Extensions of Superscaling from Relativistic Mean Field Theory: the SuSAv2 Model

We present a systematic analysis of the quasielastic scaling functions computed within the Relativistic Mean Field (RMF) Theory and we propose an extension of the SuperScaling Approach (SuSA) model based on these results. The main aim of this work is to develop a realistic and accurate phenomenological model (SuSAv2), which incorporates the different RMF effects in the longitudinal and transverse nuclear responses, as well as in the isovector and isoscalar channels. This provides a complete set of reference scaling functions to describe in a consistent way both $(e, e')$ processes and the neutrino/antineutrino-nucleus reactions in the quasielastic region. A comparison of the model predictions with electron and neutrino scattering data is presented.Comment: 19 pages, 24 figure

Cancer stem cells and miRNA in the early diagnosis of colorectal carcinoma

Colorectal cancer represents the third cause of death for malignant tumor by incidence and mortality. Evidences suggest that tumor initiation, growth, invasion and cancer expansion are promoted by a small sub-population of tumor cells, called cancer stem cells (CSCs). On the other hand, MicroRNAs constitute a recently discovered class of small non-coding RNAs (about 22 nucletides) found in plants, animals and some viruses, that play key roles in the regulation of gene expression. An increasing number of studies have identified miRNAs as potential biomarkers for human cancer diagnosis, prognosis and therapeutic targets. However, a real translation of miRNA significance into the clinical practice deserves and needs further investigation. To this end, the aim of this work is to identify the expression of some specific microRNAs of this type of cancer, both in tissues and serum of cancer patients and in cancer stem cells, in order to allow early diagnosis. Therefore, some interesting microRNAs were chosen and their level was detected through amplification with real-time PCR method. A preliminary analysis of results shows that in some patients microRNA 21, 221, 18a, 210, 34a, 10b, 16 are overexpressed, while in others they manifest a lower expression. Instead, the microRNA 31 is always overexpressed. We think that this result is related to the clinical stage of the tumor, because patients with similar clinical stage show the same expression

Caracteres morfológicos e identificación de subfases durante la imbibición en semillas de alhelí (Matthiola incana): Germinación en alhelí

Objective: To describe morphologic traits and imbibition stages in seeds from three accessions of Matthiola incana. Design/methodology/approximation: Seeds were analysed from Nieve, Rosita and Uva genotipes, which correspond to the genus Matthiola and species incana. In the first assessment, weight and colour was determined in a thousand seeds. The area, perimeter, length (major axis), width, centric angle, elongation (length/width) and round degree were obtained by means of processing digital images. Analysis of variance was performed to the data followed by a multiple comparison of means by the Tukey procedure. For the imbibition test, fifty seeds of each genotype were immersed in water and evaluated every 24, 48, 72 and 164 hours in order to know the absorption dynamic and determine the time of the imbibition sub and phases.  Results: Physical description in Nieve seeds show a moderate orange colour and thousand seeds weight 0.218 g; Rosita seeds have a moderate orange yellowish colour and thousand seeds weight 0.1902 g; Uva seeds show a colour from greyish to dark brown with a weight of 0.1272 in thousand seeds. Nieve seeds show greater morphologic dimensions than Rosita and Uva seeds, but the three genotypes show a similar trait in the form type. During the imbibition test of each genotype follow a progressive rate until stage three, where the imbibition behaviour is synchronised with the radical protrude emergency to 164 h after the test was initiated.  Study limitations/implications: Seeds show a different size, therefore great samples are difficult to handle at the imbibition moment. Findings/conclusions: It is determined from the three accessions that seeds from Matthiola incana species have greater morphologic traits than other species from the same genus. Two phases were identified during the phase two, the first one was known as the moment of solute explosion and the second one was known as the recovery of lost solutes.Objetivo: Describir los atributos morfologicos y etapas de imbibición en semillas de tres accesiones de Matthiola incana. Diseño/metodología/aproximación: Fueron analizadas semillas de los genotipos Nieve, Rosita y Uva correspondientes genero Matthiola especie incana. En una primera evaluación se calculó el peso de mil semillas y, determino el color de las mismas. A través del procesamiento de imágenes digitales se determinó el área, perímetro, longitud (eje mayor), ancho, ángulo, elongación (longitud/ancho) y el grado de redondez; datos que fueron analizados en una prueba de comparación de medias por Tukey. En la imbibición se colocaron en remojo muestras de cincuenta semillas de cada genotipo y fueron evaluadas cada 24, 48, 72 y 164 h para conocer su dinámica de absorción y poder determinar el tiempo en que transcurren las sub y fases de imbibición. Resultados: La descripción física en semillas de Nieve muestra que son de color naranja moderado y el peso de mil semillas es de 0.218 g; en Rosita la semilla es de color amarillo anaranjado moderado y mil semillas pesan 0.1902; el color en semillas de Uva es grisáceo a café obscuro con un peso de 0.1272 g a mil semillas. En las dimensiones morfológicas Nieve muestra mayores dimensiones respecto a Rosita y Uva; pero entre los tres genotipos muestran semejanzas en el tipo de forma. Durante la prueba de imbibición cada genotipo sigue su ritmo hasta la fase tres, donde el comportamiento se sincroniza en la visión de la protuberancia radicular a las 164 h de iniciada la prueba. Limitaciones del estudio/implicaciones: Las semillas muestran diferente tamaño, por lo cual manipular muestras grandes se complica al momento de la imbibición. Hallazgos/conclusiones: De las tres accesiones se determina que semillas correspondientes a la especie incana, son de mayores atributos morfológicos que otras especies del mismo género. En la fase dos, se identificaron dos subfases, la primera reconocida como el momento de expulsión de solutos y la segunda como recuperación a los solutos perdidos

La discapacidad : aspectos educativos y sociales

Trabajo realizado a raíz del Congresos Internacional XXV años de la LISMIEstudia y compendia todos los cambios de la educación desde una perspectiva multidisciplinar y desde las diferencias epistemológicas de sus autores. Aborda el tratamiento de la discapacidad y de la educación especial desde una perspectiva multicultural y longitudinal, así como desde la diversidad geográfica y los distintos niveles de ejercicio profesional de sus autores. Estos son profesionales de la educación y atención a las personas con discapacidad, que ejercen en diversos niveles educativos: educación primaria, secundaria y universidad.AndalucíaBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín 5 -3 Planta; 28014 Madrid; Tel. +34917748000; [email protected]

Complete DNA sequence of yeast chromosome XI.

The complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome XI has been determined. In addition to a compact arrangement of potential protein coding sequences, the 666,448-base-pair sequence has revealed general chromosome patterns; in particular, alternating regional variations in average base composition correlate with variations in local gene density along the chromosome. Significant discrepancies with the previously published genetic map demonstrate the need for using independent physical mapping criteria.0Journal ArticleResearch Support, Non-U.S. Gov'tSCOPUS: ar.jinfo:eu-repo/semantics/publishe