19 research outputs found

    Performance characteristics of several divergent-shroud aircraft ejectors

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    Performance characteristics of several divergent- shroud aircraft ejector

    Alternating North‐South Brightness Ratio of Ganymede's Auroral Ovals: Hubble Space Telescope Observations Around the Juno PJ34 Flyby

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    peer reviewedWe report results of Hubble Space Telescope observations from Ganymede's orbitally trailing side which were taken around the flyby of the Juno spacecraft on 7 June 2021. We find that Ganymede's northern and southern auroral ovals alternate in brightness such that the oval facing Jupiter's magnetospheric plasma sheet is brighter than the other one. This suggests that the generator that powers Ganymede's aurora is the momentum of the Jovian plasma sheet north and south of Ganymede's magnetosphere. Magnetic coupling of Ganymede to the plasma sheet above and below the moon causes asymmetric magnetic stresses and electromagnetic energy fluxes ultimately powering the auroral acceleration process. No clear statistically significant timevariability of the auroral emission on short time scales of 100s could be resolved. We show that electron energy fluxes of several tens of mW m−2 are required for its OI 1,356 Å emission making Ganymede a very poor auroral emitter

    A multi-targeted approach to suppress tumor-promoting inflammation

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    Cancers harbor significant genetic heterogeneity and patterns of relapse following many therapies are due to evolved resistance to treatment. While efforts have been made to combine targeted therapies, significant levels of toxicity have stymied efforts to effectively treat cancer with multi-drug combinations using currently approved therapeutics. We discuss the relationship between tumor-promoting inflammation and cancer as part of a larger effort to develop a broad-spectrum therapeutic approach aimed at a wide range of targets to address this heterogeneity. Specifically, macrophage migration inhibitory factor, cyclooxygenase-2, transcription factor nuclear factor-κB, tumor necrosis factor alpha, inducible nitric oxide synthase, protein kinase B, and CXC chemokines are reviewed as important antiinflammatory targets while curcumin, resveratrol, epigallocatechin gallate, genistein, lycopene, and anthocyanins are reviewed as low-cost, low toxicity means by which these targets might all be reached simultaneously. Future translational work will need to assess the resulting synergies of rationally designed antiinflammatory mixtures (employing low-toxicity constituents), and then combine this with similar approaches targeting the most important pathways across the range of cancer hallmark phenotypes

    Preliminary Internal Performance Data for a Variable-Ejector Assembly on the XJ79-GE-1 Turbojet Engine

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    Internal performance of an XJ79-GE-1 variable ejector was experimentally determined with the primary nozzle in a representative nonafterburning position. Jet-thrust and air-handling data were obtained in quiescent air for 11 selected ejector configurations over a wide range of operation. Additional data, at specific operating conditions, were obtained which indicate the ejector diameter ratio for peak jet-thrust performance. The experimental ejector data are presented in both graphical and tabulated form
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