMP) for graph neural networks where the numerical iteration for the particle system solution constitutes the message passing propagation. ACMP which has a simple implementation with a neural ODE solver can propel the network depth up to one hundred of layers with theoretically proven strictly positive lower bound of the Dirichlet energy. It thus provides a deep model of GNNs circumventing the common GNN problem of oversmoothing. GNNs with ACMP achieve state of the art performance for real-world node classification tasks on both homophilic and heterophilic datasets.Comment: 26 pages, 5 figures. NeurIPS 2022 Workshop on GLFrontiers (Oral). ICLR 2023 (Spotlight

Aquaporin 1, a potential therapeutic target for migraine with aura

The pathophysiology of migraine remains largely unknown. However, evidence regarding the molecules participating in the pathophysiology of migraine has been accumulating. Water channel proteins, known as aquaporins (AQPs), notably AQP-1 and AQP-4, appears to be involved in the pathophysiology of several neurological diseases. This review outlines newly emerging evidence indicating that AQP-1 plays an important role in pain signal transduction and migraine and could therefore serve as a potential therapeutic target for these diseases

A second ortho­rhom­bic polymorph of 2-(pyridin-4-ylmeth­oxy)phenol

The crystal structure of the title compound, C12H11NO2, represents a new ortho­rhom­bic polymorph II of the previously reported ortho­rhom­bic form I [Zhang et al. (2009 ▶) Acta Cryst. E65, o3160]. In polymorph II, the six-membered rings form a dihedral angle of 13.8 (1)° [71.6 (1)° in I], and O—H⋯N hydrogen bonds link mol­ecules into chains along [100], whereas the crystal structure of I features hydrogen-bonded centrosymmetric dimers