27,004 research outputs found
Helicopter Wake Encounters in the Context of RECAT-EU
This work presents a first attempt to apply the RECAT-EU (European Wake Turbulence Categorisation and Separation Minima) methodology of fixed-wing aircraft separation to helicopters. The approach is based on a classification of helicopters in categories using their rotor diameter and weight combined with wake comparisons between different classes of fixed-wing aircraft and helicopters. Where necessary the upset caused by a wake encounter to a simple helicopter model is used to establish safe separation distances. The work is based on a very limited amount of data for wake strengths but shows that the principles of the RECAT-EU methodology are directly applicable to helicopters at least for landing and take-off. This research calls for further measurements of helicopter wakes with modern methods so that the suggested separation distances can be further ascertained and ultimately refined allowing for better and safer integration of fixed and rotary-wing traffic at airports
Character formulas for the operad of two compatible brackets and for the bihamiltonian operad
We compute dimensions of the components for the operad of two compatible
brackets and for the bihamiltonian operad. We also obtain character formulas
for the representations of the symmetric groups and the group in these
spaces.Comment: 24 pages, accepted by Functional Analysis and its Applications, a few
typos correcte
Energy conditions outside a dielectric ball
We show analytically that the vacuum electromagnetic stress-energy tensor
outside a ball with constant dielectric constant and permeability always obeys
the weak, null, dominant, and strong energy conditions. There are still no
known examples in quantum field theory in which the averaged null energy
condition in flat spacetime is violated.Comment: 12 pages, RevTex
Casimir Effects in Renormalizable Quantum Field Theories
We review the framework we and our collaborators have developed for the study
of one-loop quantum corrections to extended field configurations in
renormalizable quantum field theories. We work in the continuum, transforming
the standard Casimir sum over modes into a sum over bound states and an
integral over scattering states weighted by the density of states. We express
the density of states in terms of phase shifts, allowing us to extract
divergences by identifying Born approximations to the phase shifts with low
order Feynman diagrams. Once isolated in Feynman diagrams, the divergences are
canceled against standard counterterms. Thus regulated, the Casimir sum is
highly convergent and amenable to numerical computation. Our methods have
numerous applications to the theory of solitons, membranes, and quantum field
theories in strong external fields or subject to boundary conditions.Comment: 27 pp., 11 EPS figures, LaTeX using ijmpa1.sty; email correspondence
to R.L. Jaffe ; based on talks presented by the authors at
the 5th workshop `QFTEX', Leipzig, September 200
Noise-Activated Escape from a Sloshing Potential Well
We treat the noise-activated escape from a one-dimensional potential well of
an overdamped particle, to which a periodic force of fixed frequency is
applied. We determine the boundary layer behavior, and the physically relevant
length scales, near the oscillating well top. We show how stochastic behavior
near the well top generalizes the behavior first determined by Kramers, in the
case without forcing. Both the case when the forcing dies away in the weak
noise limit, and the case when it does not, are examined. We also discuss the
relevance of various scaling regimes to recent optical trap experiments.Comment: 9 pages, no figures, REVTeX, expanded versio
Exact solutions for the spatial de Vaucouleurs and Sersic laws and related quantities
Using the Mathematica package, we find exact analytical expressions for the
so-called de-projected De Vaucouleurs and Sersic laws as well as for related
spatial (3D) quantities, such the mass, gravitational potential, the total
energy and the central velocity dispersion, generally involved in astronomical
calculations expressed in terms of the Meijer G functions.Comment: 11 pages, accepted in A
Human papillomavirus E2 regulates SRSF3 (SRp20) to promote capsid protein expression in infected differentiated keratinocytes
The human papillomavirus (HPV) life cycle is tightly linked to differentiation of the infected epithelial cell suggesting a sophisticated interplay between host cell metabolism and virus replication. Previously we demonstrated in differentiated keratinocytes in vitro and in vivo that HPV16 infection caused increased levels of the cellular SR splicing factors (SRSFs) SRSF1 (ASF/SF2), SRSF2 (SC35) and SRSF3 (SRp20). Moreover, the viral E2 transcription and replication factor that is expressed at high levels in differentiating keratinocytes could bind and control activity of the SRSF1 gene promoter. Here we reveal that E2 proteins of HPV16 and HPV31 control expression of SRSFs 1, 2 and 3 in a differentiation-dependent manner. E2 has the greatest trans-activation effect on expression of SRSF3. siRNA depletion experiments in two different models of the HPV16 life cycle (W12E and NIKS16) and one model of the HPV31 life cycle (CIN612-9E) revealed that only SRSF3 contributed significantly to regulation of late events in the virus life cycle. Increased levels of SRSF3 are required for L1 mRNA and capsid protein expression. Capsid protein expression was regulated specifically by SRSF3 and appeared independent of other SRSFs. Taken together these data suggest a significant role of the HPV E2 protein in regulating late events in the HPV life cycle through transcriptional regulation of SRSF3 expression.
IMPORTANCE Human papillomavirus replication is accomplished in concert with differentiation of the infected epithelium. Virus capsid protein expression is confined to the upper epithelial layers so as to avoid immune detection. In this study we demonstrate that the viral E2 transcription factor activates the promoter of the cellular SRSF3 RNA processing factor. SRSF3 is required for expression of the E4̂L1 mRNA and so controls expression of the HPV L1 capsid protein. Thus we reveal a new dimension of virus-host interaction crucial for production of infectious virus. SRSF proteins are known drug targets. Therefore, this study provides an excellent basis for developing strategies to regulate capsid protein production in the infected epithelium and production of new virions
Experimental Design for the Gemini Planet Imager
The Gemini Planet Imager (GPI) is a high performance adaptive optics system
being designed and built for the Gemini Observatory. GPI is optimized for high
contrast imaging, combining precise and accurate wavefront control, diffraction
suppression, and a speckle-suppressing science camera with integral field and
polarimetry capabilities. The primary science goal for GPI is the direct
detection and characterization of young, Jovian-mass exoplanets. For plausible
assumptions about the distribution of gas giant properties at large semi-major
axes, GPI will be capable of detecting more than 10% of gas giants more massive
than 0.5 M_J around stars younger than 100 Myr and nearer than 75 parsecs. For
systems younger than 1 Gyr, gas giants more massive than 8 M_J and with
semi-major axes greater than 15 AU are detected with completeness greater than
50%. A survey targeting young stars in the solar neighborhood will help
determine the formation mechanism of gas giant planets by studying them at ages
where planet brightness depends upon formation mechanism. Such a survey will
also be sensitive to planets at semi-major axes comparable to the gas giants in
our own solar system. In the simple, and idealized, situation in which planets
formed by either the "hot-start" model of Burrows et al. (2003) or the core
accretion model of Marley et al. (2007), a few tens of detected planets are
sufficient to distinguish how planets form.Comment: 15 pages, 9 figures, revised after referee's comments and resubmitted
to PAS
The exact cosmological solution to the dynamical equations for the Bianchi IX model
Quantum geometrodynamics in extended phase space describes phenomenologically
the integrated system ``a physical object + observation means (a gravitational
vacuum condensate)''. The central place in this version of QGD belongs to the
Schrodinger equation for a wave function of the Universe. An exact solution to
the ``conditionally-classical'' set of equations in extended phase space for
the Bianchi-IX model and the appropriate solution to the Schrodinger equation
are considered. The physical adequacy of the obtained solutions to existing
concepts about possible cosmological scenarios is demonstrated. The
gravitational vacuum condensate is shown to be a cosmological evolution factor.Comment: LaTeX, 14 pages, to be published in Int. J. Mod. Phys.
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