715 research outputs found
A hard-sphere model on generalized Bethe lattices: Statics
We analyze the phase diagram of a model of hard spheres of chemical radius
one, which is defined over a generalized Bethe lattice containing short loops.
We find a liquid, two different crystalline, a glassy and an unusual
crystalline glassy phase. Special attention is also paid to the close-packing
limit in the glassy phase. All analytical results are cross-checked by
numerical Monte-Carlo simulations.Comment: 24 pages, revised versio
Excitation of guided waves in layered structures with negative refraction
We study the electromagnetic beam reflection from layered structures that
include the so-called double-negative materials, also called left-handed
metamaterials. We predict that such structures can demonstrate a giant lateral
Goos-Hanchen shift of the scattered beam accompanied by splitting of the
reflected and transmitted beams due to the resonant excitation of surface waves
at the interfaces between the conventional and double-negative materials as
well as due to excitation of leaky modes in the layered structures. The beam
shift can be either positive or negative, depending on the type of the guided
waves excited by the incoming beam. We also perform finite-difference
time-domain simulations and confirm the major effects predicted analytically.Comment: 13 pqages, 10 figures. Also available at
http://www.opticsexpress.org/abstract.cfm?URI=OPEX-13-2-48
Unified theory for Goos-H\"{a}nchen and Imbert-Fedorov effects
A unified theory is advanced to describe both the lateral Goos-H\"{a}nchen
(GH) effect and the transverse Imbert-Fedorov (IF) effect, through representing
the vector angular spectrum of a 3-dimensional light beam in terms of a 2-form
angular spectrum consisting of its 2 orthogonal polarized components. From this
theory, the quantization characteristics of the GH and IF displacements are
obtained, and the Artmann formula for the GH displacement is derived. It is
found that the eigenstates of the GH displacement are the 2 orthogonal linear
polarizations in this 2-form representation, and the eigenstates of the IF
displacement are the 2 orthogonal circular polarizations. The theoretical
predictions are found to be in agreement with recent experimental results.Comment: 15 pages, 3 figure
Gyrotropic impact upon negatively refracting surfaces
Surface wave propagation at the interface between different types of gyrotropic materials and an isotropic negatively refracting medium, in which the relative permittivity and relative permeability are, simultaneously, negative is investigated. A general approach is taken that embraces both gyroelectric and gyromagnetic materials, permitting the possibility of operating in either the low GHz, THz or the optical frequency regimes. The classical transverse Voigt configuration is adopted and a complete analysis of non-reciprocal surface wave dispersion is presented. The impact of the surface polariton modes upon the reflection of both plane waves and beams is discussed in terms of resonances and an example of the influence upon the Goos–Hänchen shift is given
Fresnel filtering in lasing emission from scarred modes of wave-chaotic optical resonators
We study lasing emission from asymmetric resonant cavity (ARC) GaN
micro-lasers. By comparing far-field intensity patterns with images of the
micro-laser we find that the lasing modes are concentrated on three-bounce
unstable periodic ray orbits, i.e. the modes are scarred. The high-intensity
emission directions of these scarred modes are completely different from those
predicted by applying Snell's law to the ray orbit. This effect is due to the
process of ``Fresnel filtering'' which occurs when a beam of finite angular
spread is incident at the critical angle for total internal reflection.Comment: 4 pages, 3 figures (eps), RevTeX 3.1, submitted to Phys. Rev. Lett;
corrected a minor (transcription) erro
The contested and contingent outcomes of Thatcherism in the UK
The death of Margaret Thatcher in April 2013 sparked a range of discussions and debates about the significance of her period in office and the political project to which she gave her name: Thatcherism. This article argues that Thatcherism is best understood as a symbolically important part of the emergence of first-phase neoliberalism. It engages with contemporary debates about Thatcherism among Marxist commentators and suggests that several apparently divergent positions can help us now reach a more useful analysis of Thatcherism’s short- and long-term outcomes for British political economy. The outcomes identified include: an initial crisis in the neoliberal project in the UK; the transformation of the party political system to be reflective of the politics of neoliberalism, rather than its contestation; long-term attempts at the inculcation of the neoliberal individual; de-industrialisation and financial sector dependence; and a fractured and partially unconscious working class. In all long-term outcomes, the contribution of Thatcherism is best understood as partial and largely negative, in that it cleared the way for a longer-term and more constructive attempt to embed neoliberal political economy. The paper concludes by suggesting that this analysis can inform current debates on the left of British politics about how to oppose and challenge the imposition of neoliberal discipline today
Local Anisotropy of Fluids using Minkowski Tensors
Statistics of the free volume available to individual particles have
previously been studied for simple and complex fluids, granular matter,
amorphous solids, and structural glasses. Minkowski tensors provide a set of
shape measures that are based on strong mathematical theorems and easily
computed for polygonal and polyhedral bodies such as free volume cells (Voronoi
cells). They characterize the local structure beyond the two-point correlation
function and are suitable to define indices of
local anisotropy. Here, we analyze the statistics of Minkowski tensors for
configurations of simple liquid models, including the ideal gas (Poisson point
process), the hard disks and hard spheres ensemble, and the Lennard-Jones
fluid. We show that Minkowski tensors provide a robust characterization of
local anisotropy, which ranges from for vapor
phases to for ordered solids. We find that for fluids,
local anisotropy decreases monotonously with increasing free volume and
randomness of particle positions. Furthermore, the local anisotropy indices
are sensitive to structural transitions in these simple
fluids, as has been previously shown in granular systems for the transition
from loose to jammed bead packs
Bayesian D-Optimal Choice Designs for Mixtures
__Abstract__
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\nConsumer products and services can often be described as mixtures of ingredients. Examples are the mixture of ingredients in a cocktail and the mixture of different components of waiting time (e.g., in-vehicle and out-of-vehicle travel time) in a transportation setting. Choice experiments may help to determine how the respondents\' choice of a product or service is affected by the combination of ingredients. In such studies, individuals are confronted with sets of hypothetical products or services and they are asked to choose the most preferred product or service from each set.
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\nHowever, there are no studies on the optimal design of choice experiments involving mixtures. We propose a method for generating an optimal design for such choice experiments. To this end, we first introduce mixture models in the choice context and next present an algorithm to construct optimal experimental designs, assuming the multinomial logit model is used to analyze the choice data. To overcome the problem that the optimal designs depend on the unknown parameter values, we adopt a Bayesian D-optimal design approach. We also consider locally D-optimal designs and compare the performance of the resulting designs to those produced by a utility-neutral (UN) approach in which designs are based on the assumption that individuals are indifferent between all choice alternatives. We demonstrate that our designs are quite different and in general perform better than the UN designs
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Ribosomal Protein Mutations Induce Autophagy through S6 Kinase Inhibition of the Insulin Pathway
Mutations affecting the ribosome lead to several diseases known as ribosomopathies, with phenotypes that include growth defects, cytopenia, and bone marrow failure. Diamond-Blackfan anemia (DBA), for example, is a pure red cell aplasia linked to the mutation of ribosomal protein (RP) genes. Here we show the knock-down of the DBA-linked RPS19 gene induces the cellular self-digestion process of autophagy, a pathway critical for proper hematopoiesis. We also observe an increase of autophagy in cells derived from DBA patients, in CD34+ erythrocyte progenitor cells with RPS19 knock down, in the red blood cells of zebrafish embryos with RP-deficiency, and in cells from patients with Shwachman-Diamond syndrome (SDS). The loss of RPs in all these models results in a marked increase in S6 kinase phosphorylation that we find is triggered by an increase in reactive oxygen species (ROS). We show that this increase in S6 kinase phosphorylation inhibits the insulin pathway and AKT phosphorylation activity through a mechanism reminiscent of insulin resistance. While stimulating RP-deficient cells with insulin reduces autophagy, antioxidant treatment reduces S6 kinase phosphorylation, autophagy, and stabilization of the p53 tumor suppressor. Our data suggest that RP loss promotes the aberrant activation of both S6 kinase and p53 by increasing intracellular ROS levels. The deregulation of these signaling pathways is likely playing a major role in the pathophysiology of ribosomopathies
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