Computer program for parameter optimization

Flexible, large scale digital computer program was designed for the solution of a wide range of multivariable parameter optimization problems. The program has the ability to solve constrained optimization problems involving up to one hundred parameters

ODIN: Optimal design integration system

The report provides a summary of the Optimal Design Integration (ODIN) System as it exists at Langley Research Center. A discussion of the ODIN System, the executive program and the data base concepts are presented. Two examples illustrate the capabilities of the system which have been exploited. Appended to the report are a summary of abstracts for the ODIN library programs and a description of the use of the executive program in linking the library programs

Program user's manual for optimizing the design of a liquid or gaseous propellant rocket engine with the automated combustor design code AUTOCOM

This computer program manual describes in two parts the automated combustor design optimization code AUTOCOM. The program code is written in the FORTRAN 4 language. The input data setup and the program outputs are described, and a sample engine case is discussed. The program structure and programming techniques are also described, along with AUTOCOM program analysis

Geometry Technology Module (GTM). Volume 1: Engineering description and utilization manual

The geometry technology module (GTM) is described as a system of computerized elements residing in the engineering design integration system library developed for the generation, manipulation, display, computation of mass properties, and data base management of panelled geometry. The GTM is composed of computer programs and associated data for performing configuration analysis on geometric shapes. The program can be operated in batch or demand mode and is designed for interactive use

Star Formation History in two fields of the Small Magellanic Cloud Bar

The Bar is the most productive region of the Small Magellanic Cloud in terms of star formation but also the least studied one. In this paper we investigate the star formation history of two fields located in the SW and in the NE portion of the Bar using two independent and well tested procedures applied to the color-magnitude diagrams of their stellar populations resolved by means of deep HST photometry. We find that the Bar experienced a negligible star formation activity in the first few Gyr, followed by a dramatic enhancement from 6 to 4 Gyr ago and a nearly constant activity since then. The two examined fields differ both in the rate of star formation and in the ratio of recent over past activity, but share the very low level of initial activity and its sudden increase around 5 Gyr ago. The striking similarity between the timing of the enhancement and the timing of the major episode in the Large Magellanic Cloud is suggestive of a close encounter triggering star formation.Comment: 30 pages, 22 figures, accepted for publication in Ap

Geometry Technology Module (GTM). Volume 2: Programmers' manual

For abstract, see N75-17120

Psychiatric genetics and the structure of psychopathology

For over a century, psychiatric disorders have been defined by expert opinion and clinical observation. The modern DSM has relied on a consensus of experts to define categorical syndromes based on clusters of symptoms and signs, and, to some extent, external validators, such as longitudinal course and response to treatment. In the absence of an established etiology, psychiatry has struggled to validate these descriptive syndromes, and to define the boundaries between disorders and between normal and pathologic variation. Recent advances in genomic research, coupled with large-scale collaborative efforts like the Psychiatric Genomics Consortium, have identified hundreds of common and rare genetic variations that contribute to a range of neuropsychiatric disorders. At the same time, they have begun to address deeper questions about the structure and classification of mental disorders: To what extent do genetic findings support or challenge our clinical nosology? Are there genetic boundaries between psychiatric and neurologic illness? Do the data support a boundary between disorder and normal variation? Is it possible to envision a nosology based on genetically informed disease mechanisms? This review provides an overview of conceptual issues and genetic findings that bear on the relationships among and boundaries between psychiatric disorders and other conditions. We highlight implications for the evolving classification of psychopathology and the challenges for clinical translation

The engineering design integration (EDIN) system

A digital computer program complex for the evaluation of aerospace vehicle preliminary designs is described. The system consists of a Univac 1100 series computer and peripherals using the Exec 8 operating system, a set of demand access terminals of the alphanumeric and graphics types, and a library of independent computer programs. Modification of the partial run streams, data base maintenance and construction, and control of program sequencing are provided by a data manipulation program called the DLG processor. The executive control of library program execution is performed by the Univac Exec 8 operating system through a user established run stream. A combination of demand and batch operations is employed in the evaluation of preliminary designs. Applications accomplished with the EDIN system are described

Prediction of sonic boom from experimental near-field overpressure data. Volume 2: Data base construction

A computerized method for storing, updating and augmenting experimentally determined overpressure signatures has been developed. A data base of pressure signatures for a shuttle type vehicle has been stored. The data base has been used for the prediction of sonic boom with the program described in Volume I