409 research outputs found
Polynomial Realization of and Fusion Rules at Exceptional Values of
Representations of the algebra are constructed in the space of
polynomials of real (complex) variable for . The spin addition rule
based on eigenvalues of Casimir operator is illustrated on few simplest cases
and conjecture for general case is formulated
Towards the noise reduction of piezoelectrical-driven synthetic jet actuators
This paper details an experimental investigation aimed at reducing the noise output of piezoelectrical-driven synthetic jet actuators without compromising peak jet velocity. Specifically, the study considers double-chamber ('back-to-back') actuators for anti-phase noise suppression and corrugated-lobed orifices as a method to enhance turbulent mixing of the jets to suppress jet noise. The study involved the design, manufacture and bench test of interchangeable actuator hardware. Hot-wire anemometry and microphone recordings were employed to acquire velocity and noise measurements respectively for each chamber configuration and orifice plate across a range of excitation frequencies and for a fixed input voltage. The data analysis indicated a 32% noise reduction (20 dBA) from operating a singlechamber, circular orifice SJA to a double-chamber, corrugated-lobed orifice SJA at the Helmholtz resonant frequency. Results also showed there was a small reduction in peak jet velocity of 7% (~3 m/s) between these two cases based on orifices of the same discharge area. Finally, the electrical-to-fluidic power conversion efficiency of the double-chamber actuator was found to be 15% across all orifice designs at the resonant frequency; approximately double the efficiency of a single-chamber actuator. This work has thus demonstrated feasible gains in noise reduction and power efficiency through synthetic jet actuator design
Higher Grading Conformal Affine Toda Teory and (Generalized) Sine-Gordon/Massive Thirring Duality
Some properties of the higher grading integrable generalizations of the
conformal affine Toda systems are studied. The fields associated to the
non-zero grade generators are Dirac spinors. The effective action is written in
terms of the Wess-Zumino-Novikov-Witten (WZNW) action associated to an affine
Lie algebra, and an off-critical theory is obtained as the result of the
spontaneous breakdown of the conformal symmetry. Moreover, the off-critical
theory presents a remarkable equivalence between the Noether and topological
currents of the model. Related to the off-critical model we define a real and
local Lagrangian provided some reality conditions are imposed on the fields of
the model. This real action model is expected to describe the soliton sector of
the original model, and turns out to be the master action from which we uncover
the weak-strong phases described by (generalized) massive Thirring and
sine-Gordon type models, respectively. The case of any (untwisted) affine Lie
algebra furnished with the principal gradation is studied in some detail.
The example of is presented explicitly.Comment: 28 pages, JHEP styl
Gene-based Interventions for Cancer Immunotherapy
Immunotherapy of cancer has deservedly gained much attention in the past few years and is likely to continue to advance and become a fundamental cancer treatment. While vaccines, chimeric antigen receptor (CAR) T cells and checkpoint blockade have received the lion’s share of the attention, an important direct role for gene transfer as an immunotherapy is emerging. For example, oncolytic viruses induce immunogenic cell death, thus liberating both antigens and the signals that are necessary for the activation of antigen-presenting cells, ensuring stimulation of an adaptive response. In another example, transfer of prodrug converting enzymes, such as the herpes simplex virus-thymidine kinase (HSV-tk) gene or the cytosine deaminase gene, has been shown to promote an immune response, thus functioning as immunotherapies. Alternatively, our own work involves the use of nonreplicating viral vectors for the simultaneous delivery of gene combinations that promote both cell death and an immune response. In fact, our gene transfer approach has been applied as a vaccine, immunotherapy or in situ gene therapy, resulting in immunogenic cell death and the induction of a protective immune response. Here, we highlight the development of these approaches both in terms of technical advances and clinical experience
Soliton Spectrum of Integrable Models with Local Symmetries
The soliton spectrum (massive and massless) of a family of integrable models
with local U(1) and U(1)\otimes U(1) symmetries is studied. These models
represent relevant integrable deformations of SL(2,R) \otimes U(1)^{n-1} - WZW
and SL(2,R) \otimes SL(2,R)\otimes U(1)^{n-2} - WZW models. Their massless
solitons appears as specific topological solutions of the U(1) (or U(1)\otimes
U(1)) - CFTs. The nonconformal analog of the GKO-coset formula is derived and
used in the construction of the composite massive solitons of the ungauged
integrable models.Comment: 44 pages, Latex, 1 eps fig, few misprints corrected. to appear in
JHE
Dislocation-induced spin tunneling in Mn-12 acetate
Comprehensive theory of quantum spin relaxation in Mn-12 acetate crystals is
developed, that takes into account imperfections of the crystal structure and
is based upon the generalization of the Landau-Zener effect for incoherent
tunneling from excited energy levels. It is shown that linear dislocations at
plausible concentrations provide the transverse anisotropy which is the main
source of tunneling in Mn-12. Local rotations of the easy axis due to
dislocations result in a transverse magnetic field generated by the field
applied along the c-axis of the crystal, which explains the presence of odd
tunneling resonances. Long-range deformations due to dislocations produce a
broad distribution of tunnel splittings. The theory predicts that at subkelvin
temperatures the relaxation curves for different tunneling resonances can be
scaled onto a single master curve. The magnetic relaxation in the thermally
activated regime follows the stretched-exponential law with the exponent
depending on the field, temperature, and concentration of defects.Comment: 17 pages, 14 figures, 1 table, submitted to PR
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