997 research outputs found
Mandatory Arbitration of Employee Discrimination Claims: Unmitigated Evil or Blessing in Disguise?
One of the hottest current issues in employment law is the use of mandatory arbitration to resolve workplace disputes. Typically, an employer will make it a condition of employment that employees must agree to arbitrate any claims arising out of the job, including claims based on statutory rights against discrimination, instead of going to court. On the face of it, this is a brazen affront to public policy. Citizens are being deprived of the forum provided them by law. And indeed numerous scholars and public and private bodies have condemned the use of mandatory arbitration. Yet the insight of that great Nineteenth Century English social philosopher, W.S. Gilbert\u27s Little Buttercup, may apply here: Things are seldom what they seem. Perhaps the validity of mandatory arbitration should depend more on a pragmatic assessment of what is likely to be best in practice for the great majority of workers, employers, and the public, rather than on abstract notions about the inviolability of statutory claims and the sanctity of the right to a jury trial. At least arguably, in light of an overworked, underfunded Equal Employment Opportunity Commission (EEOC) and backlogged federal court dockets, most employees might be better off with mandatory arbitration, even of statutory claims, provided there were due process guarantees and the arbitrator could furnish the full range of statutory remedies
Unusual features of pomoviral RNA movement
This work is partially supported by the Scottish Governmentās Rural and Environment Science and Analytical Services (RESAS) DivisionPotato mop-top pomovirus (PMTV) is one of a few viruses that can move systemically in plants in the absence of the capsid protein (CP). Pomoviruses encode the triple gene block genetic module of movement proteins (TGB 1, 2, and 3) and recent research suggests that PMTV RNA is transported either as ribonucleoprotein (RNP) complexes containing TGB1 or encapsidated in virions containing TGB1. Furthermore, there are different requirements for local or systemic (long-distance) movement. Research suggests that nucleolar passage of TGB1 may be important for the long-distance movement of both RNP and virions. Moreover, and uniquely, the long-distance movement of the CP-encoding RNA requires expression of both major and minor CP subunits and is inhibited when only the major CP sub unit is expressed. This paper reviews pomovirus research and presents a current model for RNA movement.Publisher PDFPeer reviewe
Islanding, growth mode and ordering in Si heteroepitaxy on Ge(001) substrates structured by thermal annealing
Si/Ge heteroepitaxial dots under tensile strain are grown on nanostructured
Ge substrates produced by high-temperature flash heating exploiting the
spontaneous faceting of the Ge(001) surface close to the onset of surface
melting. A very diverse growth mode is obtained depending on the specific
atomic structure and step density of nearby surface domains with different
vicinal crystallographic orientations. On highly-miscut areas of the Ge(001)
substrate, the critical thickness for islanding is lowered to about 5 ML, in
contrast to the 11 ML reported for the flat Ge(001) surface, while on
unreconstructed (1x1) domains the growth is Volmer-Weber driven. An explanation
is proposed considering the diverse relative contributions of step and surface
energies on misoriented substrates. In addition, we show that the bottom-up
pattern of the substrate naturally formed by thermal annealing determines a
spatial correlation for the dot sites
DETERMINANTS OF STRATEGIC RISK MANAGEMENT IN EMERGING MARKETS SUPPLY CHAINS: THE CASE OF MEXICO
Risk mitigation in global supply chains has grown in importance in recent years, in tandem with globalization and both the commercial and security threats faced by firms both large and small. This study hypothesizes that a firmās ability to manage risk strategyāand therefore support its competitivenessāis determined by a symbiotic triad of factors: the resources it utilizes; network systems; and performance criteria it employs. The study, comprising 24 in-depth interviews with electronics and IT firms, examines resource utilization through the Resource-Based View (RBV), assesses firmsā proclivity to engage in networks for risk mitigation and competitiveness; and highlights the importance of performance evaluation as a critically important component in supply chain management. Findings reveal that both buyers and suppliers believe that the symbiotic triad can provide them with a competitive advantage in addition to improving operational efficiency, effectiveness and quality. Future research should also extend this pilot investigation to other countries and industries, and utilize a larger sample of firms for quantitative as well as qualitative assessment.Risk management; emerging markets; Supply Chain Management; IT
Multi-modal volumetric concept activation to explain detection and classification of metastatic prostate cancer on PSMA-PET/CT
Explainable artificial intelligence (XAI) is increasingly used to analyze the
behavior of neural networks. Concept activation uses human-interpretable
concepts to explain neural network behavior. This study aimed at assessing the
feasibility of regression concept activation to explain detection and
classification of multi-modal volumetric data.
Proof-of-concept was demonstrated in metastatic prostate cancer patients
imaged with positron emission tomography/computed tomography (PET/CT).
Multi-modal volumetric concept activation was used to provide global and local
explanations.
Sensitivity was 80% at 1.78 false positive per patient. Global explanations
showed that detection focused on CT for anatomical location and on PET for its
confidence in the detection. Local explanations showed promise to aid in
distinguishing true positives from false positives. Hence, this study
demonstrated feasibility to explain detection and classification of multi-modal
volumetric data using regression concept activation.Comment: Accepted as: Kraaijveld, R.C.J., Philippens, M.E.P., Eppinga, W.S.C.,
J\"urgenliemk-Schulz, I.M., Gilhuijs, K.G.A., Kroon, P.S., van der Velden,
B.H.M. "Multi-modal volumetric concept activation to explain detection and
classification of metastatic prostate cancer on PSMA-PET/CT." MICCAI workshop
on Interpretability of Machine Intelligence in Medical Image Computing
(iMIMIC), 202
- ā¦