10 research outputs found
Stereoselective Synthesis of 2-Acetamido-1,2-dideoxyallonojirimycin (DAJNAc), a New Potent Hexosaminidase Inhibitor
- Author
- Afarinkia K.
- Aguilar-Moncayo M.
- Aguilar-Moncayo M.
- Aguilar-Moncayo M.
- Al-Rawi S.
- Alex de la Fuente
- Alfonso P.
- Antoni Riera
- Asano N.
- Bagal S. K.
- Benito J. M.
- Best D.
- Carmen Ortiz Mellet
- Castilla J.
- Clark N. E.
- Compain P.
- Dragutan I.
- Fleet G. W. J.
- Fleet G. W. J.
- Gaertner M.
- GarcĂa-Moreno M. I.
- Glawar A. F. G.
- Gloster T. M.
- Gnamm C.
- Gradnig G.
- Hanover J. A.
- Horne G.
- Jiménez Blanco J. L.
- Johannsen M.
- JosĂ© M. GarcĂa Fernández
- Kajimoto T.
- Kang S. H.
- Karjalainen O. K.
- Karjalainen O. K.
- Liang P.-H.
- Liu F.
- Liu J.
- Luan Z.
- Luan Z.
- Martin R.
- Martin R.
- Palyam N.
- Pearson M. S. M.
- Reese T. A.
- Ruben Martin
- Schueller A. M.
- Steiner A. J.
- StĂĽtz A. E.
- StĂĽtz A. E.
- Sánchez-Fernández E. M.
- Sánchez-Fernández E. M.
- Takai T.
- Teresa Mena-Barragán
- Terinek M.
- Tiscornia G.
- Tomasic I. B.
- Tropak M. B.
- Tropak M. B.
- Trost B. M.
- Trost B. M.
- Wells L.
- Winchester B. G.
- Xavier Verdaguer
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
Full text linkSynthesis of 2-acetamido-1,2-dideoxy-d-galacto-nojirimycin [DGJNAc] from d-glucuronolactone: the first sub-micromolar inhibitor of α-N-acetylgalactosaminidases
- Publication venue
- Publication date
- 01/01/2010
- Field of study
No full text2-Acetamido-1,2-dideoxy-d-galacto-nojirimycin [DGJNAc], prepared in 20% overall yield from d-glucuronolactone, is the first potent competitive sub-micromolar inhibitor of α-N-acetyl-galactosaminidases (Ki 0.081 μM from chicken liver, Ki 0.136 μM from Charonia lampas). DGJNAc is a good competitive-whereas the enantiomer l-DGJNAc is a very weak but non-competitive-inhibitor of β-hexosaminidases. © 2010
1,2:3,4-Di- O
- Author
- Publication venue
- 'International Union of Crystallography (IUCr)'
- Publication date
- Field of study
No full text1,2:3,4-Di- O
- Author
- Publication venue
- 'International Union of Crystallography (IUCr)'
- Publication date
- Field of study
No full textNine of 16 Stereoisomeric Polyhydroxylated Proline Amides Are Potent β- N
- Author
- Andreas F. G. Glawar
- Aoyama T.
- Atsushi Kato
- Ayers B. J.
- Banerjee P. S.
- Benjamin J. Ayers
- Best D.
- Bleriot Y.
- Boyd R. E.
- Cecioni S.
- Chu-Yi Yu
- Clark N. E.
- Ganesan M.
- George W. J. Fleet
- Glawar A. F. G.
- Glawar A. F. G.
- Goddard-Borger E. D.
- Greco M.
- Groves J. A.
- Horsch M.
- Isao Adachi
- Jenkinson S. F.
- Kalamkar N. B.
- Ke W.
- Kitahara T.
- Kitamura Y.
- Knapp S.
- Kolter T.
- Kudo T.
- Le Manach C.
- Le Merrer Y.
- Li H.
- Liang P.-H.
- Liu J.
- Liu T.
- Long D. D.
- Ma J.
- Ma Z.
- Ma Z.
- Mark R. Wormald
- Martinez R. F.
- Matsuura D.
- McCort I.
- Mondon M.
- Nigel Ngo
- Nishimura Y.
- Pereira A. C. d. S.
- Pluvinage B.
- R. Fernando MartĂnez
- Rauter A. P.
- Robert J. Nash
- Rountree J. S. S.
- Sarah F. Jenkinson
- Shilvock J. P.
- Shing T. K. M.
- Shinpei Nakagawa
- Slamova K.
- Stocker B. L.
- Stubbs K. A.
- Sugiyama M.
- Tatsuta K.
- Terry D. Butters
- Tsou E.-L.
- Umezawa H.
- Usuki H.
- Vocadlo D. J.
- Win-Mason A. L.
- Xu D. D.
- Yin D.-S.
- Zhu J.-S.
- Zilei Liu
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textSynthesis from d
- Author
- Akihide Yoshihara
- Andreas F. G. Glawar
- Asano N.
- Atsushi Kato
- Bashyal B. P.
- Best D.
- Brimacombe J. S.
- Browning S.
- Browning S.
- Carpenter N. M.
- Cigdem Y.
- Daniel P. F.
- Dekaris V.
- diBello I. C.
- Edgeley D. S.
- Elbein A. D.
- Evans G. B.
- Fleet G. W. J.
- George W. J. Fleet
- Gerber-Lemaire S.
- Gullapalli P.
- Isao Adachi
- Izumori K.
- Jenkinson S. F.
- Kazuya Akimitsu
- Ken Izumori
- Krämer B.
- Lavagnino E. R.
- Lee J. C.
- Lenagh-Snow G. M. J.
- Lenagh-Snow G. M. J.
- Lenagh-Snow G. M. J.
- Li Z. C.
- Loffler K.
- Mahal S. P.
- Mark R. Wormald
- Menavuvu B. T.
- Mercer T. B.
- Nash R. J.
- Noelia AraĂşjo
- Oomizu S.
- Palamarczyk G.
- Pandey G.
- R. Fernando MartĂnez
- Rao D.
- Santos F. M.
- Sarah F. Jenkinson
- Shinpei Nakagawa
- Shrihari P.
- Sun J. Y.
- Terry D. Butters
- Wang X.
- Watson A. A.
- Winchester B.
- Wrodnigg T. M.
- Ye S. J.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full text3-Fluoroazetidinecarboxylic Acids and trans,trans-
- Author
- Akira Kaji
- Alam M. P.
- Albert R.
- Andersen S. M.
- Anxionnat B.
- Asano N.
- Asano N.
- Atsushi Kato
- Awale S.
- Ayers B. J.
- Backer D. C.
- Baek S. H.
- Bessonov K.
- Best D.
- Buck K. W.
- Buer B. C.
- Buku A.
- Card P. J.
- Carmichael J.
- Chakraborty T. K.
- Chakraborty T. K.
- Chakraborty T. K.
- Champagne P.
- Chang D.
- Chu-Yi Yu
- Claridge T. D. W.
- Cohen S.
- Cohen S.
- Couty F.
- Dasuri K.
- Drouillat B.
- D’Hooghe M.
- Egli M.
- Fowden L.
- George W. J. Fleet
- Glawar A. F. G.
- Glawar A. F. G.
- Gottlieb H. E.
- Hagmann W. K.
- Hara R.
- Hickey E. R.
- Hodgson D. M.
- Isao Adachi
- Jasinski M.
- Kaji A.
- Kato A.
- Kern N.
- Kim D. W.
- Kiss L.
- Kollonit J.
- Kovac P.
- Kováč P.
- Lee J. C.
- Lenagh-Snow G. M. J.
- Lenagh-Snow G. M. J.
- Lensen N.
- Li Y.-X.
- Li Y.I-X.
- Liang T.
- Lo C.
- Loenarz C.
- Mahe O.
- Manta S.
- Mark R. Wormald
- Marsh E. N. G.
- Martinek T. A.
- MartĂnez R. F.
- Mastihubová M.
- Metkar S. D.
- Nakajima T.
- Nash R. J.
- Pan S.
- Parsy C.
- Phillips D. P.
- Pizzonero M.
- Powell N. H.
- Prell E.
- Rajulu G. G.
- Reddy B. V. S.
- Risseeuw M. D. P.
- Rjabovs V.
- Rodgers K.
- Rubenstein E.
- Rubenstein E.
- Rubenstein E.
- Rubenstein E.
- Rzasa R. M.
- Sarah F. Jenkinson
- Shibasaki T.
- Smith M. D.
- Stankovic S.
- Sun Y.
- Takhi M.
- Tom Vermaas
- Tysoe C.
- Van Hende E.
- Vranova V.
- Wang J.
- Weids A. J.
- Yukako Hata
- Yukiko Kurashima
- Zhao J.
- Zilei Liu
- Zukauskaite A.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textSynthesis of Eight Stereoisomers of Pochonicine: Nanomolar Inhibition of β- N
- Author
- Apelqvist T.
- Argyropoulos N. G.
- Atsushi Kato
- Bessodes M.
- Best D.
- Blickenstaff R. T.
- Brandi A.
- Burk M. J.
- Buse M. G.
- Chu-Yi Yu
- Davis B.
- Delso I.
- Desvergnes S.
- Donohoe T. J.
- D’Alonzo D.
- Fleet G. W. J.
- Francis X. Wilson
- Fujiwara T.
- George W. J. Fleet
- Glawar A. F. G.
- Graeme Horne
- Hart G. W.
- Hernández J. N.
- Holzapfel C. W.
- Horsch M.
- Hu X.-G.
- HĂĄkansson A. E.
- Ikota N.
- Isao Adachi
- Jenkinson S. F.
- Jian-She Zhu
- Kaliappan K. P.
- Kitamura Y.
- Kotsuki H.
- Ma Z.
- Macauley M. S.
- Merino P.
- Merino P.
- Merzendorfer H.
- Mirrington R. N.
- Nash R. J.
- Nigama S. C.
- Petrier C.
- Podolan G.
- Randazzo G.
- Rast D. M.
- Renate van Well
- Restorp P.
- Revuelta J.
- Shinpei Nakagawa
- Singh O. V.
- Siro J. G.
- Slámová K.
- Stafford J. A.
- Stecko S.
- Stecko S.
- Teruhiko Nitoda
- Tsou E.-L.
- Usuki H.
- Vosseller K.
- Wei Chen
- Wells L.
- Woynarowska B.
- Woynarowska B.
- Xiang-Guo Hu
- Yadav J. S.
- Yadav J. S.
- Yadav J. S.
- Yu C.-Y.
- Yue-Mei Jia
- Yuzwa S. A.
- Yuzwa S. A.
- Zhao W.-B.
- Zou W.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textA compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues
- Author
- A Ahmed
- A Alex
- A Avenoza
- A Avenoza
- A Avenoza
- A Avenoza
- A Avenoza
- A Avenoza
- A Avenoza
- A Banfi
- A Basso
- A Berkessel
- A Bernardi
- A Chen
- A De Mesmaeker
- A Defant
- A Dondoni
- A Dondoni
- A Dondoni
- A Duréault
- A Franconetti
- A Ghorai
- A Ghorai
- A Grauer
- A Grauer
- A Grauer
- A Hui
- A Jenmalm
- A Kilonda
- A Kyas
- A Lopez-Perez
- A Mann
- A Mann
- A MĂĽller
- A Niethe
- A Orsato
- A Padwa
- A Padwa
- A Reichelt
- A Renard
- A Renard
- A Rives
- A Rosenthal
- A Rosenthal
- A Ruffoni
- A Scaffidi
- A Scaffidi
- A Scaffidi
- A Scaffidi
- A Schrey
- A ShafĂee
- A Vescovi
- A Wohlrab
- A Žukauskaitė
- AA Cant
- AA Edwards
- AA Edwards
- AA Edwards
- AA Edwards
- AA Edwards
- AA Grauer
- AA Grauer
- AB Cheikh
- AB Smith III
- ACB Burtoloso
- ACB Burtoloso
- AD Knijnenburg
- AF Parsons
- AFG Glawar
- AG Hedenetz
- AG Pepper
- AG Schultz
- AGM Barrett
- AGM Barrett
- AI Jimenez
- AJ Fairbanks
- AJ Jensen
- AJ Lawrence
- AM Gil
- AM Gomez
- AM Palmer
- AN Tkachenko
- ANV Nhien
- AP Dobbs
- AP Kozikowski
- AP Kozikowski
- AR Genady
- AR Williamson
- AT Carmona
- AW McCulloch
- AY Sukhorukov
- B Aguilera
- B Alcaide
- B Alcaide
- B Alcaide
- B Bellier
- B Degel
- B Drouillat
- B Ferla La
- B Jagadeesh
- B Jagadeesh
- B Jagannadh
- B Krzyzanowska
- B Lastdrager
- B Liu
- B Lopez-Ortega
- B Pillai
- B Pillai
- B Raju
- B Wang
- B Wang
- BA Mayes
- BB Snider
- BE Cantrell
- BM Malle
- BM Skead
- BP Bandgar
- BP Bashyal
- BW Lee
- C Agami
- C Agami
- C Alcaraz
- C Baldauf
- C Barfoot
- C Barfoot
- C Bubert
- C Bughin
- C Caupene
- C Chevrier
- C Cramay
- C Cramay
- C Gasch
- C Gasch
- C Gasch
- C Gravier-Pelletier
- C Herdeis
- C Herdeis
- C Herdeis
- C Juli
- C Kadouri-Puchot
- C MĂĽller
- C Palomo
- C Pasquarello
- C Reiriz
- C Schaub
- C Taillefumier
- C Taillefumier
- C Toniolo
- C Verhagen
- C Vogel
- C Zhong
- CA Carson
- CG Caldwell
- CJF Bichard
- CM Evina
- CM Taylor
- CM Timmers
- CR Johnson
- CR Woods
- CU Kim
- D Best
- D Braga
- D Casabona
- D Colombani
- D Enders
- D Mostowicz
- D Phillips
- D Roche
- D Scholz
- D Seebach
- D Seebach
- D Seebach
- D Seebach
- D Seebach
- D Seebach
- D Staedler
- D Wiktelius
- D Yoo
- D Yoo
- D-M Lu
- DC Schmitt
- DD Long
- DD Long
- DD Long
- DD Long
- DEA Brittain
- DH Appella
- DJ Aitken
- DJ Hill
- DJ Wustrow
- DL Siehl
- DM Walker
- DP Walker
- DR Williams
- DS Radchenko
- DS Radchenko
- DW Knight
- DW Norbeck
- DW Norbeck
- E Alonso
- E Buñuel
- E Farber
- E ForrĂł
- E Leemans
- E LobatĂłn
- E Locardi
- E Lohof
- E Lohof
- E Lohof
- E Lohof
- E Luethi
- E Rozners
- E Ă“sz
- E-F Fuchs
- E-F Fuchs
- E-F Fuchs
- EA Girnys
- EA Wydysh
- ED Naydenova
- EG Roedern von
- EG Roedern von
- EL Dane
- F Benfatti
- F Bouillere
- F Brackmann
- F Burkhart
- F Cagide-FagĂn
- F Caputo
- F De Nanteuil
- F Douelle
- F Durrat
- F Felluga
- F Fringuelli
- F Fujimura
- F Fülöp
- F Fülöp
- F Gnad
- F Lecornue
- F Lehmann
- F Marcelo
- F Osterkamp
- F Oualid El
- F Oualid El
- F Oualid El
- F Peri
- F Schweizer
- F Sicherl
- F-D Boyer
- FP Cruz da
- FS Gonzalez
- G Baschang
- G Benedek
- G Casiraghi
- G Casiraghi
- G Imre
- G Karig
- G Lamanna
- G Lemiére
- G Liao
- G Limberg
- G Pandey
- G Pattenden
- G Rassu
- G Timpano
- G Wang
- G Wang
- G Wuitschik
- GA Kraus
- George W. J. Fleet
- GH Lee
- GH Zhao
- GJ Sanjayan
- GL Zhang
- GM Grotenbreg
- GM Grotenbreg
- GM Grotenbreg
- GM Grotenbreg
- GN Austin
- GP Rozing
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- GP Rozing
- GR Boyce
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- Guchteneere De
- GVM Sharma
- GVM Sharma
- GVM Sharma
- GVM Sharma
- GWJ Fleet
- GWJ Fleet
- GWJ Fleet
- GWJ Fleet
- H Adachi
- H Adkins
- H Ducatel
- H Haruyama
- H Hashizume
- H Ishida
- H Ishikawa
- H Kessler
- H Kim
- H Li
- H Masaki
- H Návarová
- H Sano
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- H Tanaka
- H Umezawa
- H Vorbrueggen
- H Wamhoff
- H Wamhoff
- H Wu
- H Xu
- H Yanagisawa
- H-U Reissig
- HM Deutsch
- HP Weber
- HP Wessel
- HS Khadem El
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- HY Wang
- I Bruce
- I Collado
- I Lundt
- I Lundt
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- IS Kulaev
- J Bongaerts
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- J Xie
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- J Yoshimura
- J Yoshimura
- J Yoshimura
- J-B Behr
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- J-W Shen
- JA Burkhard
- JA Burkhard
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- JA Monn
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- JE Baldwin
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- JP Burkhart
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- JP Shilvock
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- JR Brisson
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- JS Kaltenbronn
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- JW Frazier
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- K Achiwa
- K Clinch
- K Furuta
- K Gademann
- K Gajcy
- K Gogoi
- K Hammer
- K Heyns
- K Heyns
- K Isono
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- K Namba
- K Ohba
- K Sakata
- K Takahashi
- K Takahashi
- K Tatsuta
- K Tomita
- K Yamatsugu
- K Yamazaki
- K Yoshikawa
- K Zhang
- K Zhang
- K-I Kim
- KB Lindsay
- KE Henegar
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- KP Fondekar
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- L Cipolla
- L Cipolla
- L Guo
- L Guo
- L Guo
- L Guo
- L Kiss
- L Kiss
- L Mallesha
- L Otvos
- L Ouazzani-Chadi
- L Rizzi
- L Somsák
- L Somsák
- L Szabo
- L Thander
- L Wick
- LA Mukhamedova
- LA Mukhamedova
- LA Paquette
- LC Carvalho
- LF Bornaghi
- LG Revelskaya
- LH Werner
- LH Zalkow
- LKA Pilsl
- LM Likhosherstov
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- M Andreini
- M Andreini
- M Bartels
- M Caroff
- M Chandler
- M Colombini
- M Egli
- M Fujii
- M Gregoriou
- M Hartmann
- M Hatano
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- M Ikbal
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- M Kordes
- M Koutsaplis
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- M Marastoni
- M Martinková
- M Maurs
- M Menand
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- M Nakajima
- M PalkĂł
- M Patzel
- M Popsavin
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- M Sasaki
- M Sasaki
- M Sasaki
- M Sasaki
- M Shiokazi
- M Shiozaki
- M Shiozaki
- M Shiozaki
- M Shoji
- M Shoji
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- M Stöckle
- M Takeda
- M Tanaka
- M Tiecco
- M Ueda
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- M Yamashita
- M Yamashita
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- M-C Cheng
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- MI Simone
- MI Simone
- MI Simone
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- MP DeNinno
- MP DeNinno
- MP Watterson
- MP Watterson
- MR Johnson
- MSM Timmer
- MT Reetz
- MV Itzstein
- N Basarić
- N Chida
- N Defacqz
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- O Blanco
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- O Songis
- O Songis
- P Bravo
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- P Tanui
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- P Wipf
- P Wipf
- P Yuan
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- PG Vasudev
- PH Seeberger
- PJ Wentworth
- PR Krishna
- PS Ramamoorthy
- PV Fish
- PV Reddy
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- PW Smith
- R Baron
- R Bream
- R Feldhoff
- R Galeazzi
- R Hanselmann
- R Haubner
- R Haubner
- R Iwase
- R Luisi
- R Rais
- R Sakai
- R Soengas
- R Sudo
- R Tamura
- R Threlfall
- R Threlfall
- R Threlfall
- RA Jockusch
- RA Miller
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- RD Allan
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- RR Schmidt
- RR Schmidt
- RS Roy
- S Abele
- S Cardana
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- S Chandrasekhar
- S Chandrasekhar
- S Chandrasekhar
- S Choi
- S Czernecki
- S Fustero
- S Fustero
- S Gyémánt
- S GyĂłnfalvi
- S Hanessian
- S Hanessian
- S Hanessian
- S Hanessian
- S Horvat
- S Hussain
- S Isoda
- S Knapp
- S Knapp
- S Omura
- S Pilgrim
- S Prasad
- S Richards
- S Sabesan
- S Schröder
- S Semrau
- S Seto
- S Shinagawa
- S Stamm
- S Venkatraman
- S Yamada
- S Yamazaki
- S Zen
- S-I Nishimura
- SAW Gruner
- SAW Gruner
- SAW Gruner
- SB Bedford
- SC Bergmeier
- SD Haveli
- SD Lucas
- SD Lucas
- SD Lucas
- SF Barker
- SF Jenkinson
- SG Davies
- SG Davies
- SG Davies
- SG Davies
- SH Gellman
- SJ Hecker
- SK Pandey
- SK Pandey
- SL Bogen
- SM Sakya
- SV Ley
- SV O’Neil
- SW Johnson
- SW Johnson
- SW Johnson
- SW Johnson
- T Bach
- T Fuchss
- T Hirata
- T Hiyama
- T Kano
- T Kawabata
- T Komori
- T Lazaridis
- T Miura
- T Nagata
- T Nishikawa
- T Rammeloo
- T Shibasaki
- T Shinada
- T Umezawa
- T Wakimoto
- T Yamamoto
- T Yi
- T Yoshioka
- T Zhang
- TA Brandt
- TA Connors
- TA Martinek
- TB Kovachev
- TD Copeland
- TDW Claridge
- TDW Claridge
- TDW Claridge
- TJ Donohoe
- TJ Miles
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TK Chakraborty
- TM Williams
- TM Williams
- TQ Gregar
- TT Denton
- TW Brandstetter
- TW Brandstetter
- TY Chan
- U Bösche
- U Jahn
- U Meyer
- U Schöllkopf
- U Voigtmann
- V André
- V Capriati
- V Jeanneret
- V Nair
- V Udumula
- VA Efimov
- VD Chaudhari
- VI Tyvorskii
- VP Vyavahare
- VS Kubyshkin
- VSC Yeh
- VU Schöllkopf
- W Cocker
- W Funcke
- W Lee
- W Lew
- W Lew
- W Lin
- W Oldfield
- W Schmid
- W Traube
- W Vollmer
- WH Pearson
- WMZ Reckendorf
- WS Horne
- X Wu
- X-S Ye
- XF Liang
- Y Arakawa
- Y Auberson
- Y Blériot
- Y Chu
- Y Fu
- Y Igarashi
- Y Iwabuchi
- Y Kawahata
- Y Maeda
- Y Matsushima
- Y Nitta
- Y Ohfune
- Y Ohfune
- Y Suhara
- Y Suhara
- Y Suhara
- Y Suhara
- Y Suhara
- Y Takeuchi
- Y Vera-Ayoso
- Y Vera-Ayoso
- Y Wang
- Y Wang
- Y Yoshimura
- Y-K Chung
- YA Knirel
- YL Li
- YS Agasimundin
- Z Guo
- Z Györgydeák
- Z Szakonyi
- Z Szakonyi
- Z Szakonyi
- Z Szakonyi
- Z-G Gao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
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