10 research outputs found
Trabecular bone score (TBS) as a noninvasive and complementary tool for clinical diagnosis of bone structure in endocrine disorders
Trabecular bone score (TBS) index has recently been obtained as a result of textural greyscale analysis of DXA images. Because it enables the assessment of bone microarchitectural texture, TBS may be useful in evaluating bone quality. This study explores the current knowledge of the use of TBS in patients with endocrine disorders with co-occurring bone structure changes. Currently, the clinical importance TBS was verified in terms of disorders of the growth hormone/insulin-like growth factor 1 (GH/IGF-I) axis, glucocorticoid excess, thyroid and parathyroid disease, as well as in diabetes mellitus type 1 and 2.It has been clarified that patients suffering from various endocrinopathies are a group in which TBS should be used routinely because it correlates with clinical factors and may improve patient management in various endocrine disorders.
The influence of physiotherapy on blood pressure in children and adolescents with respiratory tract diseases
Background. Arterial hypertension is an essential, often underestimated medical problem among school youth. Maintaining a low blood pressure (BP) in children should be an important point of pediatric preventive healthcare.
Objectives . In our study, we considered the influence of physiotherapy on the blood pressure level in a group of 233 children aged from 8 to 15 years taking part in a rehabilitation camp for children in the Szklarska Poreba mountain resort (95 children in 2014 and 138 children in 2015).
Material and methods. The children selected for the study suffered from asthma or recurrent respiratory infections. Measurements were made before and after physiotherapy. During the camp, the children were examined two times in 2014 and three times in 2015. The database created contained 1,208 scores of systolic and diastolic BP. The control group consisted of 50 children whose BP was measured in the same hours, but during the weekend, which was free of physiotherapy. Moreover, the values of heart rate (HR ) during
the first measurement were recorded, both in 2014 and 2015.
Results. Systolic BP after physiotherapy was significantly lower than before. This result was achieved in every five measuring sessions. In the control group, BP measured in the afternoon was higher than in the morning. The values of HR were not significantly different. The values of BP before and after physiotherapy between children treated with inhaled glucocorticoids and treated without glucocorticoid were not statistically significant.
Conclusions . Our studies showed that morning exercise can significantly reduce blood pressure in children throughout the day, even in those who were treated with inhaled glucocorticoids
Assessment of the prevalence of taking psychoactive substances in secondary school students from the Silesia region
Background: The aim of the study was to scrutinize
the scale of a current problem of psychoactive substances
taking by adolescents aged 13–16, including the level of
their knowledge of that subject. The results obtained can
help to create an educational program targeted at decreasing
the number of students using drugs. Material and
methods: The study was performed on a group of 197
secondary school students in 2013 with the use of selfdeveloped
query based on ESPAD (The European School
Survey Project on Alcohol and Other Drugs) questionnaire.
Results: 25% of the students showed their curiosity
in trying some psychoactive substances, if those were
legal. 19% declared that they already have had a contact
with drugs. Teenagers are worried about the possible reaction
of their parents and legal consequences of the use
of psychoactive substances. At least every tenth of the respondents
have had an opportunity to try marihuana.
Conclusions: Despite the low average age the group of
respondents has had contact with psychoactive substances.
Every third person has been offered psychoactive
substances. At least 40% of teenagers know about the
possible ways where to take the drugs from. The outcome
of the study is quite alarming because it shows a considerable
interest in common drugs, as well as in some OTC
medicaments
Serum Concentration of IL-5 Receptor (IL-5R) and Associations with Disease Severity in Patients with Chronic Spontaneous Urticaria (CSU) and Atopic Dermatitis (AD)
The immunological pathogenesis of atopic dermatitis (AD) and chronic spontaneous urticaria (CSU) has not been fully elucidated yet. The aim of our research was to assess the serum concentration of interleukin-5 receptor (IL-5R) in relation to the disease activity and pruritus intensity in adult patients with AD and CSU. This pilot study included 45 participants (15 patients with AD, 15 patients with CSU, and 15 healthy controls). Blood samples were taken to examine the serum levels of IL-5R using the enzyme-linked immunosorbent assay (ELISA) test. The Scoring Atopic Dermatitis (SCORAD) index, the Urticaria Activity Score (UAS7), and the Visual Analogue Scale (VAS) were used to assess the disease activity and the pruritus intensity, respectively. Obtained results revealed that the IL-5R concentration was significantly higher in patients with CSU than in patients with AD and in the controls (p = 0.038). There was a positive correlation between the IL-5R level and the SCORAD index in patients with AD (r = −0.9, p = 0.047), which was not found for the CSU activity by UAS7 and with the pruritus severity by VAS in both examined groups of patients. Our findings underscore higher serum levels of IL-5R among CSU and AD patients, which may highlight its functional role in the pathogenesis of these diseases. In contrast, IL-5R might not be fully useful in reflecting the severity of symptoms. Although our results are promising, this study should be conducted on a larger cohort of patients
The influence of physiotherapy on blood pressure in children and adolescents with respiratory tract diseases
Background. Arterial hypertension is an essential, often underestimated medical problem among school youth. Maintaining a low blood pressure (BP) in children should be an important point of pediatric preventive healthcare.
Objectives . In our study, we considered the influence of physiotherapy on the blood pressure level in a group of 233 children aged from 8 to 15 years taking part in a rehabilitation camp for children in the Szklarska Poreba mountain resort (95 children in 2014 and 138 children in 2015).
Material and methods. The children selected for the study suffered from asthma or recurrent respiratory infections. Measurements were made before and after physiotherapy. During the camp, the children were examined two times in 2014 and three times in 2015. The database created contained 1,208 scores of systolic and diastolic BP. The control group consisted of 50 children whose BP was measured in the same hours, but during the weekend, which was free of physiotherapy. Moreover, the values of heart rate (HR ) during
the first measurement were recorded, both in 2014 and 2015.
Results. Systolic BP after physiotherapy was significantly lower than before. This result was achieved in every five measuring sessions. In the control group, BP measured in the afternoon was higher than in the morning. The values of HR were not significantly different. The values of BP before and after physiotherapy between children treated with inhaled glucocorticoids and treated without glucocorticoid were not statistically significant.
Conclusions . Our studies showed that morning exercise can significantly reduce blood pressure in children throughout the day, even in those who were treated with inhaled glucocorticoids
The Analysis of the Exhaled Nitric Oxide in a Group of Patients with Asthma, Aged 3-18
The aim of this study was to analyse the results of exhaled nitric oxide examination in a group of patients with hyper-responsive-ness. The study was performed on a group of 297 children who underwent spirometry, examination of exhaled nitric oxide, skin prick test and stress probe in years 2010-2012 in Pulmonology and Allergy Centre in Karpacz. Mean age of patients was 11.86. Patients were divided into four groups: with diagnosed asthma, with bronchial hyper-responsiveness (BHR), with described asthma without BHR and a group with BHR without diagnosed asthma. The results of the study confirmed the presence of high-er amount of exhaled nitric oxide in patients with asthma and bronchial hyper-responsiveness. The elevation of NO concen-tration correlated with age; there was no significant difference between sexes
Analiza porównawcza ilości wydychanego tlenku węgla jako wskaźnika palenia tytoniu wśród wybranych studentów uczelni we Wrocławiu
Background: The aim of this study is to compare the
amount of exhaled carbon monoxide which can be an
indicator of the phenomenon of tobacco smoking among
youngsters in a group of students of Wroclaw’s universities.
Materials and methods: The study was performed
on 347 students living in dormitories of four Wroclaw
universities: Wroclaw Medical University, University of
Wroclaw, University of Physical Education and Technical
University. Every tested student underwent a measurement
of quantities of exhaled carbon monoxide by a Micro
Medical Smoke Check device. Every participant took
part in an anonymous survey, which was divided into
three parts (for smokers/non-smokers/ex-smokers) and
included exposure to tobacco smoke, length of time smoking
etc. Results: No difference in the amount of exhaled
CO between students of particular universities was observed.
The Smoke Check measurements are higher in actively
smoking students compared to nonsmokers. The
results are higher in students declaring passive smoking
compared with those not exposed to tobacco smoke at
all. No difference in level of CO between genders and particular
age groups was observed. Conclusions: Despite
higher health awareness, students of the Medical University
and University of Physical Education reach for cigarettes
as often as the other tested students. Male students
smoke as often as female students and CO result was not
dependent on age.Wstęp: Celem pracy jest porównanie ilości wydychanego
tlenku węgla przez studentów wybranych uniwersytetów
we Wrocławiu, jako wskaźnika pomocnego
przy ocenie zjawiska palenia tytoniu u młodzieży studiującej.
Materiały i metody: Badanie przeprowadzono
wśród 347 studentów zamieszkujących domy studenckie
czterech wrocławskich uczelni: Uniwersytetu Medycznego,
Uniwersytetu Wrocławskiego, Akademii Wychowania
Fizycznego i Politechniki Wrocławskiej. Zbadano
ilość wydalanego tlenku węgla z użyciem urządzenia
Micro Medical Smoke Check. Każdy uczestnik wziął
udział z ankiecie dotyczącej jego kontaktu z dymem tytoniowym. Wyniki: Nie zaobserwowano różnić w ilości
wydychanego CO między studentami różnych uczelni.
Wyniki były najwyższe w grupie osób aktywnie palących.
Grupa osób biernie palących wydalała więcej CO
niż osoby nie deklarujące narażenia na dym tytoniowy.
Nie zauważono różnic między grupą mężczyzn i kobiet,
jak i między różnymi grupami wiekowymi. Wnioski:
Pomimo większej świadomości zdrowotnej, studenci
Uniwersytetu Medycznego i Akademii Wychowania Fizycznego
sięgają po papierosa częściej, niż pozostali.
Kobiety okazały się palić równie często, jak mężczyźni.
Nie zaobserwowano różnic w ilości wydalanego CO
między płciami