5,129 research outputs found
Einstein: His Space and Times
The commonly held view of Albert Einstein is of an eccentric genius for whom the pursuit of science was everything. But in actuality, the brilliant innovator whose Theory of Relativity forever reshaped our understanding of time was a man of his times, always politically engaged and driven by strong moral principles. An avowed pacifist, Einstein’s mistrust of authority and outspoken social and scientific views earned him death threats from Nazi sympathizers in the years preceding World War II. To him, science provided not only a means for understanding the behavior of the universe, but a foundation for considering the deeper questions of life and a way for the worldwide Jewish community to gain confidence and pride in itself. This biography presents Einstein in the context of the world he lived in, offering a fascinating portrait of a remarkable individual who remained actively engaged in international affairs throughout his life. This revealing work not only explains Einstein’s theories in understandable terms, it demonstrates how they directly emerged from the realities of his times and helped create the world we live in today. [From the Publisher]https://cupola.gettysburg.edu/books/1089/thumbnail.jp
April Fools’ Day, A Celebration of All Things Creative
April Fools\u27 Day is unique among our holidays because it is the only one for which ingenuity is required. Other festivals are celebrated with expectations of prepackaged icons. Try serving something other than turkey for Thanksgiving and you are likely to face a revolt. Holidays are bastions of repetition, but April Fools\u27 Day is a commemoration of creativity. [excerpt
06. Richard Richards, Robert Roberts, and Aristotelian Aristotelianism
This paper is a tribute to a philosopher and a person I have long admired, Richard C. Richards. As a clear and rigorous thinker, a thoughtful and accessible writer, and as a kind, blunt, and extremely funny person, Richard embodies virtues I hope to someday claim as well. [excerpt
Evolution and the Second Law of Thermodynamics: Effectively Communicating to Non-Technicians
Given the degree of disbelief in the theory of evolution by the wider public, scientists need to develop a collection of clear explanations and metaphors that demonstrate the working of the theory and the flaws in antievolutionist arguments. This paper presents tools of this sort for countering the anti-evolutionist claim that evolutionary mechanisms are inconsistent with the second law of thermodynamics. Images are provided to replace the traditional misunderstanding of the law, i.e., “everything always gets more disordered over time,” with a more clear sense of the way in which entropy tends to increase allowing a thermally isolated system access to a greater number of microstates. Accessible explanations are also provided for the ways in which individual organisms are able to minimize entropy and the advantages this conveys
00. Introduction
One of the most wonderful aspects of the job of university professor is that one’s occupation is based on an area of personal expertise that shapes one’s Being. So it is with Richard C. “Dick” Richards, who, amongst other areas of specialization, is a philosopher of love. Richard’s Being is one deeply entrenched in love. There is, of course, the romantic love he long shared with his recently passed wife Marty, but there is also the love of many, many students and colleagues, both in and beyond the department at California State Polytechnic University at Pomona, and undeniably his love for poetry, humor, and the philosophy to which he dedicated so many years. Most of all, though, is (as cliché as this sounds), his love of life. Few people so embody the virtues they discuss, living so vitally and thereby affecting the lives of so many who come in contact with them, even briefly, that this love is shared by so many. This volume is intended as a testament to that love given and now redirected back toward Richard C. Richards. [excerpt
Entry & Exit: The Lifecyle of a Hedge Fund
Using data from the TASS/Tremont hedge fund database, this article performs an empirical analysis of the evolution of the hedge fund industry within an industrial organization framework.Hedge Funds, Entry, Exit, Evolution, Hedge Fund Performance, Hedge Fund Styles, Incumbents, Entrants, Lifecyle, Competition, Market for Ideas,
Invariance: A Tale of Intellectual Migration
The plotline of the standard story told about the development of intellectual history at the end of the 19th/turn of the 20th century follows the move from absolutism to perspectivalism. The narrative takes us, on the one hand, from the scientism of late Enlightenment writers like Voltaire, Mill, D’Alebert, and Comte and the historical determinism of Hegel, all of which were based upon a universal picture of rationality, to, on the other hand, the relativistic physics of Einstein, the perspectival art of Picasso, and the individualism of Nietzsche and Kierkegaard leading to the phenomenology of Husserl and Heidegger to and on through the deconstructivist work of Derrida in which universal proclamations were deemed meaningless. In their place, was relative dependent upon subjective, political, and social factors, influences, and interpretations. Like all sketches, of course, the story is more complicated than that.
There is another trend in the intellectual air of the early 20th century that gets left out of this oversimplified picture, one that threads a middle path between absolutism and perspectivalism, a path that considers both frame-dependent or covariant truths and frame-independent or invariant truths and examines the relations between them. Indeed, the notions of covariance and invariance play important roles in the development of the fields of mathematics, physics, philosophy, and psychology in the decades after the turn of the 20th century.
The migration of the concepts of invariance and covariance illustrates not only the interconnectedness of the working communities of intellectuals, but also displays ways in which the personal, social, and political overlaps between groups of disciplinary thinkers are essential conduits for the conceptual cross-fertilization that aids in the health of our modern fields of study. [excerpt
Sylvester: Ushering in the Modern Era of Research on Odd Perfect Numbers
In 1888, James Joseph Sylvester (1814-1897) published a series of papers that he hoped would pave the way for a general proof of the nonexistence of an odd perfect number (OPN). Seemingly unaware that more than fifty years earlier Benjamin Peirce had proved that an odd perfect number must have at least four distinct prime divisors, Sylvester began his fundamental assault on the problem by establishing the same result. Later that same year, he strengthened his conclusion to five. These findings would help to mark the beginning of the modern era of research on odd perfect numbers. Sylvester\u27s bound stood as the best demonstrated until Gradstein improved it by one in 1925. Today, we know that the number of distinct prime divisors that an odd perfect number can have is at least eight. This was demonstrated by Chein in 1979 in his doctoral thesis. However, he published nothing of it. A complete proof consisting of almost 200 manuscript pages was given independently by Hagis. An outline of it appeared in 1980.
What motivated Sylvester\u27s sudden interest in odd perfect numbers? Moreover, we also ask what prompted this mathematician who was primarily noted for his work in algebra to periodically direct his attention to famous unsolved problems in number theory? The objective of this paper is to formulate a response to these questions, as well as to substantiate the assertion that much of the modern work done on the subject of odd perfect numbers has as it roots, the series of papers produced by Sylvester in 1888
HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in bunionectomy: phase III results from the randomized EPOCH 1 study.
BACKGROUND AND OBJECTIVES: There is a need for local anesthetics that provide consistent analgesia through 72 hours after surgery. This study evaluates the use of HTX-011 (bupivacaine and meloxicam in Biochronomerpolymer technology), an extended-release, dual-acting local anesthetic, in reducing both postoperative pain over 72 hours and postoperative opioid use when compared with bupivacaine hydrochloride (HCl) and saline placebo. Inclusion of low-dose meloxicam in HTX-011 is designed to reduce local inflammation caused by surgery, potentiating the analgesic effect of bupivacaine. Previously, significant synergy has been observed with bupivacaine and meloxicam with both given locally together.
METHODS: EPOCH 1 was a randomized, double-blind, placebo-controlled and active-controlled phase III study in subjects undergoing a primary unilateral, distal, first metatarsal bunionectomy in which subjects received either a single intraoperative dose of HTX-011, immediate-release bupivacaine HCl or saline placebo.
RESULTS: A total of 412 subjects were dosed. The results for the primary and all four key secondary endpoints were statistically significant in favor of HTX-011. HTX-011 demonstrated superior, sustained pain reduction through 72 hours, significantly reduced opioid consumption and resulted in significantly more opioid-free subjects compared with saline placebo and bupivacaine HCl. Safety was similar across groups with fewer opioid-related adverse events observed in the HTX-011 group.
CONCLUSIONS: HTX-011 demonstrated significant reduction in postoperative pain through 72 hours with significant reduction in opioid consumption and a significant increase in the proportion of opioid-free subjects compared with saline placebo and the most widely used local anesthetic, bupivacaine HCl.
TRIAL REGISTRATION NUMBER: NCT03295721
Talking about Writing across the Secondary and College Community
Many have commented that higher education is becoming increasingly fragmented, leading to the overspecialization of scholars, disciplinary discourses that are opaque to those outside the field, and lack of cross-pollination among disciplines (Kerr). WAC has long been seen as a movement that creates connections among disciplines. In fact, these connections are often created through the workshop, the quintessential WAC experience, as it “bring[s] faculty together around the same table”—bringing together people who may work at the same institution but, in practice, work worlds apart (Cox 317). More recently, this movement to bring people around the same table has come to include colleagues from secondary education (Childers and Lowry).
While this practice of WAC has long been recognized, it has not been adequately theorized. Writing Across Communities (WACommunities), introduced by Michelle Hall Kells and Juan C. Guerra, was developed to rethink student writing. This approach to WAC asks us to think of student writing holistically, as including students’ literacy and language experiences outside of the classroom—online writing, civic writing, disciplinary writing, writing in languages other than English—as well as the writing students did before they entered our classrooms and what they’ll write after leaving them. In this chapter, we argue that WACommunities is also a productive theory for reconceptualizing relationships among educators, drawing on an event we organized at Bridgewater State University (BSU) as an example of this theory in practice
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