79 research outputs found
Analysis of Adaptive Traffic Control Systems Design of a Decision Support System for Better Choices
open3siNear half of the world population lives in cities. For many years big cities have faced the dif culties caused by junctions. Junctions and congestion are the cause of many other problems, like air pollution, time waste, delays, increased average trip time, decreased average cruise speed, increased fuel consumption and many others. These important issues cost a lot to governments in terms of both time and money. Cities suffer from the well-known problem of xed-time planning for traf c signals at intersections. In this paper the authors went through these problems and discussed about the dif culties of xed-time plan traf c lights and their solutions. Adaptive traf c control systems are one of the soltions which are exactly opposite to xed-time plans. Four different adaptive traf c control systems will be discussed. Each of them has unique characteristics that make it worthy to compare. The general architecture of these systems is based on a similar concept, but there is a great number of general and detailed differences that makes them interesting to compare. By making a deep comparison between these systems, which is one of the outputs of this research, governments and the authorities in charge can have an appropriate reference to look for their bene ts and choose an adaptive traf c control system to apply to their networks.Studer, Luca; Ketabdari, Misagh; Marchionni, GiovannaStuder, LUCA PASINO; Ketabdari, Misagh; Marchionni, Giovann
La Gestione dei trasporti in emergenza: attività, prodotti e risultati dell'esercitazione nazionale di Protezione Civile in Valtellina
L'articolo riporta l’esperienza maturata dal Laboratorio Mobilità e Trasporti del Politecnico di Milano in qualità di Centro di Competenza per la Gestione e la Sicurezza dei Trasporti per il Dipartimento di Protezione Civile Nazionale durante l’esercitazione nazionale di Protezione Civile in Valtellina.
Le attività svolte, i prodotti realizzati e utilizzati ma soprattutto i risultati e l’esperienza emersi da una esercitazione temporalmente estesa e di estremo rilievo in ambito di Protezione Civile, si ritiene siano ancora estremamente attuali e utili come esempio per la gestione dei trasporti in caso di emergenze rilevanti
Road Users Exposed to Harm from Transportation of Dangerous Goods - Definition and Estimation
The Italian Interreg Project DESTINATION was intended to acquire data on the transportation of dangerous
goods and use them, developing a tool to protect the territory. The Project developed a risk analysis model for
examination and assessment of the elements exposed to harm in the event of accident scenarios involving
hazardous substances. Defining the risk model, the need emerged for a procedure able of explicitly estimating
the number of road users that could be affected in case of dangerous goods accident. After a brief
presentation of the risk model, this paper describes the method adopted for the quantification of the possible
involved road users, in coherence with the Project’s objectives and requirements. Due to the specific nature of
the subject, it was necessary to consider parameters not included in traditional vehicle queuing models, such
as the possibility of assessing users in transit on roads not directly affected by the accident and of
differentiating analyses depending on the temporal development of the event (instantaneous vs. noninstantaneous
events)
Possible Impacts of C-ITS on Supply-Chain Logistics System
The purpose of this research is to introduce an analysis, which is qualitative and whenever possible quantitative, on how Cooperative Intelligent Transport Systems (C-ITS) can affect a Supply-Chain Logistics System by adopting a three-level approach. Considerations are made on the role and importance of Logistics within a company, its cost structure and the strategic relevance it assumes within the Supply-Chain, while considering its evolution from a Physical Distribution Management to a Supply-Chain Management. The increasing importance of logistics requires more sophisticated solutions to reduce or optimize its costs, as well as to find new opportunities to redesign the network configuration and the value-chain. These applications require a careful evaluation method in order to assess their effective adoption. The research is based on a literature review of the most relevant European Road ITS and C-ITS projects evaluation methods and benefits. The result of the investigation is an analysis that classifies the impact of C-ITS on the structure of the Supply-Chain according to different levels. Firstly, the paper reports the different impacts of a large-scale C-ITS deployment on the Logistics cost structure of a company and more in general, on the expected costs. After that, a second level of analysis deals with a possible redesign of the Distribution Network, oriented to the optimization of transportation costs over long distances. Finally, the third step of the analysis investigates a possible impact of C-ITS on the value-chain from several perspectives within the different roles of the subjects involved in the Supply Chain
Notch3 is activated by chronic hypoxia and contributes to the progression of human prostate cancer
Low in‑hospital mortality rate in patients with COVID‑19 receiving thromboprophylaxis: data from the multicentre observational START‑COVID Register
Abstract
COVID-19 infection causes respiratory pathology with severe interstitial pneumonia and extra-pulmonary complications; in particular, it may predispose to thromboembolic disease. The current guidelines recommend the use of thromboprophylaxis in patients with COVID-19, however, the optimal heparin dosage treatment is not well-established. We conducted a multicentre,
Italian, retrospective, observational study on COVID-19 patients admitted to ordinary wards, to describe clinical characteristic of patients at admission, bleeding and thrombotic events occurring during hospital stay. The strategies used for thromboprophylaxis and its role on patient outcome were, also, described. 1091 patients hospitalized were included in
the START-COVID-19 Register. During hospital stay, 769 (70.7%) patients were treated with antithrombotic drugs: low molecular weight heparin (the great majority enoxaparin), fondaparinux, or unfractioned heparin. These patients were more frequently affected by comorbidities, such as hypertension, atrial fibrillation, previous thromboembolism, neurological disease,and cancer with respect to patients who did not receive thromboprophylaxis. During hospital stay, 1.2% patients had a major bleeding event. All patients were treated with antithrombotic drugs; 5.4%, had venous thromboembolism [30.5% deep vein thrombosis (DVT), 66.1% pulmonary embolism (PE), and 3.4% patients had DVT + PE]. In our cohort the mortality rate
was 18.3%. Heparin use was independently associated with survival in patients aged ≥ 59 years at multivariable analysis. We confirmed the high mortality rate of COVID-19 in hospitalized patients in ordinary wards. Treatment with antithrombotic drugs is significantly associated with a reduction of mortality rates especially in patients older than 59 years
Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia
Carbonic anhydrase IX is a marker of hypoxia and correlates with higher Gleason scores and ISUP grading in prostate cancer
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