494 research outputs found
Using Preprints for Journal Clubs
N.G. thanks Sophien Kamoum for discussions on this topic, which helped shape his views.Peer reviewedPublisher PD
CO-OPERATING TO COMPETE IN HIGH VELOCITY GLOBAL MARKETS: THE STRATEGIC ROLE OF FLEXIBLE SUPPLY CHAIN ARCHITECTURES
Continued value creation is paramount for the survival of firms competing in today's high velocity global business environment. This paper presents a conceptual framework for understanding how firms can create and capture value within a highly volatile and uncertain business environment by exploiting both performance gaps and opportunity gaps through the development and use of flexible supply chain architectures. The choice of flexible organizational architecture allows for the continued reconfiguration of the independent modular components of the supply chain so as to achieve optimal leverage of both the firms core competencies as well as their collaborative partners complementary resources. The case of Cellars of Canterbury, a New Zealand based International wine marketing and distribution cooperative enterprise provides empirical support.Industrial Organization, International Relations/Trade,
CO-OPERATING TO COMPETE IN HIGH VELOCITY GLOBAL MARKETS: THE STRATEGIC ROLE OF FLEXIBLE SUPPLY CHAIN ARCHITECTURES
Continued value creation is paramount for the survival of firms competing in today's high velocity global business environment. This paper presents a conceptual framework for understanding how firms can create and capture value within a highly volatile and uncertain business environment by exploiting both performance gaps and opportunity gaps through the development and use of flexible supply chain architectures. The choice of flexible organizational architecture allows for the continued reconfiguration of the independent modular components of the supply chain so as to achieve optimal leverage of both the firms core competencies as well as their collaborative partners complementary resources. The case of "Cellars of Canterbury," a New Zealand based International wine marketing and distribution cooperative enterprise provides empirical support. Keywords: value creation, flexible supply chain architectures, leverage, core competencies.value creation, flexible supply chain architectures, leverage, core competencies., Industrial Organization, Marketing,
Proton damage comparison of an e2v technologies n-channel and p-channel CCD204
Comparisons have been made of the relative degradation of charge transfer efficiency in n-channel and p-channel CCDs subjected to proton irradiation. The comparison described in this paper was made using e2v technologies plc. CCD204 devices fabricated using the same mask set. The device performance was compared over a range of temperatures using the same experimental arrangement and technique to provide a like-for-like comparison. The parallel transfer using the p-channel CCD was then optimized using a trap pumping technique to identify the optimal operating conditions at 153 K
Fungal Genomics: Forensic Evidence of Sexual Activity
The genome sequence of the ‘asexual’ human pathogenic fungus Aspergillus fumigatus suggests it has the capability to undergo mating and meiosis. That this organism engages in clandestine sexual activity is also suggested by observations of two equally distributed complementary mating types in nature, the expression of mating type genes and evidence of recent genome recombination events
The importance of subclasses of chitin synthase enzymes with myosin-like domains for the fitness of fungi
Acknowledgements TG and CF are funded by FEDER funds through the Operational Programme Competitiveness Factors – COMPETE and national funds by FCT – Foundation for Science and Technology under the strategic project UID/NEU/04539/2013. C.F. is a recipient of a postdoctoral fellowship from FCT-Fundação para a Ciência e Tecnologia (SFRH/BPD/63733/2009). NG is funded by The Wellcome Trust (080088, 086827, 075470, 099215 & 097377), the FungiBrain Marie Curie Network and the Medical Research Council (UK).Peer reviewedPostprin
Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies
Date of Acceptance: 23/07/2015 We thank Gillian Milne for help with electron microscopy, Sophie M. Schäfer for pilot experiments, and Emilia Mellado for strains. All authors acknowledge financial support of Gilead Sciences through Ph.D. studentships for L.A.W. and K.K.L. We also acknowledge research grants from the Wellcome Trust (080088, 086827, 075470, 099215, and 097377) and the British Society for Antimicrobial Chemotherapy.Peer reviewedPublisher PD
Evolution of proton-induced defects in a cryogenically irradiated p-channel CCD
P-channel CCDs have been shown to display improved tolerance to radiation-induced charge transfer inefficiency (CTI) when compared to n-channel CCDs. This is attributed to the properties of the dominant charge-trapping defect species in p-channel silicon relative to the operating conditions of the CCD. However, precise knowledge of defect parameters is required in order to correct for any induced CTI. The method of single trap-pumping allows us to analyse the defect parameters to a degree of accuracy that cannot be achieved with other common defect analysis techniques such as deep-level transient spectroscopy (DLTS). We have analysed using this method the defect distribution in an e2v p-channel CCD204 irradiated with protons at cryogenic temperature (153K). The dominant charge trapping defects at these conditions have been identified as the donor level of the silicon divacancy and the carbon interstitial defect. The defect parameters are analysed both immediately post irradiation and following several subsequent room-temperature anneal phases. The evolution of the defect distribution over time and through each anneal phase provides insight into defect interactions and mobility post-irradiation. The results demonstrate the importance of cryogenic irradiation and annealing studies, with large variations seen in the defect distribution when compared to a device irradiated at room-temperature, which is the current standard procedure for radiation testing
Dissection of the Candida albicans class I chitin synthase promoters
We acknowledge financial support from the Biotechnology and Biological Sciences Research Council (10161), Medical Research Council (New Investigator Award to C.A.M.), the European Community FUNGALWALL and SIGNALPATH initiatives and the Wellcome Trust.Peer reviewedPublisher PD
Farm debt and financial viability
New Zealand Society of Farm Management Conference proceedings 1971.This bulletin has been produced by the Department of Farm Management and Rural Valuation of Lincoln College in association with the New Zealand Society of Farm Management. It consists of papers given at the Society of Farm Management section of the Annual Conference of the New Zealand Institute of Agriculture Science held at Lincoln College in August 1971. Deepening financial problems in the Sheep Industry have focussed attention on the need for a fuller understanding of the nature of these problems, and the policy measures needed to meet them. These papers make a contribution to this understanding
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