3 research outputs found

    Test immuchromatographique rapide pour le diagnostic sérologique de la tuberculose

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    The lCT tuberculosis is an in vitro immunodiagnostic test for the detection of antibodies to Mycobacterium tuberculosis in serum or plasma. This test targets 5 recombinant M tuberculosis proteins, including the 38 and 85 KDa antigens. We evaluated this test on 65 sera from patients with and without TB living in Liege. Patients and methods: This test was performed on two groups : The TB group included 31 patients condidered to have an active tuberculosis : pulmonary (26 cases) or extrapulmonary (5 cases). All of them had at least one sample with positive culture and received anti-tuberculous treatment. The identification of TB strains was performed with Accuprobe M tuberculosis complexe (Gen-Probe). The second group (control group) included 34 patients with the following characteristics: BCG negative nonexposed healthy (19), BCG positive or exposed healthy (2), non-TB respiratory disease (10), atypical TB (3). The identification of the atypical mycobacteria was determined according to the biochemical characteristics or by molecular biology. Results. The sensitivity is 38.7%, the specificity is 94%. The positive predictive value is 85.7% and the negative predictive value is 62,7%. Two false lCT positive results were found in the control group: both patients had a past infection with TB. Conclusion: This test is very easy and rapid to perform, has a good specificity but lacks sensitivity in low prevalence countries. A positive lCT allows same day diagnosis of Mycobacterium tuberculosis infection

    Point prevalence survey of antimicrobial use and healthcare-associated infections in Belgian acute care hospitals : results of the Global-PPS and ECDC-PPS 2017

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    Hospital antibiotic prescribing patterns in adult patients according to the WHO Access, Watch and Reserve classification (AWaRe) : results from a worldwide point prevalence survey in 69 countries

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