Ecological studies of Bisheh-palan Wetland (Broojerd)

Bisheh-Dalan wetland is located in southern of Broojerd city near the Tireh River with 914 hectares area.This survey was done in 2002-2003.Water temperature variation between 8 at 23/5 °C, the quantity pH between 6.5-7.4, Ec between 362-443 μm/cm, minimum-dissolved oxygen 5/5 mg/l in Bisheh-Dalan area. The phytoplankton comprised 4 families and 15 genus include (Microcystis Gloeotrehia Gloeocapsa, Merismopedia Ceratium, Glenodinium, Gymnodinium, Peridinium Closterium, Stauratrum, Treubaria, Cymbella, Cyclotella, Nitzchia, Navieula), the zooplanktons had 3 families and 10 genus, consist (Stmocephalus, Shnucephalus, Diaphanasoma, Simocephalus, Daphnia, Eueyclops, Attheylla, Cyclops, Trinema, Aeanthoeyclops) and the benthos have been had 10 orders and 15 families with names (Ecdyonuridae, Caenidae, Baetidae, Chiranomidae, Calicidae, Dytiscidae, Limmaeidae, Planorbiidae, Glossosomatidae , Tubificidae, Erpobdellidae, Planariidae, Gammaridae) in Bisheh-Dalan area. The fishes of Bisheh-Dalan wetland composed 2 family with names Cyprinidae and poeciliidae with 7 genus and 8 species. Maximum number of fishes located to Capoeta with 2 Species

Evaluating the effect of lycopene on telomerase activity in the human leukemia cell line K562

Background: Telomerase has been proposed as a novel and potentially selective target in cancer therapy. Many plant-derived products can induce apoptosis via telomerase inhibition. Lycopene (a carotenoid pigment) has been found to exhibit the various biological effects on different types of cancer cells, but its effect on telomerase activity has not been investigated. Therefore, this study aimed to examine the apoptosis-inducing effect of lycopene on human leukemia cell line K562, with particular emphasis on its effect on telomerase inhibition. Materials and Methods: Anti-proliferative effect of lycopene at different doses (0-20µm) and time intervals (24-72 h) on K562 cells was evaluated using the 3-(4, 5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. To measure apoptosis, the Hoechst 33342 staining method and flow cytometry were used. The telomerase activity was determined using the telomeric repeat amplification protocol (TRAP) and ELISA assay.Results: The treatment of the K562 cells with lycopene dose-dependently resulted in a significant inhibition of cell growth and telomerase activity compared to the untreated cells. Furthermore, a positive correlation was found between telomerase inhibition and the induction of apoptosis in lycopene-treated K562 cells. Conclusion: The results of this study suggest a novel mechanism in the anti-cancer activity of lycopene in human leukemia K562 cells and may provide a basis for the future development of anti-telomerase agents

The Effect of Massage Therapy by Sunflower Oil on Neonates for Length of Hospital Stay from the Hospital

Introduction: Infants are the most sensitive and injury of people in society that will make the feature of our country so they are needed special attention to take care of their physical &mental health. According to many studies one of the intervention for decrease of length of stay (LOS) in Intensive Care Unit (NICU) is massage therapy by oil because of rapidly recovery & early discharge. The aim of this study was to the effect of massage on neonates in Nicu ward for decreasing of LOS. Materials & Methods:. This one- blinded clinical trial was conducted on 44 infants who were born within 30-37weeks gestational age with 1000-2500gr in Nicu of Arash & Shariati hospitals. The infants were assigned randomly into two group of sunflower oil massage &without massage. The massage is done one hour after milk when the infants were stable (heart rate-respiratory rate and color of their skin become control). Each massage was 15minute 3 times in every 2 hours in the afternoon for 5 days. Observation was tools of collecting data by researcher which done before &after every intervention by respiratory heart rate monitoring & pulse oximetry. Data were analyzed using the repeated measure ANOVA. Results: Within 5 days of following increasing pattern of infant weight in study group was significant (P=0.001) and comparison growth head circumference in 2 groups was not significant (P=0.01) about LOS variable within 5days massage was significant (P=0.04). Conclusion: Fortunately there were statistical significant difference between the infants weight and decreasing length of hospitalization in 2 groups , but difference between head circumference between 2 group was not significant

The Implementation of Pain Management and Assessment in Neonatal Intensive Care Units of Teaching Hospitals Affiliated to Tehran University of Medical Sciences

BACKGROUND AND OBJECTIVE: Neonatal pain causes changes in the structure and function of brain in addition to acute physiologic symptoms and is followed by delayed development of infants. This study aims to determine the implementation of pain management and assessment in neonatal intensive care units. METHODS: This cross-sectional study was conducted among 138 nurses working in neonatal intensive care units through census. The data were collected using researcher – made questionnaire including two parts: pain management and assessment and demographic information. The minimum and maximum scores were 0 and 552, respectively, shown in the form of percentage. FINDINGS: At a response rate of 80.23%, the mean age of participants was 31.76±5.41 years and the mean experience of nurses working in a neonatal intensive care unit was 4.36 ± 3.58 years. The cases of implementation of pain management and assessment were as follows: care management for pain reduction (72.8%), allow parents to relieve pain (68.5%), swaddling (66.7%), pain assessment while implementing therapeutic and caring measures (62.9%), the use of sucrose solution (61.6%), teaching parents about observing pain symptoms in the infant’s face (58.7%), recording infant’s pain behaviors and the method for relieving the pain (52.4%), pain assessment at least every 4 hours (52.2%) and the use of valid tools for pain assessment (36.8%). CONCLUSION: According to the results of this study, pain management and assessment was implemented in more than half of the cases

A new interval-valued approximation of interval-valued fuzzy numbers

In this paper, we proposed a new interval-valued approximation of interval-valued fuzzy numbers, which is the best one with respect to a certain measure of distance between interval-valued fuzzy numbers. Also, a set of criteria for interval-valued approximation operators is suggested

T-Helper Cytokine Patterns and Related Antibodies in Patients with Gestational Diabetes Mellitus

Background: Diabetes mellitus (DM) is a group of metabolic disorders such as DM I, DM II, secondary causes of DM and gestational diabetes mellitus characterized by hyperglycemic phonotype. The etiology of gestational diabetes mellitus is unknown. Recent studies address the chronic activity of immune system against infections (not autoimmunity) as an important cause of gestational diabetes mellitus. This study aimed to compare T-helper cells 1 and 2 cytokines and associated antibodies in patients with gestational diabetes mellitus and normal pregnant women. Methods: This cross-sectional study was performed on 45 female patients with GDM and 45 healthy pregnant women in Bandar Abbas, Iran, from 2008- 2009. The exclusion criteria were presence of any infectious diseases or autoimmune disorders such as SLE or RA. Present and past medical histories were taken from the participants thorough physical examination. Blood samples (10 mL) were drawn and sent to laboratory for measuring serum IgE, IgG1, IgG2, IgG3, IgG4, interleukin-10 (IL-10), interleukin-12 (IL-12), transforming growth factor-beta (TGF1), and interferon-gamma (IFN) measurements. T-test and Kolmogorov-Smirnov test were used for data analysis. Results: The mean age of the patients with GDM and healthy pregnant women was 32.5 and 27.9 yrs, respectively. T-helper 1 and 2 associated antibodies and cytokines had no significant differences between the case and control groups. Conclusion: The changes in T-helper 1 and 2 associated antibodies and cytokines are not associated with gestational diabetes mellitus and could not be considered as a predictor for gestational diabetes mellitus

T-helper cytokine patterns and related antibodies in patients with gestational diabetes mellitus

Background: Diabetes mellitus (DM) is a group of metabolic disorders such as DM I, DM II, secondary causes of DM and gestational diabetes mellitus characterized by hyperglycemic phonotype. The etiology of gestational diabetes mellitus is unknown. Recent studies address the chronic activity of immune system against infections (not autoimmunity) as an important cause of gestational diabetes mellitus. This study aimed to compare T-helper cells 1 and 2 cytokines and associated antibodies in patients with gestational diabetes mellitus and normal pregnant women. Methods: This cross-sectional study was performed on 45 female patients with GDM and 45 healthy pregnant women in Bandar Abbas, Iran, from 2008- 2009. The exclusion criteria were presence of any infectious diseases or autoimmune disorders such as SLE or RA. Present and past medical histories were taken from the participants thorough physical examination. Blood samples (10 mL) were drawn and sent to laboratory for measuring serum IgE, IgG1, IgG2, IgG3, IgG4, interleukin-10 (IL-10), interleukin-12 (IL-12), transforming growth factor-beta (TGF1), and interferon-gamma (IFN) measurements. T-test and Kolmogorov-Smirnov test were used for data analysis. Results: The mean age of the patients with GDM and healthy pregnant women was 32.5 and 27.9 yrs, respectively. T-helper 1 and 2 associated antibodies and cytokines had no significant differences between the case and control groups. Conclusion: The changes in T-helper 1 and 2 associated antibodies and cytokines are not associated with gestational diabetes mellitus and could not be considered as a predictor for gestational diabetes mellitus

Quality of Verbal communication of health care team with hospitalized children under 3

Background and aimFor different reasons, children may experience hospitalization. With respect to the importance of human relationships and verbal communication in this group for creating confidence and a sense of security with healthcare team, this descriptive study was conducted to identify the quality of verbal communication of the team with hospitalized children under 3 in 2008.  Materials and methods253 nurses and 87 physicians working in pediatric wards of hospitals affiliated to Tehran University of Medical Sciences took part. Data collection tools included a demographic questionnaire and a verbal communication checklist in 3 levels: good, moderate and poor. The checklist was designed for 2 age groups (0-1 and 1-3) to evaluate age differences and communication needs more accurately. Chi-square and exact Fisher tests were used for data analysis. Data were analyzed by SPSS 11. Findings%41.9 and %60.8 of nurses had poor communication with children 0-1 and 1-3 respectively. %42.3 of head nurses had good communication with children 0-1 and 1-3. %38.4 and %48.9 of physicians had good communication with children 0-1 and 1-3 respectively. A significant correlation was found between the verbal communication quality of nurses and such demographic variables as having children, educational level and shift time as well as of head nurses and educational level (