Asperger's syndrome: learner characteristics and teaching strategies

Students with Asperger's syndrome present a particular challenge for their parents, teachers, and peers. Therefore it is important for teachers working in inclusive settings to become aware of the unique needs of these students. In this paper, challenges for students with Asperger's syndrome are discussed in terms of five aspects; communication, motor clumsiness, obsessional interests, attention and social skills. These characteristics are discussed in a wav that will facilitate teachers' understanding of the difficulties associated with student participation in the school environment. Challenges for teachers are discussed under the headings: inclusive schooling; need for a structured program; behaviour management; communication; and creativity in planning. Adaptive and compensatory strategies for teachers are described which will facilitate learning and participation of students with Asperger's syndrome in the regular classroom

Realist evaluation for programs designed to reduce demand and harms of substance misuse at the community level in Australian remote Indigenous community settings

This thesis reviewed NHMRC-funded, community-level substance misuse interventions, documenting: outcomes; study designs; implicit program theory; and assumptions. Data from one intervention project, targeting cannabis misuse in Cape York, exemplified common evaluation constraints, and informed hypothetical context-mechanism-outcome clusters for a plausible program theory and proposed theory-driven evaluation

Teachers’ Perceptions and Experiences during an Annual Performance and Development Cycle

In this study, the perceptions and experiences of eighteen teachers across three primary schools in Victoria, Australia, were examined as they participated in an annual performance and development cycle, guided by the Australian Teacher Performance and Development Framework. The study sought to investigate teachers’ experiences and perceptions of the cycle to understand the aspects perceived as valuable to these teachers. Semi-structured interviews and focus groups were held with teachers at the beginning and end of each school’s annual performance and development cycle, and responses were thematically analysed. Findings suggest that school leaders perform a critical role in the success of performance and development processes, and cultivating a culture of learning and development with a focus on individual and collective improvement helped teachers feel connected to these processes and empowered as learners. The findings of this study have implications for the individual and collective nature of performance and development. Based on research and findings, a five-step model is proposed to support the design and implementation of meaningful teacher performance and development processes

The Invigoration of Deep Convective Clouds Over the Atlantic: Aerosol Effect, Meteorology or Retrieval Artifact?

Associations between cloud properties and aerosol loading are frequently observed in products derived from satellite measurements. These observed trends between clouds and aerosol optical depth suggest aerosol modification of cloud dynamics, yet there are uncertainties involved in satellite retrievals that have the potential to lead to incorrect conclusions. Two of the most challenging problems are addressed here: the potential for retrieved aerosol optical depth to be cloud-contaminated, and as a result, artificially correlated with cloud parameters; and the potential for correlations between aerosol and cloud parameters to be erroneously considered to be causal. Here these issues are tackled directly by studying the effects of the aerosol on convective clouds in the tropical Atlantic Ocean using satellite remote sensing, a chemical transport model, and a reanalysis of meteorological fields. Results show that there is a robust positive correlation between cloud fraction or cloud top height and the aerosol optical depth, regardless of whether a stringent filtering of aerosol measurements in the vicinity of clouds is applied, or not. These same positive correlations emerge when replacing the observed aerosol field with that derived from a chemical transport model. Model-reanalysis data is used to address the causality question by providing meteorological context for the satellite observations. A correlation exercise between the full suite of meteorological fields derived from model reanalysis and satellite-derived cloud fields shows that observed cloud top height and cloud fraction correlate best with model pressure updraft velocity and relative humidity. Observed aerosol optical depth does correlate with meteorological parameters but usually different parameters from those that correlate with observed cloud fields. The result is a near-orthogonal influence of aerosol and meteorological fields on cloud top height and cloud fraction. The results strengthen the case that the aerosol does play a role in invigorating convective clouds

Neural patterns of the implicit association test

The Implicit Association Test (IAT) is a reaction time based categorization task that measures the differential associative strength between bipolar targets and evaluative attribute concepts as an approach to indexing implicit beliefs or biases. An open question exists as to what exactly the IAT measures, and here EEG (Electroencephalography) has been used to investigate the time course of ERPs (Event-related Potential) indices and implicated brain regions in the IAT. IAT-EEG research identifies a number of early (250–450 ms) negative ERPs indexing early-(pre-response) processing stages of the IAT. ERP activity in this time range is known to index processes related to cognitive control and semantic processing. A central focus of these efforts has been to use IAT-ERPs to delineate the implicit and explicit factors contributing to measured IAT effects. Increasing evidence indicates that cognitive control (and related top-down modulation of attention/perceptual processing) may be components in the effective measurement of IAT effects, as factors such as physical setting or task instruction can change an IAT measurement. In this study we further implicate the role of proactive cognitive control and top-down modulation of attention/perceptual processing in the IAT-EEG. We find statistically significant relationships between D-score (a reaction-time based measure of the IAT-effect) and early ERP-time windows, indicating where more rapid word categorizations driving the IAT effect are present, they are at least partly explainable by neural activity not significantly correlated with the IAT measurement itself. Using LORETA, we identify a number of brain regions driving these ERP-IAT relationships notably involving left-temporal, insular, cingulate, medial frontal and parietal cortex in time regions corresponding to the N2- and P3-related activity. The identified brain regions involved with reduced reaction times on congruent blocks coincide with those of previous studies

The connexin mimetic peptide Gap27 and Cx43-Knockdown reveal differential roles for Connexin43 in wound closure events in skin model systems

In the epidermis, remodelling of Connexin43 is a key event in wound closure. However, controversy between the role of connexin channel and non-channel functions exist. We compared the impact of SiRNA targeted to Connexin43 and the connexin mimetic peptide Gap27 on scrape wound closure rates and hemichannel signalling in adult keratinocytes (AK) and fibroblasts sourced from juvenile foreskin (JFF), human neonatal fibroblasts (HNDF) and adult dermal tissue (ADF). The impact of these agents, following 24 h exposure, on (encoding Connexin43), and gene expression, and Connexin43 and pSmad3 protein expression levels, were examined by qPCR and Western Blot respectively. In all cell types Gap27 (100-100 μM) attenuated hemichannel activity. In AK and JFF cells, Gap27 (100 nM-100 μM) enhanced scrape wound closure rates by ~50% but did not influence movement in HNDF or ADF cells. In both JF and AK cells, exposure to Gap27 for 24 h reduced the level of Cx43 protein expression but did not affect the level in ADF and HNDF cells. Connexin43-SiRNA enhanced scrape wound closure in all the cell types under investigation. In HDNF and ADF, Connexin43-SiRNA enhanced cell proliferation rates, with enhanced proliferation also observed following exposure of HDNF to Gap27. By contrast, in JFF and AK cells no changes in proliferation occurred. In JFF cells, Connexin43-SiRNA enhanced levels and in JFF and ADF cells both Connexin43-SiRNA and Gap27 enhanced pSmad3 protein expression levels. We conclude that Connexin43 signalling plays an important role in cell migration in keratinocytes and foreskin derived fibroblasts, however, different pathways are evoked and in dermal derived adult and neonatal fibroblasts, inhibition of Connexin43 signalling plays a more significant role in regulating cell proliferation than cell migration

Supporting Home-School Partnerships during Stage 6 in the New England Region

Stage 6, Year 11 and 12, are the last two years of secondary school in New South Wales. It is a challenging time for students and for those who live with them. This project and its associated program 'Senior Success' is designed to facilitate a strong home-school partnership, a partnership which can scaffold a young person as they complete their school education and take their first steps into the world beyond. This project is about a three way partnership Home-School-Student. It is about valuing the equal communication of information to all stakeholders and facilitating a scaffolding of the student which recognises and values the contribution of home and the emerging adult student to successful school completion. This project focusses upon effective communication of the expectations of Stage 6; the challenges of Stage 6 and strategies to maximise academic and social outcomes

Review of the Aberdeen Problem Solving Approach - Summary Briefing

A 6 page summary briefing of the full report, 'Review of the Aberdeen Problem-Solving Approach' (2018) by Jane Eunson, Lorraine Murray, Hannah Graham, Margaret Malloch and Gill McIvor. The Scottish Government commissioned Ipsos MORI Scotland and the Scottish Centre for Crime and Justice Research/University of Stirling to conduct an independent Review of the PSA between August 2017 and January 2018

Review of the Aberdeen Problem-Solving Approach

Presentation delivered by Lorraine Murray, Hannah Graham and Jane Eunson, with co-authors and fellow researchers Gill McIvor and Margaret Malloch, at the Scottish Government launch event, 'Problem Solving Approaches' of this research on 5th September 2018 in Edinburgh

Spindle-cell sarcoma of the popliteal fossa mimicking a benign vascular lesion

AbstractSpindle-cell sarcomas are a group of aggressive malignant soft-tissue tumors with diverse clinical presentations. While some of these tumors may represent de novo malignant transformation of benign entities, others may present with a long indolent course before their invasive nature is apparent. We report the case of a previously healthy 73-year-old female with spindle-cell sarcoma of the left popliteal fossa who initially presented with a painless mass of several months' duration. Magnetic resonance imaging (MRI) suggested a benign vascular lesion/venous angioma, but after the patient’s clinical course changed, repeat MRI 18 months later was consistent with an infiltrative soft-tissue malignancy/sarcoma. Excisional biopsy revealed a stage II spindle-cell sarcoma. The patient then underwent radiotherapy and subsequent above-the-knee amputation. Three years following the amputation, the patient is free of local tumor recurrence or metastatic disease