Effect on smoking quit rate of telling patients their lung age: the Step2quit randomised controlled trial

Objective To evaluate the impact of telling patients their estimated spirometric lung age as an incentive to quit smoking.Design Randomised controlled trial.Setting Five general practices in Hertfordshire, England.Participants 561 current smokers aged over 35.Intervention All participants were offered spirometric assessment of lung function. Participants in intervention group received their results in terms of "lung age" (the age of the average healthy individual who would perform similar to them on spirometry). Those in the control group received a raw figure for forced expiratory volume at one second (FEV1). Both groups were advised to quit and offered referral to local NHS smoking cessation services.Main outcome measures The primary outcome measure was verified cessation of smoking by salivary cotinine testing 12 months after recruitment. Secondary outcomes were reported changes in daily consumption of cigarettes and identification of new diagnoses of chronic obstructive lung disease.Results Follow-up was 89%. Independently verified quit rates at 12 months in the intervention and control groups, respectively, were 13.6% and 6.4% (difference 7.2%, P=0.005, 95% confidence interval 2.2% to 12.1%; number needed to treat 14). People with worse spirometric lung age were no more likely to have quit than those with normal lung age in either group. Cost per successful quitter was estimated at 280 pound ((euro) 365, $556). A new diagnosis of obstructive lung disease was made in 17% in the intervention group and 14% in the control group; a total of 16% (89/561) of participants.Conclusion Telling smokers their lung age significantly improves the likelihood of them quitting smoking, but the mechanism by which this intervention achieves its effect is unclear.Trial registration National Research Register N0096173751

The use of LANDSAT digital data and computer-implemented techniques for an agricultural application

Agricultural applications procedures are described for use of LANDSAT digital data and other digitalized data (e.g., soils). The results of having followed these procedures are shown in production estimates for cotton and soybeans in Washington County, Mississippi. Examples of output products in both line printer and map formats are included, and a product adequacy assessment is made

Two-fluid dynamics for a Bose-Einstein condensate out of local equilibrium with the non-condensate

We extend our recent work on the two-fluid hydrodynamics of a Bose-condensed gas by including collisions involving both condensate and non-condensate atoms. These collisions are essential for establishing a state of local thermodynamic equilibrium between the condensate and non-condensate. Our theory is more general than the usual Landau two-fluid theory, to which it reduces in the appropriate limit, in that it allows one to describe situations in which a state of complete local equilibrium between the two components has not been reached. The exchange of atoms between the condensate and non-condensate is associated with a new relaxational mode of the gas.Comment: 4 pages, revtex, 1 postscript figure, Fig.1 has been correcte

Quantum Fluctuations in Dipolar Bose Gases

We investigate the influence of quantum fluctuations upon dipolar Bose gases by means of the Bogoliubov-de Gennes theory. Thereby, we make use of the local density approximation to evaluate the dipolar exchange interaction between the condensate and the excited particles. This allows to obtain the Bogoliubov spectrum analytically in the limit of large particle numbers. After discussing the condensate depletion and the ground-state energy correction, we derive quantum corrected equations of motion for harmonically trapped dipolar Bose gases by using superfluid hydrodynamics. These equations are subsequently applied to analyze the equilibrium configuration, the low-lying oscillation frequencies, and the time-of-flight dynamics. We find that both atomic magnetic and molecular electric dipolar systems offer promising scenarios for detecting beyond mean-field effects.Comment: Published in PR

Research and development in CdS photovoltaic cells Third quarterly report, 29 Dec. 1965 - 29 Mar. 1966

Barrier formation studies of copper sulfide and cadmium sulfide in photovoltaic cell

Trunk muscle activity during drop jump performance in adolescent athletes with back pain

It was with great interest we read the recently published article “Trunk Muscle Activity during Drop Jump Performance in Adolescent Athletes with Back Pain.” Investigating back pain (BP) in adolescents is commendable as there is growing evidence that for many, an experience of BP as early as 14 years of age may relate to ongoing pain in adulthood (Coenen et al., 2017). Indeed, the conventional narrative is changing as individual physical factors such as posture, use of schoolbags, and hypermobility are only weakly associated with adolescent BP. Rather, factors which predict BP at a young age are considered to be multi-dimensional and include gender, negative BP beliefs and poor mental health (O\u27Sullivan et al., 2017; Smith et al., 2017). Mueller et al. (2017) have focused on a single physical factor (trunk muscle activation patterns) drawing inferences regarding BP prevention and treatment. This article prompts consideration of three essential aspects regarding research design and interpretation of findings: 1. Interpreting results from cross-sectional designs 2. Interpreting pain-related differences in motor behavior 3. Translating and conveying scientific results to the end-user (patients, healthcare professionals and policy makers)

Systematic review of the current status of cadaveric simulation for surgical training

Background: There is growing interest in and provision of cadaveric simulation courses for surgical trainees. This is being driven by the need to modernize and improve the efficiency of surgical training within the current challenging training climate. The objective of this systematic review is to describe and evaluate the evidence for cadaveric simulation in postgraduate surgical training. Methods: A PRISMA‐compliant systematic literature review of studies that prospectively evaluated a cadaveric simulation training intervention for surgical trainees was undertaken. All relevant databases and trial registries were searched to January 2019. Methodological rigour was assessed using the widely validated Medical Education Research Quality Index (MERSQI) tool. Results: A total of 51 studies were included, involving 2002 surgical trainees across 69 cadaveric training interventions. Of these, 22 assessed the impact of the cadaveric training intervention using only subjective measures, five measured impact by change in learner knowledge, and 23 used objective tools to assess change in learner behaviour after training. Only one study assessed patient outcome and demonstrated transfer of skill from the simulated environment to the workplace. Of the included studies, 67 per cent had weak methodology (MERSQI score less than 10·7). Conclusion: There is an abundance of relatively low‐quality evidence showing that cadaveric simulation induces short‐term skill acquisition as measured by objective means. There is currently a lack of evidence of skill retention, and of transfer of skills following training into the live operating theatre

Formation of Protoplanets from Massive Planetesimals in Binary Systems

More than half of stars reside in binary or multiple star systems and many planets have been found in binary systems. From theoretical point of view, however, whether or not the planetary formation proceeds in a binary system is a very complex problem, because secular perturbation from the companion star can easily stir up the eccentricity of the planetesimals and cause high-velocity, destructive collisions between planetesimals. Early stage of planetary formation process in binary systems has been studied by restricted three-body approach with gas drag and it is commonly accepted that accretion of planetesimals can proceed due to orbital phasing by gas drag. However, the gas drag becomes less effective as the planetesimals become massive. Therefore it is still uncertain whether the collision velocity remains small and planetary accretion can proceed, once the planetesimals become massive. We performed {\it N}-body simulations of planetary formation in binary systems starting from massive planetesimals whose size is about 100-500 km. We found that the eccentricity vectors of planetesimals quickly converge to the forced eccentricity due to the coupling of the perturbation of the companion and the mutual interaction of planetesimals if the initial disk model is sufficiently wide in radial distribution. This convergence decreases the collision velocity and as a result accretion can proceed much in the same way as in isolated systems. The basic processes of the planetary formation, such as runaway growth and oligarchic growth and final configuration of the protoplanets are essentially the same in binary systems and single star systems, at least in the late stage where the effect of gas drag is small.Comment: 26pages, 11 figures. ApJ accepte

A submillimetre wavelength spectral line search of the Orion molecular cloud core

A submillimetre wavelength molecular line search of the Orion molecular cloud has been made covering a total of about 5 percent of the frequency range 342.8 - 358.6 GHz. This search, coupled with the authors' previous observations of submillimetre transitions in this cloud, has led to the detection of 22 transitions of 14 molecular species, of which 16 are reported here for the first time. No unidentified lines have been detected in the present search. Mapping observations have been obtained for several of the lines and, in the case of H2CO the authors have been able to compare the present data with that obtained from other telescopes, to estimate the density and abundance in the emitting region

Combined liver-kidney transplantation: Analysis of patients with preformed lymphocytotoxic antibody

In this report, we address combined liver-kidney transplantation, with particular attention to the apparent phenomenon of protection of kidney allografts to antibody mediated destruction by liver allografts. Four patients were found to have positive crossmatch before the liver phase of the combined transplant (pre-OT/KT samples). These positive crossmatches were due entirely to anti-HLA class I antibodies, as demonstrated by their removal by immunoabsorption on pololed platelets. In three of these patients, post-OT/pre-KT samples showed a conversion to a negative crossmatch (in the fourth patient this was not done). A kidney allograft, harveted from the same donor, was then placed into the recipient, and in patients no. 3, 7, and 12, good initial function was noted. In one of these patients was there evidence of hyperacute rejection. Post-OT/KT samples were collected in patients no. 3, 7, and 8, and then analyzed for the reappearance of donor specific lymphocytotoxic antibodies in the posttransplant period (data on patient no. 12 was not available at time of preparation). Lymphocytotoxic antibodies with donor specificity could not be detected in any of the samples during the first week posttransplant. The decrease in %PRA and conversion of a positive to negative crossmatch following liver transplantation was correlated to the HLA specificty of the antibody found in the pretransplant serum and the HLA type of the tranplanted organs. In the two instances where an HLA specificity could be determined by panel analysis, transplantation with donor organs bearing these HLA specificities led to a specific disppearance of these antibodies during the postransplant phase