Using Creative Writing and Literacy to Dismantle the School to Prison Pipeline

The primary purpose of this research was to elevate the voices of minoritized girls of color (those with intersecting identities such as being Black, Brown and/or gender nonconforming, and/or having a disability) through creative writing and literacy, by engaging them in a process of inquiry that allowed them to creatively express themselves and to share their experiences within the school-to-prison pipeline. Using creative writing and a curriculum that the researcher created, the young women participating in various activities that helped them share their experiences and allowed them to think about countering the narrative about young girls of color and with intersecting identities in alternative education settings. As a result, they presented their findings to educators and administrators; sharing their experiences within the school-to-prison pipeline, as well as the growth shown, and the skills gained that they experienced from participating in the program

Using Creative Writing and Literacy to Dismantle the School to Prison Pipeline

The primary purpose of this research was to elevate the voices of minoritized girls of color (those with intersecting identities such as being Black, Brown and/or gender nonconforming, and/or having a disability) through creative writing and literacy, by engaging them in a process of inquiry that allowed them to creatively express themselves and to share their experiences within the school-to-prison pipeline. Using creative writing and a curriculum that the researcher created, the young women participating in various activities that helped them share their experiences and allowed them to think about countering the narrative about young girls of color and with intersecting identities in alternative education settings. As a result, they presented their findings to educators and administrators; sharing their experiences within the school-to-prison pipeline, as well as the growth shown, and the skills gained that they experienced from participating in the program

The Lethal Effects of Herbicides and Herbicide Residues on the Agriculturally Important Wolf Spider Pardosa milvina

Herbicides are applied to commercial crops with increasing frequency and diversity yet are rarely tested for acute or chronic toxicity effects on beneficial non target species such as spiders We measured the lethal effects of chronic exposure to field relevant doses of herbicide treated soil on an agriculturally abundant wolf spider, Pardosa milvina. We tested six herbicides including atrazine, S-metolachlor, mesotrione, glyphosate, 2,4-D, and dicamba. We also tested a mixture of all six herbicides and a distilled water control. Spiders were housed individually in containers with topsoil previously sprayed with a recommended herbicide dosage or water control group To test for herbicide residue effects, we reared spiders under herbicides exposed to three aging treatments freshly applied herbicides, herbicides aged for 69 days under room temperature laboratory conditions (indoor aged) or aged for 69 days in a greenhouse with variable temperature, humidity, light exposure, and evaporative cycling (outdoor aged) (N=960; n= 40 spiders across 24 treatments) Spiders were maintained on these treated substrates for 48 days and fed crickets (Gryllodes sigillatus). We recorded daily mortality across all spider treatments during the testing period Mesotrione and combined herbicide treated spiders showed very high mortality within two weeks of exposure among both freshly applied and indoor aged soil treatments while mortality was modest across outdoor aged herbicide treatments. Our results indicate that some herbicides are arachnicides but require chronic and prolonged exposure to produce lethal effects. Further, soil bacterial communities alone were insufficient to break down herbicides or reduce their toxicity while photodegradation, bacterial action, temperature variation and evaporation cycles were sufficient to dramatically reduce toxicity during chronic exposure

Assessment of the Angolan (CHERRT) Mobile Laboratory Curriculum for Disaster and Pandemic Response

Introduction: As of April 5, 2020, the World Health Organization reported over one million confirmed cases and more than 62,000 confirmed coronavirus (COVID-19) deaths affecting 204 countries/ regions. The lack of COVID-19 testing capacity threatens the ability of both the United States (US) and low middle income countries (LMIC) to respond to this growing threat, The purpose of this study was to assess the effectiveness through participant self-assessment of a rapid response team (RRT) mobile laboratory curriculumMethods: We conducted a pre and post survey for the purpose of a process improvement assessment in Angola, involving 32 individuals. The survey was performed before and after a 14-day training workshop held in Luanda, Angola, in December 2019. A paired t-test was used to identify any significant change on six 7-point Likert scale questions with α< 0.05 (95% confidence interval).Results: All six of the questions –  1) “I feel confident managing a real laboratory sample test for Ebola or other highly contagious sample;” 2) “I feel safe working in the lab environment during a real scenario;” 3) “I feel as if I can appropriately manage a potentially highly contagious laboratory sample;” 4)“I feel that I can interpret a positive or negative sample during a suspected contagious outbreak;” 5) “I understand basic Biobubble/mobile laboratory concepts and procedures;” and 6) “I understand polymerase chain reaction (PCR) principles” – showed statistical significant change pre and post training. Additionally, the final two questions – “I can more effectively perform my role/position because of the training I received during this course;” and “This training was valuable”  – received high scores on the Likert scale.Conclusion: This Angolan RRT mobile laboratory training curriculum provides the nation of Angola with the confidence to rapidly respond and test at the national level a highly infectious contagion in the region and perform on-scene diagnostics. This mobile RRT laboratory provides a mobile and rapid diagnostic resource when epidemic/pandemic resource allocation may need to be prioritized based on confirmed disease prevalence

Mirror Symmetry for open r-spin invariants

We show that a generating function for open $r$-spin enumerative invariants produces a universal unfolding of the polynomial $x^r$. Further, the coordinates parametrizing this universal unfolding are flat coordinates on the Frobenius manifold associated to the Landau-Ginzburg model $(\mathbb{C},x^r)$ via Saito-Givental theory. This result provides evidence for the same phenomenon to occur in higher dimension, proven in a sequel paper.Comment: 11 page

Development of Remote Monitoring Software For CNC Machines

CNC machines are crucial in precision manufacturing, and monitoring their performance is essential, yet challenging due to the manual effort involved. Addressing this, our project introduces a remote monitoring system for CNC machines that harnesses PLCs, OPC servers, Ignition software, ethernet, and Python. The system enables real-time tracking of machine coordinates, spindle RPM, coolant levels, door status, operating time, real time alarms and overall machine life. It\u27s designed for accessibility from various devices, providing real-time data analysis and improving organizational efficiency without the constant presence of a human operator. The major benefit of our software is that it can be accessed anywhere on any type of device, be it a desktop computer or a cell phone, facilitating valuable real-time analysis of the condition of the machine.https://scholarworks.moreheadstate.edu/celebration_posters_2024/1040/thumbnail.jp

Detecting the Level of Scrap Metal Discard from CNC Machines using Capacitive Sensors

A CNC machine is a machine comprised of a motorized and maneuverable tool and platform that are controlled by a computer according to specific inputs. Our machine are a metal mill (which cuts into metal pieces form the top) and a metal lathe (which cuts into metal pieces from the side). Attached to each of these machines is a waste bin that holds discarded metal and debris from that machines. This bin fills up often and quickly and if it isn\u27t cleared out regularly and cause a build of metal scraps inside the machine and resulting in major malfunctions.https://scholarworks.moreheadstate.edu/celebration_posters_2024/1069/thumbnail.jp

Preferential, enhanced breast cancer cell migration on biomimetic electrospun nanofiber ‘cell highways’

BACKGROUND: Aggressive metastatic breast cancer cells seemingly evade surgical resection and current therapies, leading to colonization in distant organs and tissues and poor patient prognosis. Therefore, high-throughput in vitro tools allowing rapid, accurate, and novel anti-metastatic drug screening are grossly overdue. Conversely, aligned nanofiber constitutes a prominent component of the late-stage breast tumor margin extracellular matrix. This parallel suggests that the use of a synthetic ECM in the form of a nanoscale model could provide a convenient means of testing the migration potentials of cancer cells to achieve a long-term goal of providing clinicians an in vitro platform technology to test the efficacy of novel experimental anti-metastatic compounds. METHODS: Electrospinning produces highly aligned, cell-adhesive nanofiber matrices by applying a strong electric field to a polymer-containing solution. The resulting fibrous microstructure and morphology closely resembles in vivo tumor microenvironments suggesting their use in analysis of migratory potentials of metastatic cancer cells. Additionally, a novel interface with a gel-based delivery system creates CXCL12 chemotactic gradients to enhance CXCR4-expressing cell migration. RESULTS: Cellular dispersions of MCF-10A normal mammary epithelial cells or human breast cancer cells (MCF-7 and MDA-MB-231) seeded on randomly-oriented nanofiber exhibited no significant differences in total or net distance traveled as a result of the underlying topography. Cells traveled ~2-5 fold greater distances on aligned fiber. Highly-sensitive MDA-MB-231 cells displayed an 82% increase in net distance traversed in the presence of a CXCL12 gradient. In contrast, MCF-7 cells exhibited only 31% increase and MCF-10A cells showed no statistical difference versus control or vehicle conditions. MCF-10A cells displayed little sensitivity to CXCL12 gradients, while MCF-7 cells displayed early sensitivity when CXCL12 concentrations were higher. MDA-MB-231 cells displayed low relative expression levels of CXCR4, but high sensitivity resulting in 55-fold increase at late time points due to CXCL12 gradient dissipation. CONCLUSIONS: This model could create clinical impact as an in vitro diagnostic tool for rapid assessment of tumor needle biopsies to confirm metastatic tumors, their invasiveness, and allow high-throughput drug screening providing rapid development of personalized therapies. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1471-2407-14-825) contains supplementary material, which is available to authorized users

An Assessment of the Model of Concentration Addition for Predicting the Estrogenic Activity of Chemical Mixtures in Wastewater Treatment Works Effluents

The effects of simple mixtures of chemicals, with similar mechanisms of action, can be predicted using the concentration addition model (CA). The ability of this model to predict the estrogenic effects of more complex mixtures such as effluent discharges, however, has yet to be established. Effluents from 43 U.K. wastewater treatment works were analyzed for the presence of the principal estrogenic chemical contaminants, estradiol, estrone, ethinylestradiol, and nonylphenol. The measured concentrations were used to predict the estrogenic activity of each effluent, employing the model of CA, based on the relative potencies of the individual chemicals in an in vitro recombinant yeast estrogen screen (rYES) and a short-term (14-day) in vivo rainbow trout vitellogenin induction assay. Based on the measured concentrations of the four chemicals in the effluents and their relative potencies in each assay, the calculated in vitro and in vivo responses compared well and ranged between 3.5 and 87 ng/L of estradiol equivalents (E2 EQ) for the different effluents. In the rYES, however, the measured E2 EQ concentrations in the effluents ranged between 0.65 and 43 ng E2 EQ/L, and they varied against those predicted by the CA model. Deviations in the estimation of the estrogenic potency of the effluents by the CA model, compared with the measured responses in the rYES, are likely to have resulted from inaccuracies associated with the measurement of the chemicals in the extracts derived from the complex effluents. Such deviations could also result as a consequence of interactions between chemicals present in the extracts that disrupted the activation of the estrogen response elements in the rYES. E2 EQ concentrations derived from the vitellogenic response in fathead minnows exposed to a series of effluent dilutions were highly comparable with the E2 EQ concentrations derived from assessments of the estrogenic potency of these dilutions in the rYES. Together these data support the use of bioassays for determining the estrogenic potency of WwTW effluents, and they highlight the associated problems for modeling approaches that are reliant on measured concentrations of estrogenic chemicals