Technology and Competence Alignment to the Roadmap

Roadmaps serve as a useful graphical tool to integrate strategic objectives, technology-assessment, technology-road mapping and product road mapping against an axis of time. Much research has been done related to linking specific technologies with the product roadmap. It is equally important to understand how the sourcing of this technology can be done. This leads to the discussion of competence development to meet the technology gap. the paper describes the alignment of this technology and competence with the overall roadmap. © 2008 IEEE

System services and architecture of the TMI satellite mobile data system

The North American Mobile Satellite Service (MSS) system being developed by AMSC/TMI and scheduled to go into service in early 1995 will include the provision for real time packet switched services (mobile data service - MDS) and circuit switched services (mobile telephony service - MTS). These services will utilize geostationary satellites which provide access to mobile terminals (MT's) through L-band beams. The MDS system utilizes a star topology with a centralized data hub (DH) and will support a large number of mobile terminals. The DH, which accesses the satellite via a single Ku band beam, is responsible for satellite resource management, for providing mobile users with access to public and private data networks, and for comprehensive network management of the system. This paper describes the various MDS services available for the users, the ground segment elements involved in the provisioning of these services, and a summary description of the channel types, protocol architecture, and network management capabilities provided within the system

Pyrexia of unknown origin: a rare presentation of primary ovarian lymphoma

It is very rare to have a lymphomatous involvement of ovary. Malignant lymphoma of ovary is a well-known late manifestation of disseminated nodal disease. Primary ovarian lymphoma with ovarian mass as an initial manifestation is a rare entity and may have varied presentations which can cause confusion to the physician and cause delay in diagnosis. Study presents a case of non-Hodgkin’s lymphoma where the initial presentation was fever with weight loss, and was evaluated as pyrexia of unknown origin. When no other cause of fever was identified PET-CT was done showing metabolically active uterine mass with no lymphadenopathy. Exploratory laparotomy was planned followed by hysterectomy with bilateral salpingo ophorectomy with omentectomy. Ovarian malignancy was detected intraoperatively, which was diagnosed as diffuse large B cell lymphoma, NHL double expresser phenotype on histopathology and IHC. Patient was started on chemotherapy and is doing fine

MANGO STARCH: ITS USE AND FUTURE PROSPECTS

Mango (Mangifera indica L.) is tropical fruit with high nutritional value. The aim of present work was to isolate the starch from black variety of mango and evaluate the physicochemical as well as functional properties. Starch is widely used in the food and pharmaceutical industries for various applications. These industries depend on crops that are also the traditional sources of food resulting high demands with consequence economic implications. The results showed that the moisture content (14.93%) was higher while ash content (0.12%) was low. Amylose content was 35.06%. It was observed that the onset gelatinization temperature of the starch ranged from 50°C whereas, the conclusion gelatinization temperature was from 91-92.5°C. The starch show adequate properties and could be alternative source for the production of industrial products that may require starch.Â

Microwave Spectroscopy

Contains reports on five research projects.United States Army Signal Corps (Contract DA36-039-sc-74895

Evidence of co-infection of chikungunya and densonucleosis viruses in C6/36 cell lines and laboratory infected Aedes aegypti (L.) mosquitoes

<p>Abstract</p> <p>Background</p> <p>Densonucleosis viruses are the etiological agents of insect's disease. We have reported the isolation of densovirus from India and its distribution among the natural populations of <it>Aedes aegypti </it>mosquitoes across the country. Since densonucleosis virus persistently infects mosquito populations, and is demonstrated to negatively affect multiplication of dengue virus in <it>Aedes albopictus</it>, it would be interesting to study if this virus has a role in determining the susceptibility of the vector mosquito <it>Ae. aegypti </it>to chikugunya virus.</p> <p>Methods</p> <p>Mosquito cell lines and adult <it>Ae. aegypti </it>mosquitoes infected with densovirus were superinfected with Chikungunya virus and both the viruses were quantitated by determining their genomic copy number by real time amplification. Comparison was made between the log of genomic copy numbers of the viruses in the presence and absence of each other.</p> <p>Results</p> <p>The log of copy number of the viruses did not vary due to co-infection. Even though the RNA copy number of chikungunya virus increased over the period of time, no change was observed in the RNA copy number between the control and the co-infected group on any given day. Similarly, DNA copy number of densovirus also remained unchanged between the control and the co-infected groups.</p> <p>Conclusion</p> <p>Chikungunya virus neither stimulates the replication of densovirus nor is its own replication suppressed due to co-infection. <it>Ae. aegypti </it>mosquitoes with densovirus infection were as susceptible to infection by chikungunya virus as the uninfected mosquitoes.</p

Polarization state of atmospheric Cerenkov events-guidance from simulation studies

We have been systematically carrying out experimental and simulation studies of the polarization properties of atmospheric ˇCerenkov events (ACE) produced by very high energy (VHE) and ultrahigh energy (UHE) γ-ray and cosmic ray proton progenitors. We present here an interim report on the work, based on some recent simulation investigations

A Peptide from the Beta-strand Region of CD2 Protein that Inhibits Cell Adhesion and Suppresses Arthritis in a Mouse Model

This is the peer reviewed version of the following article: Satyanarayanajois, S. D., Büyüktimkin, B., Gokhale, A., Ronald, S., Siahaan, T. J. and Latendresse, J. R. (2010), A Peptide from the Beta-strand Region of CD2 Protein that Inhibits Cell Adhesion and Suppresses Arthritis in a Mouse Model. Chemical Biology & Drug Design, 76: 234–244. doi:10.1111/j.1747-0285.2010.01001.x, which has been published in final form at http://doi.org/10.1111/j.1747-0285.2010.01001.x. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.Cell adhesion molecules play a central role at every step of the immune response. The function of leukocytes can be regulated by modulating adhesion interactions between cell adhesion molecules to develop therapeutic agents against autoimmune diseases. Among the different cell adhesion molecules that participate in the immunological response, CD2 and its ligand CD58 (LFA-3) are two of the best-characterized adhesion molecules mediating the immune response. To modulate the cell adhesion interaction, peptides were designed from the discontinuous epitopes of the β-strand region of CD2 protein. The two strands were linked by a peptide bond. β-Strands in the peptides were nucleated by inserting a β-sheet-inducing Pro-Gly sequence with key amino acid sequences from CD2 protein that binds to CD58. Using a fluorescence assay, peptides that exhibited potential inhibitory activity in cell adhesion were evaluated for their ability to bind to CD58 protein. A model for peptide binding to CD58 protein was proposed based on docking studies. Administration of one of the peptides, P3 in collagen-induced arthritis (CIA) in the mouse model, indicated that peptide P3 was able to suppress rheumatoid arthritis in mice