8 research outputs found

    A New Refinement-Free Preconditioner for the Symmetric Formulation in Electroencephalography

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    Widely employed for the accurate solution of the electroencephalography forward problem, the symmetric formulation gives rise to a first kind, ill-conditioned operator illsuited for complex modelling scenarios. This work presents a novel preconditioning strategy based on an accurate spectral analysis of the operators involved which, differently from other Calderón-based approaches, does not necessitate the barycentric refinement of the primal mesh (i.e., no dual matrix is required). The discretization of the new formulation gives rise to a well-conditioned, symmetric, positive-definite system matrix, which can be efficiently solved via fast iterative techniques. Numerical results for both canonical and realistic head models validate the effectiveness of the proposed formulation

    Inhibiting PCSK9 — biology beyond LDL control

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    A Review of PCSK9 Inhibitors and their Effects on Cardiovascular Diseases

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    Current Treatment of Dyslipidemia: Evolving Roles of Non-Statin and Newer Drugs

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