Social personalized adaptive e-learning environment : Topolor - implementation and evaluation

This paper presents a quantitative study on the use of Topolor - a prototype that introduces Web 2.0 tools and Facebook-like appearance into an adaptive educational hypermedia system. We present the system design and its evaluation using system usability scale questionnaire and learning behavior data analysis. The results indicate high level of student satisfaction with the learning experience and the diversity of learning activities

BlogForever D5.2: Implementation of Case Studies

This document presents the internal and external testing results for the BlogForever case studies. The evaluation of the BlogForever implementation process is tabulated under the most relevant themes and aspects obtained within the testing processes. The case studies provide relevant feedback for the sustainability of the platform in terms of potential users’ needs and relevant information on the possible long term impact

BlogForever D5.3: User Questionnaires and Reports

This report presents the feedback gathered from third party users during the BlogForever Case Studies. Therefore, the research framework is defined and the case studies results are presented, followed by a summary of conclusions and remarks

CONTRIBUTION OF EMPIRICAL METHODS AND SATELLITE DATA USE FOR ESTIMATING DAILY REFERENCE EVAPOTRANSPIRATION

Στην παρούσα εργασία χρησιμοποιούνται επίγεια και δορυφορικά μετεωρολογικά δεδομένα του έτους 2014 από την περιοχή της Βοιωτίας. Τα επίγεια δεδομένα προέρχονται από τον αυτόματο αγρομετεωρολογικό σταθμό (ΑΑΣ) μέτρησης της εξατμισοδιαπνοής αναφοράς (ΕΤο) του Γεωπονικού Πανεπιστημίου Αθηνών (ΓΠΑ). Τα μετεωρολογικά δορυφορικά δεδομένα (SAT) αντιστοιχούν σε πολύγωνο 0.25οΧ0.25ο εντός του οποίου λειτουργεί και ο ΑΑΣ. Χρησιμοποιώντας τα επίγεια αλλά και τα δορυφορικά δεδομένα, υπολογίσθηκε η ΕΤο με τη μέθοδο FAO-56 PM, αλλά και με τρεις εμπειρικές μεθόδους (Copais, Valiantzas και Hargreaves-Samani) και πραγματοποιήθηκαν συγκρίσεις με σκοπό να αξιολογηθεί η αξιοπιστία των μοντέλων. Ως βάση των συγκρίσεων υιοθετήθηκε η μέθοδος FAO-56 PM με χρήση επίγειων δεδομένων. Από την εργασία προκύπτει ότι τόσο για τα επίγεια όσο και για τα δορυφορικά δεδομένα η μέθοδος Copais δίνει τις καλύτερες εκτιμήσεις ακολουθούμενη από την μέθοδο Valiantzas και με σοβαρή υπερεκτίμηση η Hargreaves-Samani. In the present study we used ground and satellite meteorological data of the year 2014 from the region of Viotia-Greece. The ground data were obtained from the automatic grass reference evapotranspiration station (AAS) of the Agricultural University of Athens. The satellite data (SAT) cover an area of 0,25ο x 0,25ο that includes the AAS. By using the ground and the satellite data we calculated the reference evapotranspiration, ΕΤο, with the method FAO-56 PM and with three empirical methods (Copais, Valiantzas and Hargreaves-Samani). The FAO-56 PM was used as a benchmark method to compare and validate the performances of the others methods. The results show that for both the ground and the satellite data, Copais method is the most accurate followed by Valiantzas and Hargreaves-Samani, indicated by serious overestimation

The role of natural science collections in the biomonitoring of environmental contaminants in apex predators in support of the EU's zero pollution ambition

The chemical industry is the leading sector in the EU in terms of added value. However, contaminants pose a major threat and significant costs to the environment and human health. While EU legislation and international conventions aim to reduce this threat, regulators struggle to assess and manage chemical risks, given the vast number of substances involved and the lack of data on exposure and hazards. The European Green Deal sets a 'zero pollution ambition for a toxic free environment' by 2050 and the EU Chemicals Strategy calls for increased monitoring of chemicals in the environment. Monitoring of contaminants in biota can, inter alia: provide regulators with early warning of bioaccumulation problems with chemicals of emerging concern; trigger risk assessment of persistent, bioaccumulative and toxic substances; enable risk assessment of chemical mixtures in biota; enable risk assessment of mixtures; and enable assessment of the effectiveness of risk management measures and of chemicals regulations overall. A number of these purposes are to be addressed under the recently launched European Partnership for Risk Assessment of Chemicals (PARC). Apex predators are of particular value to biomonitoring. Securing sufficient data at European scale implies large-scale, long-term monitoring and a steady supply of large numbers of fresh apex predator tissue samples from across Europe. Natural science collections are very well-placed to supply these. Pan-European monitoring requires effective coordination among field organisations, collections and analytical laboratories for the flow of required specimens, processing and storage of specimens and tissue samples, contaminant analyses delivering pan-European data sets, and provision of specimen and population contextual data. Collections are well-placed to coordinate this. The COST Action European Raptor Biomonitoring Facility provides a well-developed model showing how this can work, integrating a European Raptor Biomonitoring Scheme, Specimen Bank and Sampling Programme. Simultaneously, the EU-funded LIFE APEX has demonstrated a range of regulatory applications using cutting-edge analytical techniques. PARC plans to make best use of such sampling and biomonitoring programmes. Collections are poised to play a critical role in supporting PARC objectives and thereby contribute to delivery of the EU's zero-pollution ambition.Non peer reviewe

Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry

Background and purpose: Prospectively collected data comparing the safety and effectiveness of individual non-vitamin K antagonists (NOACs) are lacking. Our objective was to directly compare the effectiveness and safety of NOACs in patients with newly diagnosed atrial fibrillation (AF). Methods: In GLORIA-AF, a large, prospective, global registry program, consecutive patients with newly diagnosed AF were followed for 3 years. The comparative analyses for (1) dabigatran vs rivaroxaban or apixaban and (2) rivaroxaban vs apixaban were performed on propensity score (PS)-matched patient sets. Proportional hazards regression was used to estimate hazard ratios (HRs) for outcomes of interest. Results: The GLORIA-AF Phase III registry enrolled 21,300 patients between January 2014 and December 2016. Of these, 3839 were prescribed dabigatran, 4015 rivaroxaban and 4505 apixaban, with median ages of 71.0, 71.0, and 73.0 years, respectively. In the PS-matched set, the adjusted HRs and 95% confidence intervals (CIs) for dabigatran vs rivaroxaban were, for stroke: 1.27 (0.79–2.03), major bleeding 0.59 (0.40–0.88), myocardial infarction 0.68 (0.40–1.16), and all-cause death 0.86 (0.67–1.10). For the comparison of dabigatran vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 1.16 (0.76–1.78), myocardial infarction 0.84 (0.48–1.46), major bleeding 0.98 (0.63–1.52) and all-cause death 1.01 (0.79–1.29). For the comparison of rivaroxaban vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 0.78 (0.52–1.19), myocardial infarction 0.96 (0.63–1.45), major bleeding 1.54 (1.14–2.08), and all-cause death 0.97 (0.80–1.19). Conclusions: Patients treated with dabigatran had a 41% lower risk of major bleeding compared with rivaroxaban, but similar risks of stroke, MI, and death. Relative to apixaban, patients treated with dabigatran had similar risks of stroke, major bleeding, MI, and death. Rivaroxaban relative to apixaban had increased risk for major bleeding, but similar risks for stroke, MI, and death. Registration: URL: https://www.clinicaltrials.gov. Unique identifiers: NCT01468701, NCT01671007. Date of registration: September 2013

Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation. the GLORIA-AF registry

Aim: The SAMe-TT2R2 score helps identify patients with atrial fibrillation (AF) likely to have poor anticoagulation control during anticoagulation with vitamin K antagonists (VKA) and those with scores >2 might be better managed with a target-specific oral anticoagulant (NOAC). We hypothesized that in clinical practice, VKAs may be prescribed less frequently to patients with AF and SAMe-TT2R2 scores >2 than to patients with lower scores. Methods and results: We analyzed the Phase III dataset of the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF), a large, global, prospective global registry of patients with newly diagnosed AF and ≥1 stroke risk factor. We compared baseline clinical characteristics and antithrombotic prescriptions to determine the probability of the VKA prescription among anticoagulated patients with the baseline SAMe-TT2R2 score >2 and ≤ 2. Among 17,465 anticoagulated patients with AF, 4,828 (27.6%) patients were prescribed VKA and 12,637 (72.4%) patients an NOAC: 11,884 (68.0%) patients had SAMe-TT2R2 scores 0-2 and 5,581 (32.0%) patients had scores >2. The proportion of patients prescribed VKA was 28.0% among patients with SAMe-TT2R2 scores >2 and 27.5% in those with scores ≤2. Conclusions: The lack of a clear association between the SAMe-TT2R2 score and anticoagulant selection may be attributed to the relative efficacy and safety profiles between NOACs and VKAs as well as to the absence of trial evidence that an SAMe-TT2R2-guided strategy for the selection of the type of anticoagulation in NVAF patients has an impact on clinical outcomes of efficacy and safety. The latter hypothesis is currently being tested in a randomized controlled trial. Clinical trial registration: URL: https://www.clinicaltrials.gov//Unique identifier: NCT01937377, NCT01468701, and NCT01671007

Observations on Reversible Addition Fragmentation Chain Transfer (RAFT) Polymerisations in Solution and Emulsion

We introduce a geolocation-aware semantic annotation model that extends the existing solutions for spotting and disambiguation of places within user-generated texts. The implemented prototype processes the text of weblog posts and annotates the places and toponyms. It outperforms existing solutions by taking into consideration the embedded geolocation data. The evaluation of the model is based on a set of randomly selected 3,165 geolocation embedded weblog posts, obtained from 1,775 web feeds. The results demonstrate a high degree of accuracy in annotation (87.7%) and a considerable gain (27.8%) in identifying additional entities, and therefore support the adoption of the model for supplementing the existing solutions

Study of the structure and the thermomechanical properties of silicone based nanocomposites

135 σ.Στα πλαίσια της παρούσης διπλωματικής εργασίας μελετήθηκαν υβριδικά συστήματα με ανόργανα μέσα ενίσχυσης πολυσιλοξανών συμπύκνωσης και προσθήκης, με σκοπό το χαρακτηρισμό των θερμικών και μηχανικών τους ιδιοτήτων καθώς και τον εντοπισμό του βέλτιστου κατά περίπτωση συστήματος.In this diploma thesis, hybrid systems of polysiloxane with different types of inorganic reinforcement were studied, in order to characterize their thermal and mechanical properties, as well as to identify the optimal system regarding the respective application.Γεώργιος Ι. Γκότση