Development of Experimental Protocol for Visual Cognitive Function Evaluation in Children with Autism Spectrum Disorders

The article aims to present experimental protocol for investigation of visual cognitive function in children and adolescents with autism spectrum disorders. Description of experimental design is introduced by theoretical review of visual attention, perception and visual-motor control development in children with idiopathic autism and those with Fragile X mental retardation syndrome. Research method presented in the article is based on recent studies of visual cognitive function development under normal and pathological condition. The protocol includes three experimental paradigms: “antisaccade test”, “big/ figures”, and “photos test” performed by making use of eye tracking recording. This work was supported by grant RFBR 14-06-3128

On the mechanisms of the occurrence of autism spectrum disorders: a family case report

Currently, more than 1000 genes described in which mutations are observed in autism spectrum disorders. Neurobiological predictors have been found to presume these abnormalities in early postnatal ontogenesis. However, the mechanisms of the occurrence of these genetic abnormalities remain unclear. This is connected to the particular interest in the description of family cases in which ASD in combination with various genome features are observed. The data of a five-year comprehensive psychological and neurophysiological study of three siblings with various developmental features and genetic disorders inherited from the father are presented. The results revealed that all children showed an increase in altered chromosome regions inherited from their father. However, only in the case of an increase in repeats in chromosome 8, autism spectrum disorder was diagnosed in a child. Changes in the Y chromosome, apparently, are not associated with detected developmental disorders in two other children

Factors Influencing the Success Of Autism Spectrum Disorders Overcoming

No more than 10—20% of children with autism, as becoming adults can adapt to a relatively independent life. Despite many publications dedicated to autism, relatively little work has examined the output characteristics and pathomorphosis of psychic and cognitive disorders in people with autism spectrum disorders (ASD). Only few longitudinal studies allow us to represent what happens in later life with people who have ASD. For conducting effective correctional interventions overcomingwith children with ASD there is need to identify predictors of successful overcome of disorders. The basis for the study, conducted by a team of psychologists and neuroscientists, was the assumption that the information about the features of violations of basic neurobiological mechanisms in people with autism spectrum disorders should determine the tactics of assistance. Genetic, neurophysiological and psychological factors, causing more successful overcoming of these disorders in children are revealed