The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

Abstract: Transformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, consortia, and the biomedical research community at large towards the shared vision of a comprehensive, accessible three-dimensional molecular and cellular atlas of the human body, in health and under various disease conditions

The stigma turbine:A theoretical framework for conceptualizing and contextualizing marketplace stigma

Stigmas, or discredited personal attributes, emanate from social perceptions of physical characteristics, aspects of character, and “tribal” associations (e.g., race; Goffman 1963). Extant research emphasizes the perspective of the stigma target, with some scholars exploring how social institutions shape stigma. Yet the ways stakeholders within the socio-commercial sphere create, perpetuate, or resist stigma remain overlooked. We introduce and define marketplace stigma as the labeling, stereotyping, and devaluation by and of commercial stakeholders (consumers, companies and their employees, stockholders, institutions) and their offerings (products, services, experiences). We offer the Stigma Turbine (ST) as a unifying conceptual framework that locates marketplace stigma within the broader sociocultural context, and illuminates its relationship to forces that exacerbate or blunt stigma. In unpacking the ST, we reveal the critical role market stakeholders can play in (de)stigmatization, explore implications for marketing practice and public policy, and offer a research agenda to further our understanding of marketplace stigma and stakeholder welfare

Modelling human choices: MADeM and decision‑making

Research supported by FAPESP 2015/50122-0 and DFG-GRTK 1740/2. RP and AR are also part of the Research, Innovation and Dissemination Center for Neuromathematics FAPESP grant (2013/07699-0). RP is supported by a FAPESP scholarship (2013/25667-8). ACR is partially supported by a CNPq fellowship (grant 306251/2014-0)

A comparative analysis of the accuracy of different direct impression techniques for multiple implants

Background: The aim of this study was to compare the accuracy of different direct implant impression techniques for edentulous arches with multiple implants. Methods: Five experimental groups (n = 5) were assembled. Experimental models were created by a direct splinted technique (EG2 to EG5) and a non-splinted technique (EG1). In EG2 and EG3 synOcta impression copings were splinted with an acrylic resin bar, and in EG4 and EG5 with a light-curing composite resin bar. In EG3 and EG5 the resin bars were sectioned, while the other experimental groups were not. Three-dimensional discrepancies were measured by a computerized coordinate measuring machine. Distortion values among the groups were analysed using one-way repeated measures ANOVA. The post hoc Tukeys test was then performed for multiple comparisons. Results: The highest accuracy was obtained in EG2 (mean deviation: 12.70 mu m). The acrylic bars demonstrated less deviation (12.70 mu m and 22.71 mu m) from the master model than the light-curing composite resin groups and the non-splinted group (41.09 mu m). The post hoc Tukeys test showed no significant difference among the groups when the effect of splint design on accuracy was investigated. Conclusions: For situations where impressions of multiple implants are to be made, splinting impression copings with acrylic resin demonstrate superior results than the non-splinted technique and splinting with light-curing composite

Bulletin (United States. Bureau of Mines)

From Introduction: "This compilation is part of the Bureau of Mines continuing effort to provide information for use as guidelines in mineral technology advancement, pollution control, and energy economy.

United States Bureau of Mines Information Circular 8853

Report issued by the U.S. Bureau of Mines discussing a workshop held on the techniques for measurement of thermodynamic properties. As stated in the abstract, "this information circular comprises the proceedings of the workshop and includes the texts of papers presented and discussion by attendees" (p. 1). This report includes tables, illustrations, and photographs

Entropy in Born-Infeld gravity

There is a class of higher derivative gravity theories that are in some sense natural extensions of cosmological Einstein's gravity with a unique maximally symmetric classical vacuum and only a massless spin-2 excitation about the vacuum and no other perturbative modes. These theories are of the Born-Infeld determinant form. We show that the macroscopic dynamical entropy as defined by Wald for bifurcate Killing horizons in these theories are equivalent to the geometric Bekenstein-Hawking entropy (or more properly Gibbons-Hawking entropy for the case of de Sitter spacetime) but given with an effective gravitational constant which encodes all the information about the background spacetime and the underlying theory. We also show that the higher curvature terms increase the entropy. We carry out the computations in generic n dimensions including the particularly interesting limits of three, four and infinite number of dimensions. We also give a preliminary discussion about the black hole entropy in generic dimensions for the Born-Infeld theories