The MacSharry Challenge: A Farm Simulation Study

A mathematical programming model is used to investigate the effects of the MacSharry Common Agricultural Policy (CAP) reform on crop yields, rotations, and tillage systems of a representative Italian farm. Both professional and small producer regimes are evaluated. The results of the simulation show the profound impact of the policy changes on farm income and land value. No-tillage is introduced to compensate for lower returns, with a strong reductive effect on crop yields. Overall, farm returns are maximized under the professional support regime

An approach to model interest for planetary rover through Dezert-Smarandache Theory

In this paper we propose an approach for assigning an interest level to the goals of a planetary rover. Assigning an interest level to goals, allows the rover to autonomously transform and reallocate the goals. The interest level is defined by data-fusing payload and navigation information. The fusion yields an "interest map", that quantifies the level of interest of each area around the rover. In this way, the planner can choose the most interesting scientific objectives to be analyzed, with limited human intervention, and reallocates its goals autonomously. The Dezert-Smarandache Theory of Plausible and Paradoxical Reasoning was used for information fusion: this theory allows dealing with vague and conflicting data. In particular, it allows us to directly model the behaviour of the scientists that have to evaluate the relevance of a particular set of goals. The paper shows an application of the proposed approach to the generation of a reliable interest map

Near-infrared spectroscopy study of tourniquet-induced forearm ischaemia in patients with coronary artery disease

Near-Infrared Spectroscopy (NIRS) can be employed to monitor local changes in haemodynamics and oxygenation of human tissues. A preliminary study has been performed in order to evaluate the NIRS transmittance response to induced forearm ischaemia in patients with coronary artery disease (CAD). The population consists in 40 patients with cardiovascular risk factors and angiographically documented CAD, compared to a group of 13 normal subjects. By inflating and subsequently deflating a cuff placed around the patient arm, an ischaemia has been induced and released, and the patients have been observed until recovery of the basal conditions. A custom NIRS spectrometer (IRIS) has been used to collect the backscattered light intensities from the patient forearm throughout the ischaemic and the recovery phase. The time dependence of the near-infrared transmittance on the control group is consistent with the available literature. On the contrary, the magnitude and dynamics of the NIRS signal on the CAD patients show deviations from the documented normal behavior, which can be tentatively attributed to abnormal vessel stiffness. These preliminary results, while validating the performance of the IRIS spectrometer, are strongly conducive towards the applicability of the NIRS technique to ischaemia analysis and to endothelial dysfunction characterization in CAD patients with cardiovascular risk factors

An approach to model interest for planetary rover through Dezert–Smarandache theory

In this paper, we propose an approach for assigning an interest level to the goals of a planetary rover. Assigning an interest level to goals allows the rover autonomously to transform and reallocate the goals. The interest level is defined by data-fusing payload and navigation information. The fusion yields an "interest map" that quantifies the level of interest of each area around the rover. In this way the planner can choose the most interesting scientific objectives to be analyzed, with limited human intervention, and reallocates its goals autonomously. The Dezert-Smarandache Theory of Plausible and Paradoxical Reasoning was used for information fusion: this theory allows dealing with vague and conflicting data. In particular, it allows us directly to model the behavior of the scientists that have to evaluate the relevance of a particular set of goals. The paper shows an application of the proposed approach to the generation of a reliable interest map

Genetic Algorithm for Combinatorial Path Planning: The Subtour Problem

The purpose of this paper is to present a combinatorial planner for autonomous systems. The approach is demonstrated on the so-called subtour problem, a variant of the classical traveling salesman problem (TSP): given a set of possible goals/targets, the optimal strategy is sought that connects ≤ goals. The proposed solution method is a Genetic Algorithm coupled with a heuristic local search. To validate the approach, the method has been benchmarked against TSPs and subtour problems with known optimal solutions. Numerical experiments demonstrate the success of the approach

Unrelated bone marrow transplantation in Thalassemia. The experience of the Italian Bone Marrow transplant Group (GITMO)

BACKGROUND AND OBJECTIVES: Allogeneic bone marrow transplantation (BMT) is a widely accepted therapeutic approach in homozygous beta-thalassemia. However, the majority of patients do not have a genotypically identical donor within the family. This prompted us to conduct a pilot study to investigate the feasibility of matched unrelated bone marrow transplantation in thalassemia. The major drawback was the high risk of immunologic and transplant-related complications, mainly graft-versus-host disease (GvHD) and graft failure. DESIGN AND METHODS: Our aim was to reduce this risk through careful selection of donor/recipient pairs. HLA haplotypes that show a high linkage disequilibrium among their class I, class II and class III alleles are considered extended or ancestral haplotypes. RESULTS: These haplotypes are conserved and can be shared by apparently unrelated individuals. Our study shows that matching for these haplotypes significantly improves the outcome of unrelated bone marrow transplantation in thalassemia. In fact, results were comparable to those obtained in transplants using HLA-identifical family donors. INTERPRETATION AND CONCLUSIONS: Better results were obtained in patients with lesser iron overload and when the donor shared an identity for the DPB1 alleles