473 research outputs found

    Book Review: Women in Substance Abuse: Gender Transparency. Edited by Sally J. Stevens and Harry K. Wexler

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45668/1/11226_2004_Article_222762.pd

    Book review

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45263/1/10964_2005_Article_BF02089110.pd

    Determinants of early alcohol and drug use among young women in alcoholism treatment

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    Substance abuse experimentation may be one of several types of problem behaviors. Data from 99 Caucasian women interviewed in alcoholism treatment (19-29 years old) were used to test a developmental model of substance experimentation. Responders were classified into three groups based on their use prior to age 15: nonusers, users of alcohol only, and users of alcohol and other drugs. Family history of alcoholism was not related to childhood anxiety and impulse control problems. Childhood anxiety and impulse control problems predicted adolescent emotional and impulse control problems but did not differentiate early experimenters. Whereas adolescent emotional problems were not related to early experimentation, early drug and alcohol users were significantly more likely to have engaged in other impulsive behaviors (e.g., running away from home, trouble with school authorities) than were nonusers or users of alcohol only. Alcoholism prevention programs, therefore, would do well to target youth who exhibit acting-out behaviors as a high-risk group for early alcohol and drug use.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/31925/1/0000878.pd

    A Nuclear Reactor Simulator for Teachng Purposes

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    This is the full text of a paper presented at the Nuclear Engineering and Science Congress, Cleveland, Ohio, December 12-15, 1955.http://deepblue.lib.umich.edu/bitstream/2027.42/86097/1/MMPP Orr-Kerr-Gomberg, April 1956.PDF2

    A Nuclear Reactor Simulator for Teaching Purposes

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    For presentation at the Nuclear Engineering and Science Congress sponsored by Engineers Joint Council, December 12-16, 1955, at Cleveland Ohio.http://deepblue.lib.umich.edu/bitstream/2027.42/86101/1/MMPP Orr-Kerr-Gomberg Dec 1955.PDF2

    A Nuclear Reactor Simulator for Teaching Purposes

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    For presentation at the Nuclear Engineering and Science Congress sponsored by Engineers Joint Council, December 12-16, 1955, at Cleveland Ohio.http://deepblue.lib.umich.edu/bitstream/2027.42/86101/1/MMPP Orr-Kerr-Gomberg Dec 1955.PDF2

    Evidence for Anthropogenic Surface Loading as Trigger Mechanism of the 2008 Wenchuan Earthquake

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    Two and a half years prior to China's M7.9 Wenchuan earthquake of May 2008, at least 300 million metric tons of water accumulated with additional seasonal water level changes in the Minjiang River Valley at the eastern margin of the Longmen Shan. This article shows that static surface loading in the Zipingpu water reservoir induced Coulomb failure stresses on the nearby Beichuan thrust fault system at <17km depth. Triggering stresses exceeded levels of daily lunar and solar tides and perturbed a fault area measuring 416+/-96km^2. These stress perturbations, in turn, likely advanced the clock of the mainshock and directed the initial rupture propagation upward towards the reservoir on the "Coulomb-like" Beichuan fault with rate-and-state dependent frictional behavior. Static triggering perturbations produced up to 60 years (0.6%) of equivalent tectonic loading, and show strong correlations to the coseismic slip. Moreover, correlations between clock advancement and coseismic slip, observed during the mainshock beneath the reservoir, are strongest for a longer seismic cycle (10kyr) of M>7 earthquakes. Finally, the daily event rate of the micro-seismicity (M>0.5) correlates well with the static stress perturbations, indicating destabilization.Comment: 22 pages, 4 figures, 3 table

    Late gadolinium enhancement cardiovascular magnetic resonance predicts clinical worsening in patients with pulmonary hypertension

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    <p>Abstract</p> <p>Background</p> <p>Late gadolinium enhancement (LGE) occurs at the right ventricular (RV) insertion point (RVIP) in patients with pulmonary hypertension (PH) and has been shown to correlate with cardiovascular magnetic resonance (CMR) derived RV indices. However, the prognostic role of RVIP-LGE and other CMR-derived parameters of RV function are not well established. Our aim was to evaluate the predictive value of contrast-enhanced CMR in patients with PH.</p> <p>Methods</p> <p>RV size, ejection fraction (RVEF), and the presence of RVIP-LGE were determined in 58 patients with PH referred for CMR. All patients underwent right heart catheterization, exercise testing, and N-terminal pro-brain natriuretic peptide (NT-proBNP) evaluation; results of which were included in the final analysis if performed within 4 months of the CMR study. Patients were followed for the primary endpoint of time to clinical worsening (death, decompensated right ventricular heart failure, initiation of prostacyclin, or lung transplantation).</p> <p>Results</p> <p>Overall, 40/58 (69%) of patients had RVIP-LGE. Patients with RVIP- LGE had larger right ventricular volume index, lower RVEF, and higher mean pulmonary artery pressure (mPAP), all p < 0.05. During the follow-up period of 10.2 ± 6.3 months, 19 patients reached the primary endpoint. In a univariate analysis, RVIP-LGE was a predictor for adverse outcomes (p = 0.026). In a multivariate analysis, CMR-derived RVEF was an independent predictor of clinical worsening (p = 0.036) along with well-established prognostic parameters such as exercise capacity (p = 0.010) and mPAP (p = 0.001).</p> <p>Conclusions</p> <p>The presence of RVIP-LGE in patients with PH is a marker for more advanced disease and poor prognosis. In addition, this study reveals for the first time that CMR-derived RVEF is an independent non-invasive imaging predictor of adverse outcomes in this patient population.</p

    Magnetism in all-carbon nanostructures with negative gaussian curvature

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    The electronic and magnetic properties of an sp2 bonded all-carbon nanostructure, consisting of a nanotube junction structurally related to schwarzite, were investigated. The spin density functional theory was used during the investigation. The electronic structure of different tetrapods was calculated using the density functional theory within the local spin density approximation (LSDA). It was found that particular systems, which were related to schwarzite and contain no under-coordinated carbon atoms, carry a net magnetic moment in the ground state. The effect of edge termination on the net magnetic moment of the tetrapod was also studied.open13713
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