1,423 research outputs found
De la arquitectura de información a la experiencia de usuario: Su interrelación en el desarrollo de software de la Universidad de las Ciencias Informáticas
A technical report on the application of activities and techniques of information architecture (AI) and UX user experience is presented based on the good practices obtained in the software development process of the University of Computer Science. For this, the most cited definitions of AI and their evolution towards the UX term were identified as a starting point to analyze the close relationship between these two concepts during software development. The work allows to recognize the protagonist role of the user in the result of their interaction with the product and the supplier or developer. It describes activities and techniques to obtain information and requirements in the stages of software development, which support good information architecture, focused on the user experience
The impact of organizational culture and leadership climate on organizational attractiveness and innovative behavior: a study of Norwegian hospital employees
In the domain of health services, little research has focused on how organizational culture, specifically internal market-oriented cultures (IMOCs), are associated with organizational climate resources, support for autonomy (SA), and whether and how IMOCs and SA are either individually or in combination related to employee perceptions of the attractiveness of the organization and their level of innovative behavior. These knowledge gaps in previous research motivated this study. A conceptual model was tested on a sample (N = 1008) of hospital employees. Partial least-squares structural equation modeling (PLS–SEM) was employed to test the conceptual models, using the SmartPLS 3 software. To test the mediator effect, a bootstrapping test was used to determine whether the direct and indirect effects were statistically significant, and when combining two tests, to determine the type of mediator effect. The results can be summarized as four key findings: i) organizational culture (referring to an IMOC) was positively and directly related to SA (β = 0.87) and organizational attractiveness (β = 0.45); ii) SA was positively and directly related to both organizational attractiveness (β = 0.22) and employee individual innovative behavior (β = 0.37); iii) The relationships between an IMOC, SA, and employee innovative behavior were all mediated through organizational attractiveness; and iv) SA mediated the relationship between the IMOC and organizational attractiveness as well as that between the IMOC and employee innovative behavior. Organizational culture, IMOC, organizational climate resources, and SA were highly correlated and necessary drivers of employee perceptions of organizational attractiveness and their innovative behavior. Managers of hospitals should consider IMOC and SA as two organizational resources that are potentially manageable and controllable. Consequently, managers should actively invest in these resources. Such investments will lead to resource capitalization that will improve both employee perceptions of organizational attractiveness as well as their innovative behavior. Keywords: Organizational culture, Organizational climate, Internal market-oriented culture, Support for autonomy, Organizational attractiveness, Innovative behavior, Hospital employeesThe impact of organizational culture and leadership climate on organizational attractiveness and innovative behavior: a study of Norwegian hospital employeespublishedVersio
De la arquitectura de información a la experiencia de usuario: Su interrelación en el desarrollo de software de la Universidad de las Ciencias Informáticas
A technical report on the application of activities and techniques of information architecture (AI) and UX user experience is presented based on the good practices obtained in the software development process of the University of Computer Science. For this, the most cited definitions of AI and their evolution towards the UX term were identified as a starting point to analyze the close relationship between these two concepts during software development. The work allows to recognize the protagonist role of the user in the result of their interaction with the product and the supplier or developer. It describes activities and techniques to obtain information and requirements in the stages of software development, which support good information architecture, focused on the user experience
Host-Nonspecific Iron Acquisition Systems and Virulence in the Zoonotic Serovar of Vibrio vulnificus
The zoonotic serovar of Vibrio vulnificus (known as biotype 2 serovar E) is the etiological agent of human and fish vibriosis. The aim of the present work was to discover the role of the vulnibactin- and hemin-dependent iron acquisition systems in the pathogenicity of this zoonotic serovar under the hypothesis that both are host-nonspecific virulence factors. To this end, we selected three genes for three outer membrane receptors (vuuA, a receptor for ferric vulnibactin, and hupA and hutR, two hemin receptors), obtained single and multiple mutants as well as complemented strains, and tested them in a series of in vitro and in vivo assays, using eels and mice as animal models. The overall results confirm that hupA and vuuA, but not hutR, are host-nonspecific virulence genes and suggest that a third undescribed host-specific plasmid-encoded system could also be used by the zoonotic serovar in fish. hupA and vuuA were expressed in the internal organs of the animals in the first 24 h of infection, suggesting that they may be needed to achieve the population size required to trigger fatal septicemia. vuuA and hupA were sequenced in strains representative of the genetic diversity of this species, and their phylogenies were reconstructed by multilocus sequence analysis of selected housekeeping and virulence genes as a reference. Given the overall results, we suggest that both genes might form part of the core genes essential not only for disease development but also for the survival of this species in its natural reservoir, the aquatic environment
Assessment of the IMERG Early-Run Precipitation Estimates over South American Country of Chile
Accurate rainfall measurement is a challenge, especially in regions with diverse climates and complex topography. Thus, knowledge of precipitation patterns requires observational networks with a very high spatial and temporal resolution, which is very difficult to construct in remote areas with complex geological features such as desert areas and mountains, particularly in countries with high topographical variability such as Chile. This study evaluated the performance of the near-real-time Integrated Multi-satellite Retrievals for GPM (IMERG) Early product throughout Chile, a country located in South America between 16°S–66°S latitude. The accuracy of the IMERG Early was assessed at different special and temporal scales from 2015 to 2020. Relative Bias (PBIAS), Mean Absolute Error (MAE), and Root-Mean-Squared Error (RMSE) were used to quantify the errors in the satellite estimates, while the Probability of Detection (POD), False Alarm Ratio (FAR), and Critical Success Index (CSI) were used to evaluate product detection accuracy. In addition, the consistency between the satellite estimates and the ground observations was assessed using the Correlation Coefficient (CC). The spatial results show that the IMERG Early had the best performance over the central zone, while the best temporal performance was detected for the yearly precipitation dataset. In addition, as latitude increases, so do errors. Also, the satellite product tends to slightly overestimate the precipitation throughout the country. The results of this study could contribute towards the improvement of the IMERG algorithms and open research opportunities in areas with high latitudes, such as Chile
The afterglow and kilonova of the short GRB 160821B
GRB 160821B is a short duration gamma-ray burst (GRB) detected and localized
by the Neil Gehrels Swift Observatory in the outskirts of a spiral galaxy at
z=0.1613, at a projected physical offset of 16 kpc from the galaxy's center. We
present X-ray, optical/nIR and radio observations of its counterpart and model
them with two distinct components of emission: a standard afterglow, arising
from the interaction of the relativistic jet with the surrounding medium, and a
kilonova, powered by the radioactive decay of the sub-relativistic ejecta.
Broadband modeling of the afterglow data reveals a weak reverse shock
propagating backward into the jet, and a likely jet-break at 3.5 d. This is
consistent with a structured jet seen slightly off-axis while expanding into a
low-density medium. Analysis of the kilonova properties suggests a rapid
evolution toward red colors, similar to AT2017gfo, and a low nIR luminosity,
possibly due to the presence of a long-lived neutron star. The global
properties of the environment, the inferred low mass (M_ej < 0.006 Msun) and
velocities (v > 0.05 c) of lanthanide-rich ejecta are consistent with a binary
neutron star merger progenitor.Comment: 14 pages, 6 figures, MNRAS, in press. Moderate revision, added Figure
5 and X-ray data to Table
Neuropilin 1 mediates epicardial activation and revascularization in the regenerating zebrafish heart
Unlike adult mammals, zebrafish can regenerate their heart. A key mechanism for regeneration is the activation of the epicardium, leading to the establishment of a supporting scaffold for new cardiomyocytes, angiogenesis and cytokine secretion. Neuropilins are co-receptors mediating signaling of kinase receptors for cytokines known to play critical roles in zebrafish heart regeneration. We investigated the role of neuropilins in response to cardiac injury and heart regeneration. All four neuropilin isoforms nrp1a, nrp1b, nrp2a and nrp2b were upregulated by the activated epicardium and a nrp1a knockout mutant showed a significant delay in heart regeneration and displayed persistent collagen deposition. The regenerating hearts of nrp1a mutants were less vascularized and epicardial-derived cell migration and re-expression of the developmental gene wt1b was impaired. Moreover, cryoinjury-induced activation and migration of epicardial cells in heart explants was reduced in nrp1a mutant. These results identify a key role for Nrp1 in zebrafish heart regeneration, mediated through epicardial activation, migration and revascularization
In tobacco BY-2 cells xyloglucan oligosaccharides alter the expression of genes involved in cell wall metabolism, signalling, stress responses, cell division and transcriptional control
Xyloglucan oligosaccharides (XGOs) are breakdown products of XGs, the most abundant hemicelluloses of the primary cell walls of non-Poalean species. Treatment of cell cultures or whole plants with XGOs results in accelerated cell elongation and cell division, changes in primary root growth, and a stimulation of defence responses. They may therefore act as signalling molecules regulating plant growth and development. Previous work suggests an interaction with auxins and effects on cell wall loosening, however their mode of action is not fully understood. The effect of an XGO extract from tamarind (Tamarindus indica) on global gene expression was therefore investigated in tobacco BY-2 cells using microarrays. Over 500 genes were differentially regulated with similar numbers and functional classes of genes up- and down-regulated, indicating a complex interaction with the cellular machinery. Up-regulation of a putative XG endotransglycosylase/hydrolase-related (XTH) gene supports the mechanism of XGO action through cell wall loosening. Differential expression of defence-related genes supports a role for XGOs as elicitors. Changes in the expression of genes related to mitotic control and differentiation also support previous work showing that XGOs are mitotic inducers. XGOs also affected expression of several receptor-like kinase genes and transcription factors. Hence, XGOs have significant effects on expression of genes related to cell wall metabolism, signalling, stress responses, cell division and transcriptional control
Modeling the Extragalactic Background Light from Stars and Dust
The extragalactic background light (EBL) from the far infrared through the
visible and extending into the ultraviolet is thought to be dominated by
starlight, either through direct emission or through absorption and reradiation
by dust. This is the most important energy range for absorbing \g-rays from
distant sources such as blazars and gamma-ray bursts and producing electron
positron pairs. In previous work we presented EBL models in the optical through
ultraviolet by consistently taking into account the star formation rate (SFR),
initial mass function (IMF) and dust extinction, and treating stars on the main
sequence as blackbodies. This technique is extended to include post-main
sequence stars and reprocessing of starlight by dust. In our simple model, the
total energy absorbed by dust is assumed to be re-emitted as three blackbodies
in the infrared, one at 40 K representing warm, large dust grains, one at 70 K
representing hot, small dust grains, and one at 450 K representing polycyclic
aromatic hydrocarbons. We find our best fit model combining the Hopkins and
Beacom SFR using the Cole et al. parameterization with the Baldry and
Glazebrook IMF agrees with available luminosity density data at a variety of
redshifts. Our resulting EBL energy density is quite close to the lower limits
from galaxy counts and in some cases below the lower limits, and agrees fairly
well with other recent EBL models shortward of about 5 m. Deabsorbing TeV
\g-ray spectra of various blazars with our EBL model gives results consistent
with simple shock acceleration theory. We also find that the universe should be
optically thin to \g-rays with energies less than 20 GeV.Comment: 13 pages, 10 figures, 3 tables, emulateapj. Version accepted by Ap
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