324 research outputs found
Assessment for learning: a critical review of a contested territory
The aim of this research seminar is to engage in a critical exploration of Assessment for Learning (AfL), situated within the higher education research literature. This is timely because AfL is generating significant interest as a way to improve student learning
A journey in the world of craniofacial development: From 1968 to the future
This article is based on my talk at the meeting â3rd Advances in Craniosynostosis: Basic Science to Clinical Practiceâ, held at University College, London, on 25 August 2023. It describes my contribution, together with that of my research team and external collaborators, to the field of craniofacial development. This began with my PhD research on the effects of excess vitamin A in rat embryos, which led to a study of normal as well as abnormal formation of the cranial neural tube. Many techniques for analysing morphogenetic change became available to me over the years: whole embryo culture, scanning and transmission electron microscopy, cell division analysis, immunohistochemistry and biochemical analysis of the extracellular matrix. The molecular revolution of the 1980s, and key collaborations with international research teams, enabled functional interpretation of some of the earlier morphological observations and required a change of experimental species to the mouse. Interactions between the molecular and experimental analysis of craniofacial morphogenesis in my laboratory with specialists in molecular genetics and clinicians brought my research journey near to my original aim: to contribute to a better understanding of the causes of human congenital anomalies
From Anti-Exceptionalism to Feminist Logic
Anti-exceptionalists about formal logic think that logic is continuous with the sciences. Many philosophers of science think that there is feminist science. Putting these together: can anti-exceptionalism make space for feminist logic? The answer depends on the details of the ways logic is like science and the ways science can be feminist. This paper wades into these details, examines five different approaches, and ultimately argues that anti-exceptionalism makes space for feminist logic in several different ways
Science practical work: what types of knowledge do secondary science teachers use?
Includes bibliographical references.The prominence of practical work in science curricula today infers that these activities offer unique learning experiences for achieving specific goals. Yet, but for a few exceptions, practical work in school science is often neglected and has not been effective in achieving the goals normally associated with it. The rationale behind this study was that an understanding of the bases for decisions made as teachers plan, enact and assess practical work in Grade 8 and 9 natural sciences, may reveal the nature of the knowledge base required for effective practical work. It was thought that such insight might also shed light on some of the reasons for the apparent lack of effective practical work in South African schools. Furthermore it could inform the design of those aspects of pre - service and in - service teacher professional learning programmes aimed at developing the knowledge and skills required for effective practical work. There is a paucity of research on the knowledge base required for science practical work and no instruments designed to measure, capture or describe such a knowledge base, were found. The aim of this study was firstly to develop a valid and reliable instrument to facilitate the analysis of what teacher s say and do with respect to practical work, and secondly to get a feel for using this instrument for the purpose it was intended. Informed by literature, and using Shulmanâs notion of pedagogical content knowledge (PCK) as the theoretical lens, the analytical instrument, called the practical work PCK table (PPCK T able), consisting of different categories and sub - categories of knowledge, was developed. A number of strategies were used to improve the validity and reliability of the instrument. These strategies included: i) using the instrument to analyse interviews and lessons of three natural sciences teachers working in three different educational settings, ii) soliciting the input from experts in the field of PCK, and iii) determining the inter - rater agreement in the interpretation of the categories or sub - categories among four raters by calculating the percentage agreement and the Fleissâ kappa statistic. Addressing the shortcomings revealed by these measures culminated in the final version of the instrument, the practical work knowledge table (PracK Table) and its accompanying codebook. The second aim was addressed by conducting a pilot case study to explore the usefulness of the PracK Table as a heuristic device. A series of eight Grade 9 lessons taught by one teacher were observed. Data sources included lesson observations, teacher and learner interviews, worksheets and samples of learnersâ work. The PracK Table was used to identify and describe the knowledge the teacher drew on when he engaged his learners in practical work. This study has shown the construct, âPCK for practical workâ, to be invalid. It also revealed that a useful, valid and reliable instrument could be developed, if it is informed by authoritative literature, and if its validity and reliability are empirically tested in real contexts. In the case study the strengths and weaknesses in a teacherâs knowledge and practice could readily be identified using PracK Table as the analytical tool. The findings of the case study indicate that a broad knowledge base and access to laboratory resources, although necessary, does not always translate into effective practical work. Furthermore, it suggests that for well - qualified, experienced natural sciences teachers, teaching in fairly well - resourced schools, it is their theories about teaching and learning in general that is the main factor that determines the effectiveness of the practical work they engage in. These findings could have significant implications for the development of teacher professional learning programmes
An exploration of physical activity and wellbeing in university employees.
Aims: The aim was to explore levels of physical activity (PA) and mental wellbeing in university employees, as well as barriers to and incentives for workplace PA. Methods: An electronic survey was distributed to all staff at one UK university. The survey consisted of a PA stages of change questionnaire, an international PA questionnaire (short-form), the Warwick-Edinburgh Mental Well-being Scale (WEMWBS), questions on perceived barriers to and incentives for workplace PA, questions on methods of enhancing employee wellbeing and demographics. A self-selected sample participated in two focus groups to explore key themes arising from the survey. Descriptive statistics were reported for survey data; associations between PA and wellbeing were tested for using Kruskal-Wallis with post hoc Mann-Whitney. Descriptive, thematic analysis was performed on focus group transcripts. Results: A total of 502 surveys were completed (34% response rate); 13 staff participated in focus groups. In all, 42% of the sample reported PA below the recommended guideline amount. Females were less active than males (p < 0.005). The mean WEMWBS was 49.2 (95% confidence interval (CI): 48.3-49.9). Low PA levels were related to lower WEMWBS scores, with statistically significant differences in WEMWBS demonstrated between low and moderate PA (p = 0.05) and low and high PA (p = 0.001). Lack of time and perceived expense of facilities were common barriers to workplace PA. The main focus group finding was the impact of university culture on workplace PA and wellbeing. Conclusion: University staff demonstrate PA levels and a relationship between PA and wellbeing similar to the general population. Carefully designed strategies aimed at enhancing PA and wellbeing in university staff are required. The specific cultural and other barriers to workplace PA that exist in this setting should be considered. These results are being used to inform PA and wellbeing interventions whose effectiveness will be evaluated in future research
Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary gland
Macrophages are important regulators of branching morphogenesis during development and postnatally in the mammary gland. Regulation of macrophage dynamics during these processes can therefore have a profound impact on development. We demonstrate here that the developing mammary gland expresses high levels of inflammatory CC-chemokines, which are essential in vivo regulators of macrophage migration. We further demonstrate that the atypical chemokine receptor ACKR2, which scavenges inflammatory CC-chemokines, is differentially expressed during mammary gland development. We have previously shown that ACKR2 regulates macrophage dynamics during lymphatic vessel development. Here, we extend these observations to reveal a novel role for ACKR2 in regulating the postnatal development of the mammary gland. Specifically, we show that Ackr2â/â mice display precocious mammary gland development. This is associated with increased macrophage recruitment to the developing gland and increased density of the ductal epithelial network. These data demonstrate that ACKR2 is an important regulator of branching morphogenesis in diverse biological contexts and provide the first evidence of a role for chemokines and their receptors in postnatal development processes
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