12,428 research outputs found
Top-N Recommendation on Graphs
Recommender systems play an increasingly important role in online
applications to help users find what they need or prefer. Collaborative
filtering algorithms that generate predictions by analyzing the user-item
rating matrix perform poorly when the matrix is sparse. To alleviate this
problem, this paper proposes a simple recommendation algorithm that fully
exploits the similarity information among users and items and intrinsic
structural information of the user-item matrix. The proposed method constructs
a new representation which preserves affinity and structure information in the
user-item rating matrix and then performs recommendation task. To capture
proximity information about users and items, two graphs are constructed.
Manifold learning idea is used to constrain the new representation to be smooth
on these graphs, so as to enforce users and item proximities. Our model is
formulated as a convex optimization problem, for which we need to solve the
well-known Sylvester equation only. We carry out extensive empirical
evaluations on six benchmark datasets to show the effectiveness of this
approach.Comment: CIKM 201
Antioxidantactivity In Vitro And Hepatoprotective Effect Of Phlomis Maximowiczii In Vivo
Background: Anumber of medicinal plants and there compounds played a major role in the treatment of hepatic disorders. They were widely used for the treatment of these disorders, and oxidant stress injury was one of the liver injury mechanisms. The present study evaluated the antioxidant activity and the hepatoprotective effect of each extracts of Phlomis maximowiczii.Materials and Methods: The antioxidant activity was assayed by the methods of ABTS, FRAP and DPPH in vitro. Hepatoprotective effect of P. maximowiczii extracts was examined using carbon tetrachloride-induced acute liver injury in mice.Results: P. maximowiczii n-butanol (PMBU) extract, ABTS (IC50=18.96 μg/mL), DPPH (IC50=25.15 μg/mL), and FRAP (RACT50=2775.6±144.18 μmol/g), showed higher scavenging capacity than that of P. maximowiczii ethyl acetate (PMEA). The n-butanol extract could significantly reduce the level of GPT, GOT and MDA (P<0.05, P<0.001 and P<0.001, respectively) and increase the level of SOD (P<0.001), respectively.Conclusion: The antioxidant activity of n-butanol extract in vitro was related with the level ofMDAand SOD in vivo, and hepatoprotective effect of n-butanol extract also had relationship with its antioxidant activity in vivo.Key words: Phlomis maximowiczii, anti-oxidation, acute liver in jury, carbon tetrachloride
An advanced meshless method for time fractional diffusion equation
Recently, because of the new developments in sustainable engineering and renewable energy, which are usually governed by a series of fractional partial differential equations (FPDEs), the numerical modelling and simulation for fractional calculus are attracting more and more attention from researchers. The current dominant numerical method for modeling FPDE is Finite Difference Method (FDM), which is based on a pre-defined grid leading to inherited issues or shortcomings including difficulty in simulation of problems with the complex problem domain and in using irregularly distributed nodes. Because of its distinguished advantages, the meshless method has good potential in simulation of FPDEs. This paper aims to develop an implicit meshless collocation technique for FPDE. The discrete system of FPDEs is obtained by using the meshless shape functions and the meshless collocation formulation. The stability and convergence of this meshless approach are investigated theoretically and numerically. The numerical examples with regular and irregular nodal distributions are used to validate and investigate accuracy and efficiency of the newly developed meshless formulation. It is concluded that the present meshless formulation is very effective for the modeling and simulation of fractional partial differential equations
Interdimensional degeneracies for a quantum three-body system in D dimensions
A new approach is developed to derive the complete spectrum of exact interdimensional degeneracies for a quantum three-body system in D-dimensions. The new method gives a generalization of previous methods
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