974 research outputs found

    SUSTAINABLE DEVELOPMENT AND THE PROCESS OF JUSTIFYING CHOICES IN A CONTROVERSIAL UNIVERSE

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    All in all, neither the path of the generic principle nor that of the reduction to existing principles would appear to be fully satisfactory as the basis for establishing the legitimacy of sustainable development or as a way of making sustainability a principle of legitimacy by its own. We should probably resign ourselves to seeing in this idea a composite construction, still striving towards the formation of a new "superior common principle", without this principle yet being able to be completely clarified and validated. What we have here is an example of the sort of "compromise" described by Boltanski and Thévenot (1991, p.338): "In the compromise, the participants abandon the idea of clarifying the principle of their agreement but endeavour to maintain a frame of mind aiming at the common good." If we want to consolidate the compromise developing around sustainability, it would be well advised to seek the support of tests using well-formed objects. To this end, steps should be taken to move the emphasis away from long-term and unknowable sustainability requirements and closer to secondbest criteria focused on the transitional developments and possible risks of intentional human action, the ways of managing the linking of the different temporalities in play -- as regards the biophysical phenomena, their understanding and the main worlds of legitimacy (Godard, 1992) -- and the introduction of deliberation within the present generations as to what they feel best describes their identity, those things they would like to pass on

    A Very Low Resource Language Speech Corpus for Computational Language Documentation Experiments

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    Most speech and language technologies are trained with massive amounts of speech and text information. However, most of the world languages do not have such resources or stable orthography. Systems constructed under these almost zero resource conditions are not only promising for speech technology but also for computational language documentation. The goal of computational language documentation is to help field linguists to (semi-)automatically analyze and annotate audio recordings of endangered and unwritten languages. Example tasks are automatic phoneme discovery or lexicon discovery from the speech signal. This paper presents a speech corpus collected during a realistic language documentation process. It is made up of 5k speech utterances in Mboshi (Bantu C25) aligned to French text translations. Speech transcriptions are also made available: they correspond to a non-standard graphemic form close to the language phonology. We present how the data was collected, cleaned and processed and we illustrate its use through a zero-resource task: spoken term discovery. The dataset is made available to the community for reproducible computational language documentation experiments and their evaluation.Comment: accepted to LREC 201

    Spatial Variation in Distribution and Growth Patterns of Old Growth Strip-Bark Pines

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    Postindustrial rises in CO2 have the potential to confound the interpretation of climatically sensitive tree-ring chronologies. Increased growth rates observed during the 20th century in strip-bark trees have been attributed to CO2 fertilization. Absent in the debate of CO2 effects on tree growth are spatially explicit analyses that examine the proximate mechanisms that lead to changes in rates of tree growth. Twenty-seven pairs of strip-bark and companion entire-bark trees were analyzed in a spatially explicit framework for abiotic environmental correlates. The strip-bark tree locations were not random but correlated to an abiotic proxy for soil moisture. The strip-bark trees showed a characteristic increase in growth rates after about 1875. Furthermore, the difference in growth rates between the strip-bark trees and entire-bark companions increased with increasing soil moisture. A possible mechanism for these findings is that CO2 is affecting water-use efficiency, which in turn affects tree-ring growth. These results point to the importance of accounting for microsite variability in analyzing the potential role of CO2 in governing growth responses

    CalFUSE v3: A Data-Reduction Pipeline for the Far Ultraviolet Spectroscopic Explorer

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    Since its launch in 1999, the Far Ultraviolet Spectroscopic Explorer (FUSE) has made over 4600 observations of some 2500 individual targets. The data are reduced by the Principal Investigator team at the Johns Hopkins University and archived at the Multimission Archive at Space Telescope (MAST). The data-reduction software package, called CalFUSE, has evolved considerably over the lifetime of the mission. The entire FUSE data set has recently been reprocessed with CalFUSE v3.2, the latest version of this software. This paper describes CalFUSE v3.2, the instrument calibrations upon which it is based, and the format of the resulting calibrated data files.Comment: To appear in PASP; 29 pages, 13 figures, uses aastex, emulateap

    The new vertebrate CYP1C family : cloning of new subfamily members and phylogenetic analysis

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    Author Posting. © The Authors, 2005. This is the author's version of the work. It is posted here by permission of Elsevier B. V. for personal use, not for redistribution. The definitive version was published in Biochemical and Biophysical Research Communications 331 (2005): 1016-1024, doi:10.1016/j.bbrc.2005.03.231.Two novel CYP1 genes from teleost fish constituting a new subfamily have been cloned. These paralogous sequences are designated CYP1C1 and CYP1C2. Both genes were initially obtained from untreated scup Stenotomus chrysops tissues by RT-PCR and RACE. Scup CYP1C1 and CYP1C2 code for 524 and 525 amino acids, respectively, and share 80-81% identity at the nucleotide and amino acid levels. Orthologues of CYP1C1 and CYP1C2 were identified in genome databases for other fish species, and both CYP1B1 and CYP1C1 were cloned from zebrafish (Danio rerio). Phylogenetic analysis shows that CYP1Cs and CYP1Bs constitute a sister clade to the CYP1As. Analysis of sequence domains likely to have functional significance suggests the two CYP1Cs in scup may have catalytic functions and/or substrate specificity that differ from each other and from those of mammalian CYP1Bs or CYP1As. RT-PCR results indicate that CYP1C1 and CYP1C2 are variously expressed in several scup organs.This work was supported by EPA grant R 827102-01-0 and NIH grants 5 P42-ES07381 and ES04696. JVG is supported by a Ruth L. Kirschstein NRSA Fellowship (F32 ES012794)

    Airway remodelling assessed by sputum and high resolution computed tomography in asthma and COPD

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    It is not known whether sputum elastase, metalloproteinase (MMP)-9 and tissue-inhibitor metalloproteinase (TIMP)-1 are related to structural changes of the airways, as assessed by high-resolution computed tomography (HRCT) scan. The relationships between these markers and the magnitude of structural changes of the airways in asthma and chronic obstructive pulmonary disease (COPD) were assessed. Induced sputum and HRCT scan were performed in 30 asthmatics (14 mild and 16 severe) and in 12 patients with COPD. A greater extent of HRCT scan abnormalities was found in COPD than in severe and mild asthmatics. HRCT scan abnormalities correlated with the degree of airway obstruction in COPD and in severe asthma. HRCT scan abnormalities also correlated with the levels of sputum elastase both in COPD and in severe asthma. HRCT scan abnormalities were associated with sputum MMP-9/TIMP-1 ratio in mild asthma, severe asthma and COPD. In conclusion, this study demonstrates that sputum elastase and the metalloproteinase-9/tissue-inhibitor metalloproteinase-1 ratio are associated with the magnitude of high-resolution computed tomography scan abnormalities of the airways in asthma and chronic obstructive pulmonary disease, and suggests that the levels of these markers reflect the extent of structural changes of the airway

    Reading Videogames as (authorless) Literature

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    This article presents the outcomes of research, funded by the Arts and Humanities Research Council in England and informed by work in the fields of new literacy research, gaming studies and the socio-cultural framing of education, for which the videogame L.A. Noire (Rockstar Games, 2011) was studied within the orthodox framing of the English Literature curriculum at A Level (pre-University) and Undergraduate (degree level). There is a plethora of published research into the kinds of literacy practices evident in videogame play, virtual world engagement and related forms of digital reading and writing (Gee, 2003; Juul, 2005; Merchant, Gillen, Marsh and Davies, 2012; Apperley and Walsh, 2012; Bazalgette and Buckingham, 2012) as well as the implications of such for home / school learning (Dowdall, 2006; Jenkins, 2006; Potter, 2012) and for teachers’ own digital lives (Graham, 2012). Such studies have tended to focus on younger children and this research is also distinct from such work in the field in its exploration of the potential for certain kinds of videogame to be understood as 'digital transformations' of conventional ‘schooled’ literature. The outcomes of this project raise implications of such a conception for a further implementation of a ‘reframed’ literacy (Marsh, 2007) within the contemporary curriculum of a traditional and conservative ‘subject’. A mixed methods approach was adopted. Firstly, students contributing to a gamplay blog requiring them to discuss their in-game experience through the ‘language game’ of English Literature, culminating in answering a question constructed with the idioms of the subject’s set text ‘final examination’. Secondly, students taught their teachers to play L.A. Noire, with free choice over the context for this collaboration. Thirdly, participants returned to traditional roles in order to work through a set of study materials provided, designed to reproduce the conventions of the ‘study guide’ for literature education. Interviews were conducted after each phase and the outcomes informed a redrafting of the study materials which are now available online for teachers – this being the ‘practical’ outcome of the research (Berger and McDougall, 2012). In the act of inserting the study of L.A. Noire into the English Literature curriculum as currently framed, this research moves, through a practical ‘implementation’ beyond longstanding debates around narratology and ludology (Frasca, 2003; Juul, 2005) in the field of game studies (Leaning, 2012) through a direct connection to new literacy studies and raises epistemological questions about ‘subject identity’, informed by Bernstein (1996) and Bourdieu (1986) and the implications for digital transformations of texts for both ideas about cultural value in schooled literacy (Kendall and McDougall, 2011) and the politics of ‘expertise’ in pedagogic relations (Ranciere, 2009, Bennett, Kendall and McDougall, 2012a)

    Three-dimensional high-resolution quantitative microscopy of extended crystals

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    International audienceHard X-ray lens-less microscopy raises hopes for a non-invasive quantitative imaging, capableof achieving the extreme resolving power demands of nanoscience. However, a limit imposedby the partial coherence of third generation synchrotron sources restricts the sample size tothe micrometer range. Recently, X-ray ptychography has been demonstrated as a solution forarbitrarily extending the fi eld of view without degrading the resolution. Here we show thatptychography, applied in the Bragg geometry, opens new perspectives for crystalline imaging.The spatial dependence of the three-dimensional Bragg peak intensity is mapped and the entiredata subsequently inverted with a Bragg-adapted phase retrieval ptychographical algorithm.We report on the image obtained from an extended crystalline sample, nanostructured froma silicon-on-insulator substrate. The possibility to retrieve, without transverse size restriction,the highly resolved three-dimensional density and displacement fi eld will allow for theunprecedented investigation of a wide variety of crystalline materials, ranging from life scienceto microelectronics

    When Therapy Dogs Provide Virtual Comfort: Exploring University Students’ Insights and Perspectives

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    With the proliferation of canine-assisted interventions and the emphasis placed on the impact of these sessions in bolstering the well-being of visitors to sessions, especially university students, it can be easy to overlook just how participating in one of these sessions is experienced by participants. Capturing participants’ experiences is important as this holds the potential to inform program design and delivery and elucidate mechanisms within the intervention that were found to be especially efficacious. Forging new empirical terrain, this study explored the insights and perceptions of 469 undergraduate students who participated in a virtual canine-assisted stress-reduction intervention at a mid-size western Canadian university. Participants were randomly assigned to synchronous or asynchronous and dog or no-dog conditions and were asked to share their views of their experience by rating statements and responding to open-ended prompts. Thematic content analysis of findings revealed that a virtual canine-assisted intervention was well received by participants. Participants in the synchronous condition with a dog reported more favorable well-being benefits, as compared with participants in the asynchronous condition with a dog and with participants in both the synchronous and asynchronous conditions without a dog. Implications of these findings hold relevance for supporting geographically remote students and students for whom attending virtual sessions is the only option given barriers preventing them from in-person attendance. Correspondingly, considerations of the role of the handler and of animal welfare are presented
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