Unsaturated soil mechanics in rainfall-induced flow landslides

Rainfall-induced flow landslides in coarse-grained soils pose significant threats to populations and structures due to their high velocities, long travel distance and the absence of definite warning signs during the pre-failure stage. The triggering phase of these phenomena is frequently related to rainfall events which significantly reduce matric suction in the shallower soil layers. In this paper the processes leading to the onset of such phenomena are illustrated and some observations on their modelling are briefly recalled. The failure stage at different scales is then modelled with reference to a case study from southern Italy which draws on high-quality experimental data sets from extensive in situ and laboratory investigation

An anomalous case of S-ICD malfunctioning: A big trouble or a soap bubble?

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Cerebellum and Prematurity: A Complex Interplay Between Disruptive and Dysmaturational Events

The cerebellum plays a critical regulatory role in motor coordination, cognition, behavior, language, memory, and learning, hence overseeing a multiplicity of functions. Cerebellar development begins during early embryonic development, lasting until the first postnatal years. Particularly, the greatest increase of its volume occurs during the third trimester of pregnancy, which represents a critical period for cerebellar maturation. Preterm birth and all the related prenatal and perinatal contingencies may determine both dysmaturative and lesional events, potentially involving the developing cerebellum, and contributing to the constellation of the neuropsychiatric outcomes with several implications in setting-up clinical follow-up and early intervention

Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study

: The identification of high-risk patients in the early stages of infected pancreatic necrosis (IPN) is critical, because it could help the clinicians to adopt more effective management strategies. We conducted a post hoc analysis of the MANCTRA-1 international study to assess the association between clinical risk factors and mortality among adult patients with IPN. Univariable and multivariable logistic regression models were used to identify prognostic factors of mortality. We identified 247 consecutive patients with IPN hospitalised between January 2019 and December 2020. History of uncontrolled arterial hypertension (p = 0.032; 95% CI 1.135-15.882; aOR 4.245), qSOFA (p = 0.005; 95% CI 1.359-5.879; aOR 2.828), renal failure (p = 0.022; 95% CI 1.138-5.442; aOR 2.489), and haemodynamic failure (p = 0.018; 95% CI 1.184-5.978; aOR 2.661), were identified as independent predictors of mortality in IPN patients. Cholangitis (p = 0.003; 95% CI 1.598-9.930; aOR 3.983), abdominal compartment syndrome (p = 0.032; 95% CI 1.090-6.967; aOR 2.735), and gastrointestinal/intra-abdominal bleeding (p = 0.009; 95% CI 1.286-5.712; aOR 2.710) were independently associated with the risk of mortality. Upfront open surgical necrosectomy was strongly associated with the risk of mortality (p < 0.001; 95% CI 1.912-7.442; aOR 3.772), whereas endoscopic drainage of pancreatic necrosis (p = 0.018; 95% CI 0.138-0.834; aOR 0.339) and enteral nutrition (p = 0.003; 95% CI 0.143-0.716; aOR 0.320) were found as protective factors. Organ failure, acute cholangitis, and upfront open surgical necrosectomy were the most significant predictors of mortality. Our study confirmed that, even in a subgroup of particularly ill patients such as those with IPN, upfront open surgery should be avoided as much as possible. Study protocol registered in ClinicalTrials.Gov (I.D. Number NCT04747990)

Study and Implementation of Bremsstrahlung radiation in plasma

The focus of this work is the study of Bremsstrahlung emission happening when a relativistic electron impacts a high-Z target. Although this system has been extensively studied in the hypothesis of a neutral target, a new context of modern research facilities equipped with Multi-Petawatt laser, allowing so to produce multi-GeV electrons, requires us to generalize the study to partially/completely ionized targets (Plasma). In this work are reported the theory necessary to understand the Bremsstrahlung cross-sections in the different electron energy regimes. Making use of the cross-sections and the integrated quantities related to them, I illustrate the implementation of an original Monte-Carlo code for Bremsstrahlung for the PIC code SMILEI and I benchmark it against the theory. Finally, we use it to predict a future APOLLON experiment aiming to produce pair plasma using Bremsstrahlung-generated photons

La disciplina Solvency II

Il presente capitolo offre una panoramica dei principali cambiamenti nella concreta operatività di una compagnia di assicurazione alla luce della introduzione della cornice regolamentare "Solvency II".This chapter aims to provide an overview of the main changes in the management of insurance companies in the light of the introduction of the regulatory framework "Solvency II"

SP576ASSESSMENT OF INTRADIALYTIC HYPOTENSION : A NEW METHOD DERIVED FROM INTRADIALYTIC BLOOD PRESSURE VARIABILITY

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Mechanical properties of PAN-based gel electrolytes: small-amplitude oscillatory shear study

Polymer electrolytes with ionic conductivities on the order of mS cm -1 at room temperature were prepared from the gelification of LiClO4/ethylene carbonate-propylene carbonate (EC-PC) solutions into a poly(acrylonitrile) (PAN) matrix. Oscillating rheological experiments were performed on gels prepared at different solvent/salt molar ratios in order to investigate their mechanical properties. Temperature sweep tests (25-120°C) showed changes in the rheological behaviour that was related to structural transitions. A strong-weak gel transition takes place at about 80°C, independent of salt concentration hence assignable only to the polymeric matrix, This transition is completely reversible during cooling ramps and represents a necessary mechanical property from a processing standpoint. A gel-sol transition was observed at ca. 110°C where both viscoelastic moduli reduce themselves by a factor 100, reporting the formation of a fluid system with G″>G'

Endovesical instillation of platelet rich fibrin for treatment of interstitial cystitis: case report of two patients

Interstitial cystitis, also called painful bladder syndrome, is a chronic condition causing bladder pain and sometimes pelvic pain. The exact cause of interstitial cystitis is not known. Often, signs and symptoms are hard to elucidate and no single treatment works for everyone. We report two cases of patients affected by interstitial cystitis treated with endovesical instillation of platelets rich fibrin (PRF). PRF is an autologous component that promotes angiogenesis, tissue growth and repair. This report presents the safety and the efficacy of PRF instillations in controlling clinical symptoms and restoring quality of life