161 research outputs found

    Note of ARMA REF Audit Compliance Meeting 22nd August 2019

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    Note of ARMA REF Audit Compliance Meeting 22nd August 2019

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    No abstract available

    Selecting high quality dual language texts for young children in multicultural contexts: A uae case

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    © 2019, Western Australian Institute for Educational Research Inc.. All rights reserved. Bilingual literature for children is valuable in encouraging literacy in second language learners. Stories can enhance vocabulary and language abilities, learning encounters, subject content, social aptitude, and other skills in the early reader through text as well as illustrations. This paper explores issues in selecting quality dual language picture books with the aim of deepening understanding of what is meant by ‘quality’ dual language books, in terms of text quality, specifically translation accuracy, cultural relevance and book information. Four English/Arabic bilingual children books were evaluated by three raters from different backgrounds. A mixed method approach was followed to combine qualitative evaluations of these books with quantitative scores based on inter-rater reliability. Findings highlight the importance of interplay between picture and verbal text in picture books, urging educators to give more explicit attention to illustrations in any evaluation of text quality in picture books

    English Medium Instruction and the potential of translanguaging practices in higher education

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    Abstract In the UAE, although Arabic is the first and official language (L1), English has become the medium of instruction and the language of discourse in higher education in most subject domains. The pedagogical implications of English Medium Instruction (EMI) in the specific context of higher education in the UAE are not well understood, and research is needed to establish what kinds of support speakers of English as a second or additional language (L2) might need to fully access content knowledge in English without burdening learning. Our empirical work hypothesizes that learning content through L2 may lead to more favourable results if the L1 is explicitly drawn upon as a resource in addition to the L2. This study provided undergraduate students with learning materials in three experimental conditions (Arabic-only, English-only, and dual language). Students’ performance was then assessed in three areas of linguistic competence, namely translation into Arabic of a list of English words and phrases, comprehension of an English written text, and translation into Arabic of English words and phrases in context. A series of one way ANOVAs and post-hoc comparisons were carried out to determine differences between the three conditions. The study confirms that overall, for students with an intermediate language level, the presentation of dual language reading materials has a greater impact on their outcomes in comparison with the presentation of reading materials in the L1 or L2 only. This highlights the critical need for raising awareness of translanguaging practices in EMI contexts

    Associations Among Healthcare Utilization and Binge Drinking

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    Objective. To examine associations among routine healthcare services and binge drinking in Vermont adults. Methods. We analyzed a cross-sectional sample of randomly selected 6516 adults who participated in the self-reported 2017 Vermont Behavioral Risk Surveillance System survey. We estimated odds ratios for responses indicative of binge drinking in association with length of time since last routine checkup using a bivariate logistic regression model. Results. Participants who reported binge drinking were 31% (OR = 0.69, 95% confidence interval [CI] = 0.56, 0.83) less likely to engage in a healthcare visit within the past year controlling for age, employment status, annual household income, and sex with all tests holding statistical significance (P ≤ 0.05). Conclusion. Findings indicated that binge drinking coincided with a decrease in likelihood of using routine healthcare services within one year. Policy recommendations. Binge drinking remains a costly form of substance misuse, physically to the individual and financially to the public. Addressing perceived barriers and encouraging those who binge drink to seek annual routine healthcare services is vital to ensuring these at-risk populations receive car

    Potentiometric MRI of a Superconcentrated Lithium Electrolyte: Testing the Irreversible Thermodynamics Approach.

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    Superconcentrated electrolytes, being highly thermodynamically nonideal, provide a stringent proving ground for continuum transport theories. Herein, we test an ostensibly complete model of LiPF6 in ethyl-methyl carbonate (EMC) based on the Onsager-Stefan-Maxwell theory from irreversible thermodynamics. We perform synchronous magnetic resonance imaging (MRI) and chronopotentiometry to examine how superconcentrated LiPF6:EMC responds to galvanostatic polarization and open-circuit relaxation. We simulate this experiment using an independently parametrized model with six composition-dependent electrolyte properties, quantified up to saturation. Spectroscopy reveals increasing ion association and solvent coordination with salt concentration. The potentiometric MRI data agree closely with the predicted ion distributions and overpotentials, providing a completely independent validation of the theory. Superconcentrated electrolytes exhibit strong cation-anion interactions and extreme solute-volume effects that mimic elevated lithium transference. Our simulations allow surface overpotentials to be extracted from cell-voltage data to track lithium interfaces. Potentiometric MRI is a powerful tool to illuminate electrolytic transport phenomena

    Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene

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    The genomes of RNA and small DNA viruses of vertebrates display significant suppression of CpG dinucleotide frequencies. Artificially increasing dinucleotide frequencies results in substantial attenuation of virus replication, suggesting that these compositional changes may facilitate recognition of non-self RNA sequences. Recently, the interferon inducible protein ZAP, was identified as the host factor responsible for sensing CpG in viral RNA, through direct binding and possibly downstream targeting for degradation. Using an arrayed interferon stimulated gene expression library screen, we identified ZAPS, and its associated factor TRIM25, as inhibitors of human cytomegalovirus (HCMV) replication. Exogenous expression of ZAPS and TRIM25 significantly reduced virus replication while knockdown resulted in increased virus replication. HCMV displays a strikingly heterogeneous pattern of CpG representation with specific suppression of CpG motifs within the IE1 major immediate early transcript which is absent in subsequently expressed genes. We demonstrated that suppression of CpG dinucleotides in the IE1 gene allows evasion of inhibitory effects of ZAP. We show that acute virus replication is mutually exclusive with high levels of cellular ZAP, potentially explaining the higher levels of CpG in viral genes expressed subsequent to IE1 due to the loss of pressure from ZAP in infected cells. Finally, we show that TRIM25 regulates alternative splicing between the ZAP short and long isoforms during HCMV infection and interferon induction, with knockdown of TRIM25 resulting in decreased ZAPS and corresponding increased ZAPL expression. These results demonstrate for the first time that ZAP is a potent host restriction factor against large DNA viruses and that HCMV evades ZAP detection through suppression of CpG dinucleotides within the major immediate early 1 transcript. Furthermore, TRIM25 is required for efficient upregulation of the interferon inducible short isoform of ZAP through regulation of alternative splicing
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