Canine reference intervals for coagulation markers using the STA Satellite and the STA-R Evolution analyzers

The aim of the current study was to determine canine reference intervals for prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen, and antithrombin (AT) according to international recommendations. The STA Satellite coefficients of variation of within-laboratory imprecision were 3.9%, 1.3%, 6.9%, and 5.1% for PT, APTT, fibrinogen, and AT, respectively. At 4uC, citrated specimens were stable up to 8 hr for whole blood and 36 hr for plasma, except for APTT, which increased slightly (<1 sec). Nonparametric reference intervals determined in citrated plasma from 139 healthy fasting purebred dogs were 6.9–8.8 sec, 13.1–17.2 sec, 1.24–4.30 g/l, and 104–188% for PT, APTT, fibrinogen, and AT, respectively. Based on Passing–Bablok comparison between STA Satellite and STA-R Evolution using 60 frozen specimens from a canine plasma bank, the corresponding reference intervals were transferred to the STA-R Evolution: 7.1–9.2 sec, 12.9–17.3 sec, 1.20–4.43 g/l, and 94–159% for PT, APTT, fibrinogen, and AT, respectively

Neuromorphic weighted sum with magnetic skyrmions

Integrating magnetic skyrmion properties into neuromorphic computing promises advancements in hardware efficiency and computational power. However, a scalable implementation of the weighted sum of neuron signals, a core operation in neural networks, has yet to be demonstrated. In this study, we exploit the non-volatile and particle-like characteristics of magnetic skyrmions, akin to synaptic vesicles and neurotransmitters, to perform this weighted sum operation in a compact, biologically-inspired manner. To this aim, skyrmions are electrically generated in numbers proportional to the input with an efficiency given by a non-volatile weight. These chiral particles are then directed using localized current injections to a location where their presence is quantified through non-perturbative electrical measurements. Our experimental demonstration, currently with two inputs, can be scaled to accommodate multiple inputs and outputs using a crossbar array design, potentially nearing the energy efficiency observed in biological systems.Comment: 12 pages, 5 figure

Réadaptation et insuffisance cardiaque en Basse-Normandie

CAEN-BU Médecine pharmacie (141182102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Enhanced stability in spin transfer nanopillars due to a Fe/Gd/Fe trilayer

A sharp antiferromagnetic boundary of Fe/Gd is found to affect notoriously the critical current for spin transfer torque (STT). Transport measurements performed on nano-patterned spin valves show that when a Fe/Gd/Fe is added as a top layer, the effect of spin transfer on the free layer is dramatically reduced. The critical current increases up to one order of magnitude at 10 K and five times at room temperature. We show that this increase cannot be fully explained by the macrospin approximation and we argue that it is due to a torque at the Gd/Fe interface that opposes the STT in the free layer.Ministerio de Ciencia e Innovación (España)Depto. de Física de MaterialesFac. de Ciencias FísicasTRUEpu

Control of the magnetic anisotropy in multirepeat Pt/Co/Al heterostructures using magnetoionic gating

Controlling magnetic properties through the application of an electric field is a significant challenge in modern nanomagnetism. In this study, we investigate the magnetoionic control of magnetic anisotropy in the topmost Co layer in Ta/Pt/[Co/Al/Pt]n/Co/Al/AlOx multilayer stacks comprising n + 1 Co layers and its impact on the magnetic properties of the multilayers. We demonstrate that the perpendicular magnetic anisotropy can be reversibly quenched through gate-driven oxidation of the intermediary Al layer between Co and AlOx, enabling dynamic control of the magnetic layers contributing to the out-of-plane remanence— varying between n and n + 1. For multilayer configurations with n = 2 and n = 4, we observe reversible and nonvolatile additions of 1/3 and 1/5, respectively, to the anomalous Hall-effect amplitude based on the applied gate voltage. Magnetic imaging reveals that the gate-induced spin-reorientation transition occurs through the propagation of a single 90◦ magnetic domain wall separating the perpendicular and in-plane anisotropy states. In the five-repetition multilayer, the modification leads to a doubling of the period of the magnetic domains at remanence. These results demonstrate that the magnetoionic control of the anisotropy of a single magnetic layer can be used to control the magnetic properties of coupled multilayer systems, extending beyond the gating effects on a single magnetic layer